A physiologically relevant, simple outflow boundary model for truncated vasculature

Niema M. Pahlevan; Faisal Amlani; M. Hossein Gorji; Fazle Hussain; Morteza Gharib

doi:10.1007/s10439-011-0246-0

A physiologically relevant, simple outflow boundary model for truncated vasculature

Niema M. Pahlevan, Faisal Amlani, M. Hossein Gorji, Fazle Hussain, Morteza Gharib

Houston Methodist

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

A realistic outflow boundary condition model for pulsatile flow in a compliant vessel is studied by taking into account physiological effects: compliance, resistance, and wave reflection of the downstream vasculature. The new model extends the computational domain with an elastic tube terminated in a rigid contraction. The contraction ratio, the length, and elasticity of the terminal tube can be adjusted to represent effects of the truncated vasculature. Using the wave intensity analysis method, we apply the model to the test cases of a straight vessel and the aorta and find good agreement with the physiological characteristics of blood flow and pressure. The model is suitable for cardiac transient (non-periodic) events and easily employed using so-called black box software.

Original language	English (US)
Pages (from-to)	1470-1481
Number of pages	12
Journal	Annals of Biomedical Engineering
Volume	39
Issue number	5
DOIs	https://doi.org/10.1007/s10439-011-0246-0
State	Published - May 2011

Keywords

Arterial wave reflection
Blood flow
Computer modeling
Fluid-structure interaction

ASJC Scopus subject areas

Biomedical Engineering

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10.1007/s10439-011-0246-0

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abstract = "A realistic outflow boundary condition model for pulsatile flow in a compliant vessel is studied by taking into account physiological effects: compliance, resistance, and wave reflection of the downstream vasculature. The new model extends the computational domain with an elastic tube terminated in a rigid contraction. The contraction ratio, the length, and elasticity of the terminal tube can be adjusted to represent effects of the truncated vasculature. Using the wave intensity analysis method, we apply the model to the test cases of a straight vessel and the aorta and find good agreement with the physiological characteristics of blood flow and pressure. The model is suitable for cardiac transient (non-periodic) events and easily employed using so-called black box software.",

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AU - Hossein Gorji, M.

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AU - Gharib, Morteza

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AB - A realistic outflow boundary condition model for pulsatile flow in a compliant vessel is studied by taking into account physiological effects: compliance, resistance, and wave reflection of the downstream vasculature. The new model extends the computational domain with an elastic tube terminated in a rigid contraction. The contraction ratio, the length, and elasticity of the terminal tube can be adjusted to represent effects of the truncated vasculature. Using the wave intensity analysis method, we apply the model to the test cases of a straight vessel and the aorta and find good agreement with the physiological characteristics of blood flow and pressure. The model is suitable for cardiac transient (non-periodic) events and easily employed using so-called black box software.

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KW - Fluid-structure interaction

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A physiologically relevant, simple outflow boundary model for truncated vasculature

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Keywords

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