TY - JOUR
T1 - A non-invasive approach to monitor anemia during long-duration spaceflight with retinal fundus images and deep learning
AU - Waisberg, Ethan
AU - Ong, Joshua
AU - Zaman, Nasif
AU - Kamran, Sharif Amit
AU - Lee, Andrew G.
AU - Tavakkoli, Alireza
N1 - Funding Information:
NASA Grant [80NSSC20K183]: A Non-intrusive Ocular Monitoring Framework to Model Ocular Structure and Functional Changes due to Long-term Spaceflight.
Publisher Copyright:
© 2022
PY - 2022/5
Y1 - 2022/5
N2 - During spaceflight, astronauts can experience significantly higher levels of hemolysis. With future space missions exposing astronauts to longer periods of microgravity, such as missions to Mars, there will be a need to for better understanding this phenomenon. We have proposed that retinal fundus photography and deep learning may be utilized to help further understand this microgravity-induced, anemic process for future spaceflight. By utilizing astronaut and terrestrial analog metadata, a foundation can be built to develop an algorithm that allows for non-invasive retinal imaging to quantify hemoglobin levels and detect anemia during spaceflight. This approach would allow for a non-invasive retinal photograph that can be done frequently during spaceflight as opposed to an invasive blood draw and subsequent tests.
AB - During spaceflight, astronauts can experience significantly higher levels of hemolysis. With future space missions exposing astronauts to longer periods of microgravity, such as missions to Mars, there will be a need to for better understanding this phenomenon. We have proposed that retinal fundus photography and deep learning may be utilized to help further understand this microgravity-induced, anemic process for future spaceflight. By utilizing astronaut and terrestrial analog metadata, a foundation can be built to develop an algorithm that allows for non-invasive retinal imaging to quantify hemoglobin levels and detect anemia during spaceflight. This approach would allow for a non-invasive retinal photograph that can be done frequently during spaceflight as opposed to an invasive blood draw and subsequent tests.
KW - Long-duration spaceflight
KW - Machine learning
KW - Non-invasive anemia detection
KW - Retinal fundus photo
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U2 - 10.1016/j.lssr.2022.04.004
DO - 10.1016/j.lssr.2022.04.004
M3 - Article
C2 - 35491031
AN - SCOPUS:85129194619
VL - 33
SP - 69
EP - 71
JO - Life Sciences in Space Research
JF - Life Sciences in Space Research
SN - 2214-5524
ER -