A multi-scale residual network for accelerated radial MR parameter mapping

Zhiyang Fu, Sagar Mandava, Mahesh B. Keerthivasan, Zhitao Li, Kevin Johnson, Diego R. Martin, Maria I. Altbach, Ali Bilgin

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


A deep learning MR parameter mapping framework which combines accelerated radial data acquisition with a multi-scale residual network (MS-ResNet) for image reconstruction is proposed. The proposed supervised learning strategy uses input image patches from multi-contrast images with radial undersampling artifacts and target image patches from artifact-free multi-contrast images. Subspace filtering is used during pre-processing to denoise input patches. For each anatomy and relaxation parameter, an individual network is trained. in vivo T1 mapping results are obtained on brain and abdomen datasets and in vivo T2 mapping results are obtained on brain and knee datasets. Quantitative results for the T2 mapping of the knee show that MS-ResNet trained using either fully sampled or undersampled data outperforms conventional model-based compressed sensing methods. This is significant because obtaining fully sampled training data is not possible in many applications. in vivo brain and abdomen results for T1 mapping and in vivo brain results for T2 mapping demonstrate that MS-ResNet yields contrast-weighted images and parameter maps that are comparable to those achieved by model-based iterative methods while offering two orders of magnitude reduction in reconstruction times. The proposed approach enables recovery of high-quality contrast-weighted images and parameter maps from highly accelerated radial data acquisitions. The rapid image reconstructions enabled by the proposed approach makes it a good candidate for routine clinical use.

Original languageEnglish (US)
Pages (from-to)152-162
Number of pages11
JournalMagnetic Resonance Imaging
StatePublished - Nov 2020


  • Convolutional neural networks
  • Deep learning
  • Image reconstruction
  • Multi-contrast imaging
  • T mapping
  • Artifacts
  • Brain/diagnostic imaging
  • Knee/diagnostic imaging
  • Magnetic Resonance Imaging
  • Algorithms
  • Humans
  • Image Processing, Computer-Assisted/methods

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging
  • Biomedical Engineering


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