A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

F Taraballi; L Russo; C Battocchio; G Polzonetti; F Nicotra; L Cipolla

doi:10.1039/c4ob00160e

A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

F Taraballi, L Russo, C Battocchio, G Polzonetti, F Nicotra, L Cipolla

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A new approach for tethering of bioactive molecules via arginine is proposed and validated on collagen 2D matrices. The method involves the introduction of a methyl ketone on arginine side-chains, followed by reaction with model alkoxyamino derivatives.

Original language	English (US)
Pages (from-to)	4089-92
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	12
Issue number	24
DOIs	https://doi.org/10.1039/c4ob00160e
State	Published - Jun 28 2014

Keywords

Animals
Arginine
Biocompatible Materials
Collagen
Guanidine
Horses
Ketones
Lactose
Pyruvaldehyde
Spectrometry, Fluorescence
Spectroscopy, Fourier Transform Infrared
Surface Properties
Journal Article
Research Support, Non-U.S. Gov't

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10.1039/c4ob00160e

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abstract = "A new approach for tethering of bioactive molecules via arginine is proposed and validated on collagen 2D matrices. The method involves the introduction of a methyl ketone on arginine side-chains, followed by reaction with model alkoxyamino derivatives.",

keywords = "Animals, Arginine, Biocompatible Materials, Collagen, Guanidine, Horses, Ketones, Lactose, Pyruvaldehyde, Spectrometry, Fluorescence, Spectroscopy, Fourier Transform Infrared, Surface Properties, Journal Article, Research Support, Non-U.S. Gov't",

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AU - Taraballi, F

AU - Russo, L

AU - Battocchio, C

AU - Polzonetti, G

AU - Nicotra, F

AU - Cipolla, L

PY - 2014/6/28

Y1 - 2014/6/28

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AB - A new approach for tethering of bioactive molecules via arginine is proposed and validated on collagen 2D matrices. The method involves the introduction of a methyl ketone on arginine side-chains, followed by reaction with model alkoxyamino derivatives.

KW - Animals

KW - Arginine

KW - Biocompatible Materials

KW - Collagen

KW - Guanidine

KW - Horses

KW - Ketones

KW - Lactose

KW - Pyruvaldehyde

KW - Spectrometry, Fluorescence

KW - Spectroscopy, Fourier Transform Infrared

KW - Surface Properties

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

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DO - 10.1039/c4ob00160e

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SN - 1477-0520

VL - 12

SP - 4089

EP - 4092

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 24

ER -

A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

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Keywords

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