A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

F Taraballi, L Russo, C Battocchio, G Polzonetti, F Nicotra, L Cipolla

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

A new approach for tethering of bioactive molecules via arginine is proposed and validated on collagen 2D matrices. The method involves the introduction of a methyl ketone on arginine side-chains, followed by reaction with model alkoxyamino derivatives.

Original languageEnglish (US)
Pages (from-to)4089-92
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume12
Issue number24
DOIs
StatePublished - Jun 28 2014

Keywords

  • Animals
  • Arginine
  • Biocompatible Materials
  • Collagen
  • Guanidine
  • Horses
  • Ketones
  • Lactose
  • Pyruvaldehyde
  • Spectrometry, Fluorescence
  • Spectroscopy, Fourier Transform Infrared
  • Surface Properties
  • Journal Article
  • Research Support, Non-U.S. Gov't

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