A local angle compensation method based on kinematics constraints for non-invasive vascular axial strain computations on human carotid arteries

Elizabeth Mercure, François Destrempes, Marie Hélène Roy Cardinal, Jonathan Porée, Gilles Soulez, Jacques Ohayon, Guy Cloutier

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Non invasive vascular elastography (NIVE) was developed to highlight atherosclerotic plaque constituents. However, NIVE motion estimates are affected by artifacts, such as an underestimation of deformations due to projected movement angles with respect to the ultrasound beam, movements of the operator or of the patient during image acquisition. The main objective of this work was to propose a local angle compensation method within small measurement windows for the axial strain based on kinematics constraints, and to introduce a filtering process on the strain time-varying curve to reduce as much as possible the impact of motion artifacts. With such preprocessing, we successfully quantified the strain behavior of near and far walls in longitudinal images of internal carotid arteries without (n=30) and with (n=21) significant atherosclerotic disease (greater than 50% stenosis). Maximum strain rates of 4.49%s-1 for the healthy group and of 2.29%s-1 for the atherosclerotic group were calculated on the far wall of internal carotid arteries; significant differences were found between these values (p=0.001). The minimum strain rates, also on the far wall of internal carotid arteries, of -3.68%s-1 for the healthy group and of -1.89%s-1 for the atherosclerotic group were significantly different as well (p=8×10-4). The mean systolic, diastolic and cumulated axial strains could also distinguish the two groups after normalization by the pressure gradient between acquired images. To conclude, the proposed techniques allowed to differentiate healthy and atherosclerotic carotid arteries and may help to diagnose vulnerable plaques.

Original languageEnglish (US)
Pages (from-to)123-136
Number of pages14
JournalComputerized Medical Imaging and Graphics
Volume38
Issue number2
DOIs
StatePublished - Mar 2014

Keywords

  • Angle-dependence
  • Atherosclerotic plaques
  • Carotid artery
  • Healthy carotids
  • Strain rate
  • Strain tensor
  • Ultrasound elastography
  • Vulnerable carotid plaques

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design

Fingerprint Dive into the research topics of 'A local angle compensation method based on kinematics constraints for non-invasive vascular axial strain computations on human carotid arteries'. Together they form a unique fingerprint.

Cite this