A left ventricle model to predict post-revascularization ejection fraction based on cine magnetic resonance images

Hai Chao Han, John N. Oshinski, David N. Ku, Roderic I. Pettigrew

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The left ventricular ejection fraction (LVEF) is an important clinical indicator of the cardiac function and long-term outcome for patients with coronary artery disease. A biomechanical model of the left ventricle was developed to quantitatively predict postrevascularization LVEF based on noninvasive magnetic resonance imaging. The myocardium was categorized into normal, hibernating, and infarcted regions from the ventricular short-axis images. Assuming that hibernating tissue would potentially regain contractility after revascularization, the expected maximum post-revascularization LVEF was calculated for four patients with chronic left ventricular dysfunction. The predictions were within three ejection fraction points of the follow-up LVEFs. This model may be useful to estimate the outcome and efficacy of revascularization plans.

Original languageEnglish (US)
Pages (from-to)52-55
Number of pages4
JournalJournal of Biomechanical Engineering
Volume124
Issue number1
DOIs
StatePublished - Mar 4 2002

Keywords

  • Cardiac Function
  • Coronary Artery Disease
  • Hibernating Myocardium
  • Myocardial Ischemia

ASJC Scopus subject areas

  • Biomedical Engineering
  • Physiology (medical)

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