TY - GEN
T1 - A high-throughput multi-scale assay for anti-migration compound screening by bioluminescence imaging
T2 - 2007 IEEE/NIH Life Science Systems and Applications Workshop, LISA
AU - Zhao, Hong
AU - Cui, Kemi
AU - Smollen, Patrick
AU - Wong, Stephen TC
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2007
Y1 - 2007
N2 - Anti-migratory drugs constitute a promising strategy for cancer treatments. In present study, we proposed a multi-scale high-throughput anti-migratory assay by bioluminescent imaging, including in vitro 3D cell assay, in vivo anti-migratory assay on Zebrafish embryo xenograft, and mouse metastatic tumor model. The combined assay by bioluminescent imaging is less labor intensive, faster, sensitive, and easily repeatable, which make it attractive for high throughput screening for anti-migration compounds.
AB - Anti-migratory drugs constitute a promising strategy for cancer treatments. In present study, we proposed a multi-scale high-throughput anti-migratory assay by bioluminescent imaging, including in vitro 3D cell assay, in vivo anti-migratory assay on Zebrafish embryo xenograft, and mouse metastatic tumor model. The combined assay by bioluminescent imaging is less labor intensive, faster, sensitive, and easily repeatable, which make it attractive for high throughput screening for anti-migration compounds.
UR - http://www.scopus.com/inward/record.url?scp=50849088013&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=50849088013&partnerID=8YFLogxK
U2 - 10.1109/LSSA.2007.4400899
DO - 10.1109/LSSA.2007.4400899
M3 - Conference contribution
AN - SCOPUS:50849088013
SN - 9781424418138
T3 - 2007 IEEE/NIH Life Science Systems and Applications Workshop, LISA
SP - 120
EP - 123
BT - 2007 IEEE/NIH Life Science Systems and Applications Workshop, LISA
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 8 November 2007 through 9 November 2007
ER -