A genome-wide search for susceptibility genes linked to alcohol dependence

L. E. Peterson; J. S. Barnholtz; G. P. Page; T. M. King; M. De Andrade; C. I. Amos

doi:10.1002/gepi.1370170750

A genome-wide search for susceptibility genes linked to alcohol dependence

L. E. Peterson, J. S. Barnholtz, G. P. Page, T. M. King, M. De Andrade, C. I. Amos

Research Institute

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We performed two-point linkage analysis during a genome-wide search for susceptibility genes that predispose to alcohol dependence with the Collaborative Study on the Genetics on Alcoholism (COGA) data made available for the Genetic Analysis Workshop 11 (GAW11). For chromosomes I and 4 our findings supported results reported by Reich et al. [1998] based on the same data. We found similarity between our findings in regions on chromosomes 8 and 10 and reported results for schizophrenia linkage studies. Differences between our results with COGA data and those obtained by Reich et al. [1998] are due to our use of a lod score method versus their use of the affected relative pair (sib pair) method.

Original language	English (US)
Pages (from-to)	S295-S300
Journal	Genetic Epidemiology
Volume	17
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1002/gepi.1370170750
State	Published - 1999

Keywords

Alcoholism
Genetic linkage analysis

ASJC Scopus subject areas

Genetics(clinical)
Epidemiology

Access to Document

10.1002/gepi.1370170750

Cite this

@article{37656c9e79884df5b51db3f19fab2f27,

title = "A genome-wide search for susceptibility genes linked to alcohol dependence",

abstract = "We performed two-point linkage analysis during a genome-wide search for susceptibility genes that predispose to alcohol dependence with the Collaborative Study on the Genetics on Alcoholism (COGA) data made available for the Genetic Analysis Workshop 11 (GAW11). For chromosomes I and 4 our findings supported results reported by Reich et al. [1998] based on the same data. We found similarity between our findings in regions on chromosomes 8 and 10 and reported results for schizophrenia linkage studies. Differences between our results with COGA data and those obtained by Reich et al. [1998] are due to our use of a lod score method versus their use of the affected relative pair (sib pair) method.",

keywords = "Alcoholism, Genetic linkage analysis",

author = "Peterson, {L. E.} and Barnholtz, {J. S.} and Page, {G. P.} and King, {T. M.} and {De Andrade}, M. and Amos, {C. I.}",

year = "1999",

doi = "10.1002/gepi.1370170750",

language = "English (US)",

volume = "17",

pages = "S295--S300",

journal = "Genetic Epidemiology",

issn = "0741-0395",

publisher = "Wiley",

number = "SUPPL. 1",

}

TY - JOUR

T1 - A genome-wide search for susceptibility genes linked to alcohol dependence

AU - Peterson, L. E.

AU - Barnholtz, J. S.

AU - Page, G. P.

AU - King, T. M.

AU - De Andrade, M.

AU - Amos, C. I.

PY - 1999

Y1 - 1999

N2 - We performed two-point linkage analysis during a genome-wide search for susceptibility genes that predispose to alcohol dependence with the Collaborative Study on the Genetics on Alcoholism (COGA) data made available for the Genetic Analysis Workshop 11 (GAW11). For chromosomes I and 4 our findings supported results reported by Reich et al. [1998] based on the same data. We found similarity between our findings in regions on chromosomes 8 and 10 and reported results for schizophrenia linkage studies. Differences between our results with COGA data and those obtained by Reich et al. [1998] are due to our use of a lod score method versus their use of the affected relative pair (sib pair) method.

AB - We performed two-point linkage analysis during a genome-wide search for susceptibility genes that predispose to alcohol dependence with the Collaborative Study on the Genetics on Alcoholism (COGA) data made available for the Genetic Analysis Workshop 11 (GAW11). For chromosomes I and 4 our findings supported results reported by Reich et al. [1998] based on the same data. We found similarity between our findings in regions on chromosomes 8 and 10 and reported results for schizophrenia linkage studies. Differences between our results with COGA data and those obtained by Reich et al. [1998] are due to our use of a lod score method versus their use of the affected relative pair (sib pair) method.

KW - Alcoholism

KW - Genetic linkage analysis

UR - http://www.scopus.com/inward/record.url?scp=0032749693&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032749693&partnerID=8YFLogxK

U2 - 10.1002/gepi.1370170750

DO - 10.1002/gepi.1370170750

M3 - Article

C2 - 10597452

AN - SCOPUS:0032749693

SN - 0741-0395

VL - 17

SP - S295-S300

JO - Genetic Epidemiology

JF - Genetic Epidemiology

IS - SUPPL. 1

ER -

A genome-wide search for susceptibility genes linked to alcohol dependence

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this