@article{e3733a1ca35f4ee28b43347e54dea42b,
title = "A genome-wide linkage scan for quantitative trait loci underlying obesity related phenotypes in 434 Caucasian families",
abstract = "To identify quantitative trait loci (QTLs) that contribute to obesity, we performed a large-scale whole genome linkage scan (WGS) involving 4,102 individuals from 434 Caucasian families. The most pronounced linkage evidence was found at the genomic region 20p11-12 for fat mass (LOD = 3.31) and percentage fat mass (PFM) (LOD = 2.92). We also identified several regions showing suggestive linkage signals (threshold LOD = 1.9) for obesity phenotypes, including 5q35, 8q13, 10p12, and 17q11.",
author = "Zhao, {Lan Juan} and Peng Xiao and Liu, {Yong Jun} and Xiong, {Dong Hai} and Hui Shen and Recker, {Robert R.} and Deng, {Hong Wen}",
note = "Funding Information: Acknowledgments Investigators of this work were partially supported by grants from NIH (K01 AR021170-01, R01 AR45349-01, and R01 GM60402-01A1) and an LB595 grant from the State of Nebraska. The genotyping experiment was performed by Marsh-Weld Center for Medical Genetics and supported by NHLBI Mammalian Genotyping Service (Contract Number HV48141).",
year = "2007",
month = mar,
doi = "10.1007/s00439-006-0286-y",
language = "English (US)",
volume = "121",
pages = "145--148",
journal = "Human genetics",
issn = "0340-6717",
publisher = "Springer Verlag",
number = "1",
}