A double-blind randomized trial of cimetidine in acute upper gastrointestinal bleeding

G. G. Birnie, E. M.M. Quigley, G. Allan, B. M. Goudie, F. Kennedy, K. E. McColl, C. MacKay, G. D. Murray, W. Murray, R. Pickard

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Two hundred and thirteen patients were studied in a double-blind trial of cimetidine versus placebo in the treatment of acute upper gastrointestinal haemorrhage. One hundred and six patients were randomly allocated to receive cimetidine and 107 to receive placebo. There was no significant reduction in transfusion requirements, incidence of further haemorrhage, length of stay in hospital, or mortality in the treated group. There was no subgroup of patients with acute upper gastrointestinal bleeding which appeared to benefit from treatment with cimetidine.

Original languageEnglish (US)
Pages (from-to)885-888
Number of pages4
JournalScandinavian Journal of Gastroenterology
Volume19
Issue number7
DOIs
StatePublished - 1984

ASJC Scopus subject areas

  • Gastroenterology

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