A case of monophasic synovial sarcoma presenting as a vulvar mass

Dipika S. Ambani, Beverly White, Alan L. Kaplan, Alberto Ayala

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Background. Synovial sarcoma is the fourth most commonly occurring sarcoma, accounting for 8-10% of all sarcomas. They arise from unknown pleuripotent stem cells that are capable of differentiating into mesenchymal and/or epithelial structures. Synovial sarcoma is characterized by specific chromosomal translocation t (X; 18)(p11, q11). Case. We report the first case of monophasic synovial sarcoma arising in soft tissues of the vulva in a 33-year-old female. Complete excision of the mass was possible with tumor-free margins. Conclusion. Only four previous cases of biphasic synovial sarcoma arising in the vulva have been reported. The finding of the SYT-SSX2 translocation is generally associated with a better prognosis, besides tumor negative margins after excision offer the possibility of a better outlook for this patient.

Original languageEnglish (US)
Pages (from-to)433-436
Number of pages4
JournalGynecologic oncology
Volume100
Issue number2
DOIs
StatePublished - Feb 1 2006

Keywords

  • Monophasic
  • Synovial sarcoma
  • Translocation t (X, 18)(p11, q11)

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

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