6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors

Lei Wang, Adrianne Wallace, Sudhir Raghavan, Siobhan M. Deis, Mike R. Wilson, Si Yang, Lisa Polin, Kathryn White, Juiwanna Kushner, Steven Orr, Christina George, Carrie O'Connor, Zhanjun Hou, Shermaine Mitchell-Ryan, Charles E. Dann, Larry H. Matherly, Aleem Gangjee

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Medicine & Life Sciences

Chemistry