2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolymethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells

Pharmacology, Toxicology and Pharmaceutical Science

• 2,3,7,8-Tetrachlorodibenzodioxin 100%
• Cytochrome P450 1A1 100%
• Cytochrome P450 Family 19 100%
• CYP1B1 100%
• Adrenal Cortex Carcinoma 100%
• Messenger RNA 80%
• Aromatase 80%
• Ethoxyresorufin 40%
• Cytochrome P450 20%
• Androstenedione 20%
• Estrogen Receptor 20%
• Aromatic Hydrocarbon Receptor 20%
• Carcinogen 20%
• Breast Tumor 20%
• Dimethyl Sulfoxide 20%
• Aromatic Hydrocarbon 20%
• EC50 20%
• Estrone 20%
• Cruciferous Vegetables 20%
• 3 Indolemethanol 20%

Keyphrases

• Cytochrome P450 1A1 (CYP1A1) 100%
• 2,3,7,8-tetrachlorodibenzo-p-dioxin 100%
• Adrenocortical Carcinoma Cells 100%
• Diindolylmethane 100%
• H295R 100%
• MRNA Level 30%
• Aromatase 20%
• Ethoxyresorufin-O-deethylase 20%
• CYP19 20%
• Aromatase Activity 20%
• H295R Cells 20%
• Estrogen Receptor 10%
• Fold Increase 10%
• Metabolism 10%
• Estrogen 10%
• High Concentration 10%
• Rodents 10%
• Structural Analogues 10%
• Tumor Growth 10%
• Stomach 10%
• IC50 Value 10%
• Dimethyl Sulfoxide 10%
• Androstenedione 10%
• Aryl Hydrocarbon 10%
• Cytochrome P450 Enzymes 10%
• Mammary Tumor 10%
• Carcinogen-induced 10%
• Methane 10%
• Estrogen Synthesis 10%
• Estrone 10%
• Aryl Hydrocarbon Receptor 10%
• CYP1B1 10%
• Cruciferous Vegetables 10%
• Signaling Crosstalk 10%
• Indole-3-carbinol 10%
• Estrogen Metabolism 10%
• CYP1A1/1B1 10%
• Central Carbon 10%
• Acid-catalyzed Condensation 10%
• Condensation Products 10%