2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept

Nandita Nadig; Adarsh Bhimraj; Kelly Cawcutt; Kathleen Chiotos; Amy L. Dzierba; Arthur Y. Kim; Greg S. Martin; Jeffrey C. Pearson; Amy Hirsch Shumaker; Lindsey R. Baden; Roger Bedimo; Vincent Chi Chung Cheng; Kara W. Chew; Eric S. Daar; David V. Glidden; Erica J. Hardy; Steven Johnson; Jonathan Z. Li; Christine MacBrayne; Mari M. Nakamura; Laura Riley; Robert W. Shafer; Shmuel Shoham; Pablo Tebas; Phyllis C. Tien; Jennifer Loveless; Yngve Falck-Ytter; Rebecca L. Morgan; Rajesh T. Gandhi

doi:10.1093/cid/ciaf354

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept

Nandita Nadig, Adarsh Bhimraj, Kelly Cawcutt, Kathleen Chiotos, Amy L. Dzierba, Arthur Y. Kim, Greg S. Martin, Jeffrey C. Pearson, Amy Hirsch Shumaker, Lindsey R. Baden, Roger Bedimo, Vincent Chi Chung Cheng, Kara W. Chew, Eric S. Daar, David V. Glidden, Erica J. Hardy, Steven Johnson, Jonathan Z. Li, Christine MacBrayne, Mari M. NakamuraLaura Riley, Robert W. Shafer, Shmuel Shoham, Pablo Tebas, Phyllis C. Tien, Jennifer Loveless, Yngve Falck-Ytter, Rebecca L. Morgan, Rajesh T. Gandhi

Research output: Contribution to journal › Article › peer-review

Abstract

This article provides a focused update to the clinical practice guideline on the treatment and management of patients with coronavirus disease 2019 (COVID-19), developed by the Infectious Diseases Society of America. The guideline panel presents a recommendation on the use of abatacept in hospitalized adults with severe or critical COVID-19. The recommendation is based on evidence derived from a systematic literature review and adheres to a standardized methodology for rating the certainty of evidence and strength of recommendation according to the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) approach.

Original language	English (US)
Pages (from-to)	i17-i21
Journal	Clinical Infectious Diseases
Volume	81
DOIs	https://doi.org/10.1093/cid/ciaf354
State	Published - Oct 15 2025

Keywords

COVID-19
SARS-CoV-2
abatacept
guideline

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1093/cid/ciaf354

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Nadig, N., Bhimraj, A., Cawcutt, K., Chiotos, K., Dzierba, A. L., Kim, A. Y., Martin, G. S., Pearson, J. C., Shumaker, A. H., Baden, L. R., Bedimo, R., Cheng, V. C. C., Chew, K. W., Daar, E. S., Glidden, D. V., Hardy, E. J., Johnson, S., Li, J. Z., MacBrayne, C., ... Gandhi, R. T. (2025). 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept. Clinical Infectious Diseases, 81, i17-i21. https://doi.org/10.1093/cid/ciaf354

Nadig, N, Bhimraj, A, Cawcutt, K, Chiotos, K, Dzierba, AL, Kim, AY, Martin, GS, Pearson, JC, Shumaker, AH, Baden, LR, Bedimo, R, Cheng, VCC, Chew, KW, Daar, ES, Glidden, DV, Hardy, EJ, Johnson, S, Li, JZ, MacBrayne, C, Nakamura, MM, Riley, L, Shafer, RW, Shoham, S, Tebas, P, Tien, PC, Loveless, J, Falck-Ytter, Y, Morgan, RL & Gandhi, RT 2025, '2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept', Clinical Infectious Diseases, vol. 81, pp. i17-i21. https://doi.org/10.1093/cid/ciaf354

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title = "2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept",

abstract = "This article provides a focused update to the clinical practice guideline on the treatment and management of patients with coronavirus disease 2019 (COVID-19), developed by the Infectious Diseases Society of America. The guideline panel presents a recommendation on the use of abatacept in hospitalized adults with severe or critical COVID-19. The recommendation is based on evidence derived from a systematic literature review and adheres to a standardized methodology for rating the certainty of evidence and strength of recommendation according to the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) approach.",

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author = "Nandita Nadig and Adarsh Bhimraj and Kelly Cawcutt and Kathleen Chiotos and Dzierba, \{Amy L.\} and Kim, \{Arthur Y.\} and Martin, \{Greg S.\} and Pearson, \{Jeffrey C.\} and Shumaker, \{Amy Hirsch\} and Baden, \{Lindsey R.\} and Roger Bedimo and Cheng, \{Vincent Chi Chung\} and Chew, \{Kara W.\} and Daar, \{Eric S.\} and Glidden, \{David V.\} and Hardy, \{Erica J.\} and Steven Johnson and Li, \{Jonathan Z.\} and Christine MacBrayne and Nakamura, \{Mari M.\} and Laura Riley and Shafer, \{Robert W.\} and Shmuel Shoham and Pablo Tebas and Tien, \{Phyllis C.\} and Jennifer Loveless and Yngve Falck-Ytter and Morgan, \{Rebecca L.\} and Gandhi, \{Rajesh T.\}",

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doi = "10.1093/cid/ciaf354",

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AU - Dzierba, Amy L.

AU - Kim, Arthur Y.

AU - Martin, Greg S.

AU - Pearson, Jeffrey C.

AU - Shumaker, Amy Hirsch

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AU - Glidden, David V.

AU - Hardy, Erica J.

AU - Johnson, Steven

AU - Li, Jonathan Z.

AU - MacBrayne, Christine

AU - Nakamura, Mari M.

AU - Riley, Laura

AU - Shafer, Robert W.

AU - Shoham, Shmuel

AU - Tebas, Pablo

AU - Tien, Phyllis C.

AU - Loveless, Jennifer

AU - Falck-Ytter, Yngve

AU - Morgan, Rebecca L.

AU - Gandhi, Rajesh T.

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2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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