1,1-Bis(3′-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth

Keyphrases

• Nurr1 100%
• Bladder Cancer 100%
• Orphan nuclear Receptor 100%
• Cancer Growth 100%
• Methane 100%
• Chlorophenyl 100%
• Indolyl 100%
• Methylene 25%
• Diindolylmethane 25%
• Small Interfering RNA (siRNA) 16%
• Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) 16%
• Poly(ADP-ribose) Polymerase 16%
• Novel Agents 8%
• Nude Mice 8%
• Urinary Bladder 8%
• RNA Interference 8%
• Transcription Factor 8%
• Cell Survival 8%
• Ligand-binding Domain 8%
• DNA Fragmentation 8%
• Bladder Tumor 8%
• Ligand-independent Activation 8%
• Endogenous Ligand 8%
• Orthotopic Model 8%
• Cell Death Pathways 8%
• MTT Assay 8%
• Nerve Growth Factor 8%
• Active Compounds 8%
• Bladder Cancer Therapy 8%
• Bladder Cancer Cells 8%
• Bladder Cancer Cell Lines 8%
• Human Bladder Cancer Cells 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Cancer Growth 100%
• Nuclear Receptor Related Factor 1 100%
• Bladder Cancer 100%
• Orphan Nuclear Receptor 100%
• Carbene 60%
• Tumor Necrosis Factor Related Apoptosis Inducing Ligand 40%
• Small Interfering RNA 40%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 40%
• Nude Mouse 20%
• Transcription Factor 20%
• Bladder Tumor 20%
• Fibrinogen 20%
• Nerve Growth Factor 20%