Abstract
Nanomedicine is one of the most innovatively dynamic areas in today’s biological and medical study, and is showing great promise in the treatment of complex diseases such as cancer. With the rapid development of nanobiotechnology in recent years, robotic nanosystems capable of performing precise and sophisticated operations in vivo have attracted much attention. In this paper, we have summarized our team’s representative work on anti-tumor nanotherapeutics, including the rational design, accurate in-vivo control, and innovative therapeutic application of robotic nanosystems based on biological modules such as nucleic acids, peptides, and membrane structures. For each type of nanosystems, we have discussed their major advantages and anti-tumor therapeutic platforms, and in the context of the most important trends of current clinical oncology, we have also discussed their potential contribution to the innovation of therapeutic paradigms.
| Translated title of the contribution | Rationally designed robotic nanotherapeutics and their anti-tumor applications |
|---|---|
| Original language | Chinese (Traditional) |
| Pages (from-to) | 734-752 |
| Number of pages | 19 |
| Journal | Scientia Sinica Chimica |
| Volume | 54 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2024 |
Keywords
- anti-tumor nanomedicine
- cancer immunotherapy
- controlled self-assembly
- intelligent nanomaterials
- nanorobots
- tumor microenvironment
ASJC Scopus subject areas
- Chemistry(all)
- Biochemistry
- Chemical Engineering(all)
- Materials Chemistry