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  U.S. Study to Protect Brain Health through Lifestyle Intervention to Reduce Risk:Neuroimaging Ancillary Study

  Masdeu, J. C.

  4/1/20 → 6/30/23

  Project: Federal Funding Agencies

• LEAP-012 - MERCK (7902-012, Site No. 0784) Safety and Efficacy of Lenvatinib (E7080 / MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable / Non-metastatic Hepatocellular Carcinoma (MK-7902-012 / E7080-G000-318 / LEAP-012)

  Kodali, S., Abdelrahim, M., Ghobrial, R. M., Gibbs, J. M., Heyne, K., Saharia, A., Shetty, A. & Victor, III, D. W.

  3/27/20 → …

  Project: Clinical Trial

• A Pilot Randomized Controlled Trial of De Novo Belatacept-Based Immunosuppression in Lung Transplantation

  Huang, H. J.

  3/26/20 → 3/25/45

  Project: Non Profit

• AOCT - COVID-19 Plasma Donation

  Castillo, B., Chen, J. & Leveque, C.

  3/26/20 → …

  Project: Clinical Trial

• Phase 2, Open-Label Safety and Efficacy Study of Telisotuzumab Vedotin (ABBV-399) in Subjects With Previously Treated c-Met+ Non-Small Cell Lung Cancer

  Bernicker, E. H., Heyne, K., Singh, M. & Zhang, J.

  3/24/20 → …

  Project: Clinical Trial

• Clinical Validation of the InterVenn Ovarian CAncer Liquid Biopsy (VOCAL)

  Kamat, A. A., Alaniz, A., Suri, A. & Zaid, T.

  3/12/20 → …

  Project: Clinical Trial

• Exercise Intervention for Strong and Fit Pediatric Fontan Patients (StrongFitFontan)

  Cooke, J. P.

  3/10/20 → 2/28/25

  Project: Federal Funding Agencies

• INTEGRATION OF IMMUNOTHERAPY INTO ADJUVANT THERAPY FOR RESECTED NSCLC: ALCHEMIST CHEMO-IO (ACCIO)

  Bernicker, E. H. & Zhang, J.

  3/6/20 → 3/5/45

  Project: Non Profit

• ALLIANCE A221602: OLANZAPINEWITH ORWITHOUT FOSAPREPITANT FOR THE PREVENTION OF CHEMOTHERAPY INDUCED NAUSEA AND VOMITING (CINV) IN PATIENTS RECEIVING HIGHLY EMETOGENIC CHEMOTHERAPY (HEC): A PHASE III RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

  Darcourt, J., Bernicker, E. H., Chang, J. C., Geyer, C. E., Heyne, K. & Niravath, P. A.

  3/6/20 → 3/5/45

  Project: Non Profit

• CTSU - IRB SUBMISSIONA Phase III Trial To Evaluate The Efficacy Of The Addition Of Inotuzumab Ozogamicin (A Conjugated Anti-Cd22 Monoclonal Antibody) To Frontline Therapy In Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL.

  Abdelrahim, M., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  3/6/20 → 3/5/45

  Project: Non Profit

• The COMPASSHER2 Trials (COMprehensive Use of Pathologic Response ASSessment to Optimize Therapy in HER2-Positive Breast Cancer): COMPASSHER2 Residual Disease (RD), A Double-Blinded, Phase III Randomized Trial of T-DM1 and Placebo Compared with T-DM1 and

  3/6/20 → 3/5/45

  Project: Non Profit

• Imaging the mechanical microenvironment in cancers using ultrasound

  Chua, C. Y. X. & Chang, J. C.

  3/1/20 → 2/28/23

  Project: Federal Funding Agencies

• Molecular mechanism of streptococcal adaptation to host nutritional defenses

  Kumaraswami, M. & Olsen, R. J.

  2/25/20 → 1/31/25

  Project: Federal Funding Agencies

• Multicenter Phase II Trial of Durvalumab (MEDI4736) With Trastuzumab and Pertuzumab Combination in HER2-Enriched and HER2-Amplified Breast Cancer (DTP Trial)

  Chang, J. C. & Niravath, P. A.

  2/21/20 → …

  Project: Clinical Trial

• Ocrelizumab for Psychosis by Autoimmunity (OPA)

  Masdeu, J. C., Faridar, A., Nakawah, M. O., Pascual, B., Toledo, J. B. & Weinstein, B.

  2/20/20 → …

  Project: Clinical Trial

• Biophysical roles of pre-metastatic niche evolution on transport of circulating tumor cells

  Kojic, M., Liu, X. & Qin, L.

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Wong, S. T., Zhao, H., Rostomily, R. C. & Sheng, J.

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• Mild Hypothermia and Acute Kidney Injury AKI in Liver Transplantation MHALT Trial

  Ghobrial, R. M., Lindberg, S., Mobley, C. M., Saharia, A. & Victor, III, D. W.

  2/10/20 → …

  Project: Clinical Trial

• Assessing CSF flow in glymphatics

  Britz, G. W., Golanov, E. V., Karmonik, C. & Regnier-Golanov, A.

  2/5/20 → …

  Project: Clinical Trial

• AOCT - Zephyr Valve Registry ZEVR

  Kopas, L.

  2/3/20 → …

  Project: Clinical Trial

• Role of integrin VLA-6 in suppression of bone formation in myeloma

  Yang, J.

  2/1/20 → 1/31/23

  Project: Federal Funding Agencies

• Ultra High-Field MR Spectroscopy of Non-alcoholic fatty liver disease

  Victor, III, D. W., Ghobrial, R. M., Graviss, E. A., Gupta, N. & Karmonik, C.

  1/30/20 → …

  Project: Clinical Trial

• Improving Non-Invasive Diagnosis and Grading of Cartilage Defects in the Knee - Accuracy of Ultra High Field 7-Tesla MRI as Compared With Arthroscopy

  McCulloch, P., Gupta, N. & Harris, J. D.

  1/30/20 → …

  Project: Clinical Trial

• PETCT for Vascular Graft Infection

  Rahimi, M., Al-Mallah, M., Le, L., Lumsden, A. B. & Peden, E. K.

  1/28/20 → …

  Project: Clinical Trial

• REDUCE PAS

  Lin, C. H., Chiu, D., Gadhia, R. R., Kleiman, N., Misra, V. & Volpi, J. J.

  1/28/20 → …

  Project: Clinical Trial

• Regulation of Type I Immunity in diet induced obesity

  Lewis, D. E.

  1/27/20 → 12/31/23

  Project: Federal Funding Agencies

• Chart Review Study Leucovorin 5-FULV

  Abdelrahim, M.

  1/15/20 → …

  Project: Clinical Trial

• TruGraf II - PO#US123417214

  Knight, R. J., Gaber, A. O. & Yi, S.

  1/15/20 → …

  Project: Clinical Trial

• GILENYA

  Gaber, A. O., Ghobrial, R. M., Graviss, E. A., Hobeika, M. J., Kloc, M., Moore, L. W. & Yi, S.

  1/13/20 → …

  Project: Clinical Trial

• Meniscus Repair using precision immunomodulatory tissue engineering

  Taraballi, F. & Incavo, S. J.

  1/1/20 → 12/31/22

  Project: Non Profit

• Neoadjuvant Atezolizumab in Patients With Non-Metastatic Resectable High-Risk Cutaneous Melanoma

  Esnaola, N. F., Allenson, K., Bernicker, E. H., Chen, S. & Mohyuddin, N. G.

  12/19/19 → …

  Project: Clinical Trial

• A Phase II Trial of Ribociclib (LEE011) Plus Letrozole in Women With Recurrent Low-Grade Serous Carcinoma of the Ovary, Fallopian Tube or Peritoneum (GOG-3026)

  Kamat, A. A., Alaniz, A., Singh, M., Suri, A. & Zaid, T.

  12/19/19 → …

  Project: Clinical Trial

• CONTRAIL I - CFZ533A2202 (Site 1006)

  Mobley, C. M., Ghobrial, R. M., Hobeika, M. J. & Saharia, A.

  12/17/19 → …

  Project: Clinical Trial

• Zortress® (everolimus) and Myfortic® (enteric-coated mycophenolate sodium) for the Reduction of Calcineurin Inhibitors and Protection of Kidney Function and Abrogation of Chronic Rejection in Liver Transplantation (CRAD001HUS192C) (PO# 3004203722)

  Ghobrial, R. M., Hobeika, M. J., Ibrahim, H. N., Mobley, C. M., Moore, L. W., Saharia, A. & Victor, III, D. W.

  12/6/19 → …

  Project: Clinical Trial

• Atheroprotection via Reduced Plasma High Density Lipoprotein-Free Cholesterol Bioavailability

  Pownall, H. J., Rosales, C. & Gillard, B. K.

  12/1/19 → 11/30/23

  Project: Federal Funding Agencies

• EP - TRAVERSE

  Valderrábano, M., Dave, A., Fung, S. H., Lador, A., Mathuria, N. & Schurmann, P. A.

  11/25/19 → …

  Project: Clinical Trial

• NRG-GY018. Also PRO00022968

  Zaid, T., Alaniz, A., Singh, M. & Suri, A.

  11/22/19 → …

  Project: Clinical Trial

• Multi-arm Optimization of Stroke Thrombolysis (MOST)

  Misra, V., Chiu, D., Gadhia, R. R., Garg, T. & Volpi, J. J.

  11/19/19 → …

  Project: Clinical Trial

• PLOTS - Registry

  Kim, M. P. & Chan, E. Y.

  11/8/19 → …

  Project: Clinical Trial

• AOCT - Sugar Land - AEGIS-II

  Kleiman, N.

  11/1/19 → …

  Project: Clinical Trial

• Association of LVAD inflow cannula position with the development of acquired VWD and altered angiogenesis

  Kassi, M., Bhimaraj, A., Graviss, E. A., Guha, A., Hussain, I., Kim, J. H. & Youker, K. A.

  10/30/19 → …

  Project: Clinical Trial

• 18F-MK-6240 Tau PET and Brain Inflammation in Alzheimer’s Disease

  Masdeu, J. C., Faridar, A., Fujita, M., Karmonik, C., Nakawah, M. O., Pascual, B. & Roman, G. C.

  10/29/19 → …

  Project: Clinical Trial

• A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of K0706 in Subjects With Early Parkinson's Disease

  Ondo, W. G. & Waln, O.

  10/22/19 → …

  Project: Clinical Trial

• Pharmacokinetic Analysis of Once-Daily Everolimus and Extended-Release Tacrolimus in Renal Transplant Recipients (CRAD001AUS214T) (PO#3004249477)

  Gaber, A. O., Hobeika, M. J., Knight, R. J., Saharia, A. & Yi, S.

  10/17/19 → …

  Project: Clinical Trial

• Trio Health¿s Real-World IPF Disease Registry TH-IPF

  Safdar, Z. & Sahay, S.

  10/14/19 → …

  Project: Clinical Trial

• Establishing Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1: END-DM1

  Greene, E. P., Ashizawa, T., Shroff, S. & Thonhoff, J. R.

  10/8/19 → …

  Project: Clinical Trial

• 3D Breast Implant

  Chang, J. C., Kim, D. & Niravath, P. A.

  10/3/19 → …

  Project: Clinical Trial

• Trio Health¿s Real-World PAH Disease Registry TH-PAH

  Safdar, Z. & Sahay, S.

  10/2/19 → …

  Project: Clinical Trial

• Novel potential drug targets for treatment of triple negative breast cancer

  Chang, J. C.

  10/1/19 → 9/30/23

  Project: Non Profit

• Dystonia Coalition Projects-3

  Ondo, W. G.

  9/30/19 → 8/31/24

  Project: Non Profit