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  A Phase 2 Open-label Study of Brentuximab Vedotin in Front-line Therapy of Hodgkin Lymphoma (HL) an dCD30-expressing Peripheral T-cell Lymphoma (PTCL) in Older Patients or Patients With Significant Comorbidities Ineligible for Standard Chemotherapy

  Pingali, S. R., Darcourt, J., Petkova, J. & Rice, L.

  7/8/20 → …

  Project: Clinical Trial

• AOCT - Regeneron - R10933-10987-COV-2066

  Salazar, E., Castillo, B. & Leveque, C.

  7/8/20 → …

  Project: Clinical Trial

• AOCT - CALAVI-Efficacy and Safety of Acalabrutinib with Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized with COVID-19

  Khoshnevis, M. R., Al-Saadi, M. A., Gotur, D. B., Hsu, S. H., Moran, D., Pingali, S. R. & Sanchez Leon, R.

  7/8/20 → …

  Project: Clinical Trial

• Clazakizumab - COVID-19

  Al-Saadi, M. A., Gaber, A. O., Goodarzi, A., Graviss, E. A., Moore, L. W., Swan, J. T., Yau, S. W., Youssef, J. G. & Zahiruddin, F.

  7/8/20 → …

  Project: Clinical Trial

• A Phase 2, Multicenter, Single-arm Study of Retreatment With Brentuximab Vedotin in Subjects With Relapsed or Refractory Classic Hodgkin Lymphoma (cHL) or CD30-expressing Peripheral T Cell Lymphoma (PTCL)

  Pingali, S. R., Abdelrahim, M., Bernicker, E. H., Chang, J. C., Darcourt, J., Heyne, K., Niravath, P. A., Petkova, J., Randhawa, J., Rice, L. & Singh, M.

  7/8/20 → …

  Project: Clinical Trial

• SH-PORTICO NG

  Kleiman, N., Faza, N., Gadhia, R. R., Goel, S., Little, S. H., Reardon, M. J. & Volpi, J. J.

  7/8/20 → …

  Project: Clinical Trial

• AOCT - Efficacy and Safety of Remdesivir Plus Tocilizumab Compared with Remdesivir Plus Placebo in Hospitalized Patients with Severe COVID-19 Pneumonia (REMDACTA)

  Gotur, D. B., Jaijakul, S. & Perez, K. K.

  7/7/20 → …

  Project: Clinical Trial

• SH-XyloCor XC001

  Al-Mallah, M., Kleiman, N. & Shah, A. R.

  7/2/20 → …

  Project: Clinical Trial

• An Open-label, Randomized, Controlled Phase 3 Study of Enfortumab Vedotin in Combination With Pembrolizumab With or Without Chemotherapy, Versus Chemotherapy Alone in Previously Untreated Locally Advanced or Metastatic Urothelial Cancer

  Darcourt, J., Singh, M. & Zhang, J.

  7/2/20 → …

  Project: Clinical Trial

• A Novel Non-Invasive Approach for Regaining Self-Assisted Standing after Spinal Cord Injury: Combining Transcutaneous Spinal Stimulation and Functional Electrical Stimulation

  Sayenko, D.

  7/1/20 → 6/30/22

  Project: Non Profit

• Targeting novel checkpoint regulator to control viral myocarditis

  Xing, J., Cooke, J. P., Li, X. C. & Zhang, Z.

  7/1/20 → 6/30/23

  Project: Non Profit

• Integrating imaging mass cytometry with spatial transcriptomics and single-cell RNA-seq for understanding of drug resistance in ovarian cancer

  Wong, S. T.

  7/1/20 → 6/30/21

  Project: State

• Synchrony: Holistic Program for Veterans

  Madan, A. & Fowler, C.

  7/1/20 → 6/30/21

  Project: Non Profit

• Remote controlled nanochannel implant for tunable drug delivery

  Grattoni, A.

  7/1/20 → 10/1/21

  Project: Federal Funding Agencies

• Elucidating the role(s) of cytoplasmic capping in the response to oxidative stress in vascular endothelial cells

  Kiss, D. L.

  7/1/20 → 6/30/23

  Project: Non Profit

• Transcriptional Control of Gliogenesis in the CNS

  Cykowski, M. D.

  7/1/20 → 6/30/21

  Project: Federal Funding Agencies

• Phase 3 Multicenter, Double-Blind, randomized, placebo-controlled trail of Infigratinib for the Adjuvant Treatment of Subjects with Invasive Urothelial Carcinoma with Susceptible FGFR3 Genetic Alterations (PROOF 302)

  Satkunasivam, R., Darcourt, J., Singh, M. & Zhang, J.

  6/26/20 → …

  Project: Clinical Trial

• NeuroRX - COVID-19 - RLF-100 ALIARDS

  Youssef, J. G., Al-Saadi, M. A., Grimes, K. A. & Zahiruddin, F.

  6/26/20 → …

  Project: Clinical Trial

• AOCT - I-MAB Phase 1b2 study of TJ003234 in Subjects with Severe COVID 19

  Gotur, D. B., Hsu, S. H., Moran, D., Perez, K. K. & Sanchez Leon, R.

  6/26/20 → …

  Project: Clinical Trial

• SH-PROTECTED TAVR

  Kleiman, N., Goel, S., Reardon, M. J. & Volpi, J. J.

  6/24/20 → …

  Project: Clinical Trial

• Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer (NRG-GY020)

  Farach, A. M., Alaniz, A., Butler, E. B., Darcourt, J., Haque, W. M., Morgan, P. B., Shadle, K. M., Shkedy, C., Singh, M., Suri, A. & Zaid, T.

  6/22/20 → …

  Project: Clinical Trial

• AOCT-FUJIFILMPhase 2 Proof-of-Concept Study of the Use of Favipiravir v. Standard of Care in Hospitalized Subjects with COVID-19

  Ashraf, M., Jaijakul, S. & Perez, K. K.

  6/19/20 → …

  Project: Clinical Trial

• Gingival Bacteria in AD - GAIN Trial

  Masdeu, J. C., Faridar, A. & Nakawah, M. O.

  6/17/20 → …

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo

  Niravath, P. A., Abdelrahim, M., Arentz, C., Chang, J. C., Darcourt, J., Geyer, C. E., Heyne, K. & Singh, M.

  6/16/20 → …

  Project: Clinical Trial

• CMR for COVID Patients

  Shah, D. J., Graviss, E. A., Malahfji, M., Nasir, K. & Yang, E. Y.

  6/16/20 → …

  Project: Clinical Trial

• Systems-wide analysis of oxidative stress-responsive m6A epitranscriptome

  Weng, Y. & Krencik, R. C.

  6/15/20 → 3/31/25

  Project: Federal Funding Agencies

• HOPE Part 2 - Heron

  Swan, J. T., Caplan, R. E., Gaber, A. O. & Moore, L. W.

  6/5/20 → …

  Project: Clinical Trial

• ALLFTD

  Pascual, B., Faridar, A. & Masdeu, J. C.

  6/1/20 → …

  Project: Clinical Trial

• Influence of pre-analytical factors in glioblastoma MGMT promoter methylation biomarker assay

  Rostomily, R. C., Mitra, S. & Powell, S. Z.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Novel Therapeutic Strategies to Co-Target Undifferentiated Prostate Cancer (PCa) Stem Cells and Bulk PCa Cells

  Shen, H.

  6/1/20 → 5/31/21

  Project: Federal Funding Agencies

• Convergent AI for Precise Breast Cancer Risk Assessment

  Wong, S. T., Chang, J. C. & Ensor, Jr., J. E.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• AOCT-ALXN-Efficacy and Safety Study of IV Ravulizumab in Patients with COVID-19 Severe Pneumonia

  Khoshnevis, M. R., Al-Saadi, M. A., Gotur, D. B., Hsu, S. H., Moran, D., Rice, L. & Sanchez Leon, R.

  5/27/20 → …

  Project: Clinical Trial

• A Phase III, Multicenter, Open-Label, Extension Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow® Device plus Standard of Care in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post Single or Double Lung Transplantation (BT-L-CsA-303-FU (BOSTON-3))

  Goodarzi, A., Yau, S. W. & Youssef, J. G.

  5/27/20 → …

  Project: Clinical Trial

• Phase III Trial of Docetaxel vs. Docetaxel and Radium-223 for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

  Darcourt, J., Heyne, K., Singh, M. & Zhang, J.

  5/27/20 → …

  Project: Clinical Trial

• Prospective Sudden Cardiac Death Risk Stratification Using Cardiac MRI and Echocardiography Machine Learning in Mitral Valve Prolapse.

  Shah, D. J.

  5/26/20 → 4/30/25

  Project: Federal Funding Agencies

• SH-AltaValve.

  Chang, S., Faza, N., Goel, S., Kleiman, N., Lawrie, G. M., Little, S. H. & Reardon, M. J.

  5/19/20 → …

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab With Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Chang, J. C., Darcourt, J., Geyer, C. E. & Niravath, P. A.

  5/19/20 → …

  Project: Clinical Trial

• A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

  Singh, M., Abdelrahim, M., Beinart, G. & Heyne, K.

  5/18/20 → …

  Project: Clinical Trial

• AOCT - AERIN AERWAY For Nasal Airway Obstruction

  Takashima, M.

  5/13/20 → …

  Project: Clinical Trial

• Evaluation of immune responses to CD44-targeted nanovectors for designing a novel anti-tuberculosis host-directed therapy

  Godin, B., Jagannath, C. & Leonard, F.

  5/1/20 → 4/30/21

  Project: Federal Funding Agencies

• iNOINOpulse PULSE-EAP-001_compassionate use for COVID 19

  Youssef, J. G., Sahay, S. & Zahiruddin, F.

  4/28/20 → …

  Project: Clinical Trial

• A Phase 2, Multicenter, Open-label, Safety and Efficacy Study of XERMELO® (Telotristat Ethyl) Plus First-line Chemotherapy in Patients With Locally Advanced, Unresectable, Recurrent or Metastatic Biliary Tract Cancer (BTC)

  Abdelrahim, M., Bernicker, E. H., Chang, J. C., Darcourt, J., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  4/27/20 → …

  Project: Clinical Trial

• A PILOT RANDOMIZED CONTROLLED TRIAL OF DE NOVO BELATACEPT-BASED IMMUNOSUPPRESSION IN LUNG TRANSPLANTATION

  Goodarzi, A. & Yau, S. W.

  4/23/20 → …

  Project: Clinical Trial

• Voice Rest Adherence After Phonomicrosurgery

  Yiu, Y.

  4/20/20 → 3/31/23

  Project: Federal Funding Agencies

• Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

  Randhawa, J., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  4/17/20 → …

  Project: Clinical Trial

• DOD - Dehisced-Wound

  Bonville, D. J. & Rupert, P.

  4/16/20 → …

  Project: Clinical Trial

• Defining the altered FUS-PARP-1-DNA Ligase III axis and its implications to nuclear and mitochondrial genome damage response in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

  Hegde, M., Hamilton, D. J., Horner, P. J. & Wang, H.

  4/15/20 → 3/31/25

  Project: Federal Funding Agencies

• A new conditional TDP¿NLS knock-in mouse model generated using CRISPR/Cas9 technology to study the linkage of TDP-43 pathology to motor and cognitive defects in ALS

  Hegde, M. & Wang, H.

  4/15/20 → 2/28/22

  Project: Federal Funding Agencies

• Biodegradability and Biocompatiblity of a Shape Memory Polymer Wrap to Improve Saphenous Vein Graft Patency in Peripheral and Coronary Artery Bypass Grafting Surgeries

  Peden, E. K., Cooke, J. P. & Karmonik, C.

  4/15/20 → 10/31/21

  Project: Federal Funding Agencies

• Sample and Data Collection for Houston Methodist Cancer Center Research

  Chang, J. C., Bernicker, E. H., Darcourt, J., Heyne, K., Niravath, P. A. & Singh, M.

  4/9/20 → …

  Project: Clinical Trial