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• A Novel Multi-Antigen Vaccine (TNBCvax) to Prevent Triple Negative Breast Cancer

  You, M.

  9/16/21 → 3/15/23

  Project: Federal Funding Agencies

• A novel nanochannel system for sustained delivery of Tenofovir Alafenamide Fumarate and Emtricitabine for HIV pre-exposure prophylaxis

  Grattoni, A.

  National Institutes of Health

  6/20/16 → 5/31/22

  Project: Federal Funding Agencies

• A Novel Non-Invasive Approach for Regaining Self-Assisted Standing after Spinal Cord Injury: Combining Transcutaneous Spinal Stimulation and Functional Electrical Stimulation

  Sayenko, D.

  7/1/20 → 6/30/22

  Project: Non Profit

• A Novel Organoid Platform to Modulate Human Neural Networks Integrated with Glioblastoma Stem Cells

  Krencik, R. C. & Rostomily, R. C.

  8/31/20 → 8/30/22

  Project: State

• A Novel Pathway involving ATM PP1 and I-2

  8/16/10 → 10/31/10

  Project: Federal Funding Agencies

• A Novel Pathway Involving ATM PP1 and I-2

  Mitra, S.

  Natl Inst of Environmental Health Sci

  1/28/10 → 3/31/14

  Project: Federal Funding Agencies

• A Novel Role for MAGI1 in regulating non-canonical LATS signaling and atherosclerotic plaque formation

  Le, N.

  1/1/18 → 2/28/23

  Project: Federal Funding Agencies

• A novel role for polycomb group proteins in androgen signaling and prostate cancer.

  Cao, Q.

  Prostate Cancer Foundation

  5/20/13 → 6/30/18

  Project: Non Profit

• A novel T-cell subset able to kill relapsed cancers

  Yi, Q.

  7/1/16 → 6/30/22

  Project: Federal Funding Agencies

• A novel tool in high- dimensional single-cell space to predict neurotoxicity of CAR T cell therapies

  Lu, Y.

  8/1/21 → 7/31/26

  Project: Federal Funding Agencies

• A novel treatment strategy to target the underlying causes of both the wet and dry forms of AMD

  Fang, L.

  7/1/18 → 6/30/21

  Project: Non Profit

• Antigen specificity, suppressive mechanism & regulation of CD4+ regulatory T cell

  Wang, R.

  National Cancer Institute

  2/17/12 → 7/31/13

  Project: Federal Funding Agencies

• An ultra-sensitive nanomagnetic sensor for the early detection of anaplactic large cell lymphoma

  Zu, Y.

  University of Houston

  5/1/15 → 2/28/19

  Project: State

• AOCT - Amulet IDE Study

  Valderrábano, M.

  Project: Clinical Trial

• AOCT-A Phase 2b, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study with Open-Label Extension to Evaluate the Safety and Efficacy of ST266 Eye Drops in the Treatment of Persistent Corneal Epithelial Defects

  Pandit, R. & Queen, J. H.

  4/20/22 → …

  Project: Clinical Trial

• AOCT - Athena Study

  Friedman, J. D., Albright, S. & Ellsworth, IV, W. A.

  Project: Clinical Trial

• AOCT - ATLAS - Knee Study

  McCulloch, P.

  Project: Clinical Trial

• AOCT - Convalescent Plasma - COVID-19

  Castillo, B., Ashraf, M., Chen, J. & Leveque, C.

  Project: Clinical Trial

• AOCT - COVID-19 Plasma Donation

  Castillo, B., Chen, J. & Leveque, C.

  3/26/20 → …

  Project: Clinical Trial

• AOCT - DISRUPT - Exebacase

  Ashraf, M. & Jaijakul, S.

  Project: Clinical Trial

• AOCT - Intuitive da Vinci SP in Colorectal Surgical Procedures

  6/28/21 → …

  Project: Clinical Trial

• AOCT - MOTIVA Implants CLIN-17-008

  Ellsworth, IV, W. A., Gratzon, A. C. & Spiegel, A.

  12/29/21 → …

  Project: Clinical Trial

• AOCT - Phase 23_PF-07321332RITONAVIR_Low-Risk COVID-19_C4671002

  Youssef, J. G., Goodarzi, A., Yau, S. W. & Zahiruddin, F.

  10/21/21 → …

  Project: Clinical Trial

• AOCT - Phase3_MK4482-013_COVID-19

  Moran, D., Gotur, D. B. & Zahiruddin, F.

  9/15/21 → …

  Project: Clinical Trial

• AOCT - Pilot Study to explore toxicity and efficacy of Secukinumab in COVID-19 disease

  Gotur, D. B., Ashraf, M. & Moran, D.

  Project: Clinical Trial

• AOCT - Sugar Land - AEGIS-II

  Kleiman, N.

  11/1/19 → …

  Project: Clinical Trial

• AOCT - Zephyr Valve Registry ZEVR

  Kopas, L.

  2/3/20 → …

  Project: Clinical Trial

• APEX1 is a critical cytosolic molecule to sense self DNAs in autoimmune diseases

  Zhang, Z.

  Baylor Research Institute

  5/1/14 → 4/30/16

  Project: Federal Funding Agencies

• A Phase 0, Investigator Initiated Study, Evaluating the Impact of Omega 3 Free Fatty Acid Supplementation on Aromatase in Obese Subjects (CTMS# 15-2100)

  Niravath, P. A., Chang, J. C. & Darcourt, J.

  12/1/16 → 11/30/18

  Project: Federal Funding Agencies

• A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

  Singh, M., Abdelrahim, M., Beinart, G. & Heyne, K.

  5/18/20 → …

  Project: Clinical Trial

• A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants With Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

  Project: Clinical Trial

• A Phase 2, Multicenter, Single-arm Study of Retreatment With Brentuximab Vedotin in Subjects With Relapsed or Refractory Classic Hodgkin Lymphoma (cHL) or CD30-expressing Peripheral T Cell Lymphoma (PTCL)

  Pingali, S. R., Ganguly, S., Petkova, J., Rice, L. & Shah, S.

  Project: Clinical Trial

• A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of K0706 in Subjects With Early Parkinson's Disease

  Ondo, W. G. & Waln, O.

  10/22/19 → …

  Project: Clinical Trial

• A Phase 2, Two-Part, Multicenter Study of HTX-011 in Spinal Surgery

  Barber, S., Holman, P., Huang, M. & Moore, L. W.

  Project: Clinical Trial

• A Phase 2/3, Randomized, Double Blind, Placebo Controlled, Multicenter Study to Evaluate the Efficacy and Safety of FP-025 in Patients With Severe to Critical COVID 19 With Associated Acute Respiratory Distress Syndrome (ARDS)

  Zainab, A. & Hsu, S. H.

  Project: Clinical Trial

• A Phase 2a, Double-Blind, Randomized, Active Controlled, Parallel Group Study Evaluating the Efficacy, Safety, and Tolerability of Bezafibrate Administered in Combination with Obeticholic Acid in Subjects with Primary Biliary Cholangitis

  Victor, III, D. W., Kodali, S. & Shetty, A.

  Project: Clinical Trial

• A Phase 2 Open-label Study of Brentuximab Vedotin in Front-line Therapy of Hodgkin Lymphoma (HL) an dCD30-expressing Peripheral T-cell Lymphoma (PTCL) in Older Patients or Patients With Significant Comorbidities Ineligible for Standard Chemotherapy

  Pingali, S. R., Ganguly, S., Petkova, J., Rice, L. & Shah, S.

  Project: Clinical Trial

• A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, 27-Week Trial to Evaluate the Efficacy, Safety, and Tolerability of Two Fixed Doses of Tavapadon in Early Parkinson's Disease (TEMPO-1 TRIAL)

  Ondo, W. G. & Waln, O.

  8/6/20 → …

  Project: Clinical Trial

• A Phase 3, Multi-center, Randomized, Double-blind, Parallel-group, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Sodium Oligomannate (GV-971) in Treatment of Mild to Moderate Alzheimer's Disease (GREEN MEMORY: GREen Valley 971 EvaluatioN Memory)

  Masdeu, J. C. & Faridar, A.

  9/13/21 → …

  Project: Clinical Trial

• A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL, ACTIVE-CONTROLLED STUDY OF TRASTUZUMAB DERUXTECAN (T-DXd) VERSUS TRASTUZUMAB EMTANSINE (T-DM1) IN SUBJECTS WITH HIGH-RISK HER2-POSITIVE PRIMARY BREAST CANCER WHO HAVE RESIDUAL INVASIVE DISEASE IN BREAST OR

  7/6/21 → 7/5/31

  Project: Non Profit

• A Phase 3, Randomized, Controlled Study of Prophylactic and On-demand Treatment of cTTP With BAX 930 (rADAMTS13)

  Rice, L.

  1/3/20 → …

  Project: Clinical Trial

• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

  Shroff, S., Appel, S. H., Greene, E. P. & Thonhoff, J. R.

  10/18/19 → …

  Project: Clinical Trial

• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Compare the Efficacy and Safety of Sotatercept Versus Placebo When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH

  Safdar, Z. & Sahay, S.

  7/30/21 → …

  Project: Clinical Trial

• A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-322)

  Shah, S., Ganguly, S., Petkova, J., Pingali, S. R. & Rice, L.

  Project: Clinical Trial

• A Phase I/II Open-Label, Safety And Preliminary Efficacy Study Of MRx0518 In Combination With Pembrolizumab In Patients With Advanced Malignancies Who Have Progressed On PD-1/PD-L1 Inhibitors

  Bernicker, E. H., Heyne, K. & Zhang, J.

  9/25/20 → …

  Project: Clinical Trial

• A Phase II/III Trial of Neoadjuvant FOLFOX w/ Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection w/ Total Mesorectal Excisio

  Bernicker, E. H., Darcourt, J. & Singh, M.

  University of Michigan

  6/11/13 → 6/10/38

  Project: Non Profit

• A Phase II and Biomarker Study of Dual VEGF/PD-L1 Blockade in Neoadjuvant Setting in Resectable Hepatocellular Carcinoma Patients

  Ghobrial, R. M., Abdelrahim, M. & Kodali, S.

  4/1/21 → 3/31/26

  Project: Federal Funding Agencies

• A Phase IIa randomized, double-blind, placebo-controlled study of the effects of L-serine on Mild Cognitive Impairment (MCI)

  Roman, G. C., Masdeu, J. C. & Pascual, B.

  Project: Clinical Trial

• A Phase IIb/III, Randomized, Double-blind, Placebo-controlled Trial of Troriluzole in Adult Subjects With Spinocerebellar Ataxia

  Ashizawa, T., Ondo, W. G. & Waln, O.

  1/25/17 → …

  Project: Clinical Trial

• A Phase II Clinical tRial of neoADjuVant sAsanlimab and stereotaCtiC body radIatioN thErapy as an in situ vaccine for cisplatin-ineligible Muscle Invasive Bladder Cancer (RAD VACCINE MIBC)

  Satkunasivam, R., Chen, S., Esnaola, N. F., Farach, A. M., Teh, B. S. & Zhang, J.

  1/20/22 → …

  Project: Clinical Trial