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• Potentiation of Multi-peptide Lung Cancer Vaccines with Immune Checkpoint Antagonist CA-170

  You, M. & Yi, Q.

  5/24/21 → 11/23/23

  Project: Federal Funding Agencies

• Effects of Thyroid Hormone Metabolite Treatment for Postmenopausal Heart Repair

  Filgueira, C. S., Bhimaraj, A. & Youker, K. A.

  12/1/21 → 11/30/23

  Project: Federal Funding Agencies

• Mechanism of Intratumoral Transport of Particulate Drugs

  Chen, S.

  6/15/18 → 11/30/23

  Project: Federal Funding Agencies

• Atheroprotection via Reduced Plasma High Density Lipoprotein-Free Cholesterol Bioavailability

  Pownall, H. J., Rosales, C. & Gillard, B. K.

  12/1/19 → 11/30/23

  Project: Federal Funding Agencies

• Platelets promote growth of ovarian cancer

  Wong, S. T.

  12/1/18 → 11/30/23

  Project: Federal Funding Agencies

• Regulation of Type I Immunity in diet induced obesity

  Lewis, D. E.

  1/27/20 → 12/31/23

  Project: Federal Funding Agencies

• Genetic mechanism of conserved ancestral haplotype in SCA10

  Ashizawa, T.

  2/1/19 → 12/31/23

  Project: Federal Funding Agencies

• A Spectroscopic Approach to Overcome the Barriers of Early Familial Hypercholesterolemia Diagnosis

  Filgueira, C. S.

  1/1/22 → 12/31/23

  Project: Federal Funding Agencies

• A local immunoactive patch for the treatment of chronic wounds

  Taraballi, F.

  1/15/22 → 1/14/24

  Project: Federal Funding Agencies

• Human Astrocyte-Based Nanovesicles to Target Neuroinflammation in Alzheimer?s Disease

  Krencik, R. C.

  2/15/22 → 1/31/24

  Project: Federal Funding Agencies

• Nanotechnology-based targeting of breast cancer liver metastases

  Godin, B., Chen, S., Niravath, P. A., Rosato, R. R. & Xu, S.

  3/1/21 → 2/29/24

  Project: Federal Funding Agencies

• Photoacoustic Imaging to Guide Catheter Ablation of Cardiac Arrhythmias

  Mathuria, N.

  4/18/22 → 3/31/24

  Project: Federal Funding Agencies

• Reversal of Heart Failure: Role of Vascular Recovery

  Cooke, J. P. & Youker, K. A.

  7/15/20 → 3/31/24

  Project: Federal Funding Agencies

• Targeting ER stress response in B-cell chronic lymphocytic leukemia

  Hu, A., Pingali, S. R. & Tang, C. A.

  4/1/21 → 3/31/24

  Project: Federal Funding Agencies

• Multi-arm Optimization of Stroke Thrombolysis (MOST): a blinded, randomized controlled adaptive, multi-arm, adjunctive-thrombolysis efficacy trial in ischemic stroke.

  6/1/18 → 4/30/24

  Project: Federal Funding Agencies

• Multi-arm Optimization of Stroke Thrombolysis (MOST): a blinded, randomized controlled adaptive, multi-arm, adjunctive-thrombolysis efficacy trial in ischemic stroke.

  Misra, V.

  6/1/18 → 4/30/24

  Project: Federal Funding Agencies

• Novel Therapeutic Strategies to Co-Target AR+ and AR-/lo Prostate Cancer Cells

  6/1/19 → 5/31/24

  Project: Federal Funding Agencies

• The immunosuppressive function of secretory IgM in tumor-bearing mice

  Tang, C. A. & Yin, Z.

  6/1/21 → 5/31/24

  Project: Federal Funding Agencies

• Long non-coding RNA mediated chromatin remodeling in angiogenesis

  Cooke, J. P.

  7/1/19 → 6/30/24

  Project: Federal Funding Agencies

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  Pascual, B., Faridar, A. & Masdeu, J. C.

  9/15/19 → 6/30/24

  Project: Non Profit

• Neuromodulation and the Neuroimmune Axis of Repair

  Horner, P. J. & Weng, Y.

  7/31/21 → 7/30/24

  Project: Non Profit

• Role of tumor microenvironment-derived cholesterol in CD8+ T-cell exhaustion

  Yi, Q.

  8/1/19 → 7/31/24

  Project: Federal Funding Agencies

• The University of Texas M.D. Anderson Cancer Center SPORE in Hepatocellular Carcinoma

  Cristini, V.

  9/1/20 → 8/31/24

  Project: Federal Funding Agencies

• Chemoprevention of lung cancer by targeting lonidamine to mitochondria

  You, M., Wang, Y., Xiong, D. & Zhang, Q.

  9/1/21 → 8/31/24

  Project: Federal Funding Agencies

• Anatomical Modeling to Improve the Precision of Image Guided Liver Ablation

  Ensor, Jr., J. E. & Ensor, Jr., J. E.

  9/1/19 → 8/31/24

  Project: Federal Funding Agencies

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Wong, S. T., Zhao, H., Rostomily, R. C. & Sheng, J.

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• Molecular mechanism of streptococcal adaptation to host nutritional defenses

  Kumaraswami, M. & Olsen, R. J.

  2/25/20 → 1/31/25

  Project: Federal Funding Agencies

• Bioenergetic potentiation in Alzheimer's Disease as a therapeutic strategy

  Blanco, E.

  2/1/22 → 1/31/25

  Project: Non Profit

• Biophysical roles of pre-metastatic niche evolution on transport of circulating tumor cells

  Kojic, M., Liu, X. & Qin, L.

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Wong, S. T., Zhao, H. & Sheng, J.

  8/1/20 → 1/31/25

  Project: Federal Funding Agencies

• A Phase III Randomized, Placebo-Controlled Study of Pembrolizumab (MK-3475, NSC #776864)) in addition to Paclitaxel and Carboplatin for Measurable Stage III or IVA, Stage IVB or Recurrent Endometrial Cancer

  Kamat, A. A., Darcourt, J., Singh, M., Suri, A. & Zaid, T.

  3/1/19 → 2/28/25

  Project: Non Profit

• NRG-BR004: A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Geyer, C. E., Chang, J. C., Darcourt, J. & Niravath, P. A.

  3/12/19 → 2/28/25

  Project: Non Profit

• Exercise Intervention for Strong and Fit Pediatric Fontan Patients (StrongFitFontan)

  Cooke, J. P.

  3/10/20 → 2/28/25

  Project: Federal Funding Agencies

• RE-ENERGIZE FONTAN - RandomizEd Exercise INtERvention desiGned to MaximIZE Fitness in Pediatric FONTAN patients

  Cooke, J. P.

  3/26/21 → 2/28/25

  Project: Federal Funding Agencies

• Novel carbon nanozyme mechanisms for traumatic brain injury therapy

  Hegde, M.

  4/1/20 → 3/31/25

  Project: Federal Funding Agencies

• Systems-wide analysis of oxidative stress-responsive m6A epitranscriptome

  Weng, Y. & Krencik, R. C.

  6/15/20 → 3/31/25

  Project: Federal Funding Agencies

• Age-related TDP-43 neuropathology: using disease-driving mechanisms to guide classification

  Cykowski, M. D.

  9/15/20 → 3/31/25

  Project: Federal Funding Agencies

• Defining the altered FUS-PARP-1-DNA Ligase III axis and its implications to nuclear and mitochondrial genome damage response in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

  Hegde, M., Hamilton, D. J., Horner, P. J., Mitra, J. & Wang, H.

  4/15/20 → 3/31/25

  Project: Federal Funding Agencies

• Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease

  Masdeu, J. C.

  9/30/20 → 4/30/25

  Project: Federal Funding Agencies

• Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered Vein-Chip.

  Cooke, J. P.

  5/1/21 → 4/30/25

  Project: Federal Funding Agencies

• Prospective Sudden Cardiac Death Risk Stratification Using Cardiac MRI and Echocardiography Machine Learning in Mitral Valve Prolapse.

  Shah, D. J.

  5/26/20 → 4/30/25

  Project: Federal Funding Agencies

• VENOUS: A translational study of enterococcal bacteremia

  Arias, C. A.

  6/1/22 → 5/31/25

  Project: Federal Funding Agencies

• Convergent AI for Precise Breast Cancer Risk Assessment

  Wong, S. T., Chang, J. C. & Ensor, Jr., J. E.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Influence of pre-analytical factors in glioblastoma MGMT promoter methylation biomarker assay

  Rostomily, R. C., Mitra, S. & Powell, S. Z.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining its contributions to post-transcriptional gene regulation

  Kiss, D. L.

  8/15/20 → 6/30/25

  Project: Federal Funding Agencies

• HEALEY ALS Platform Trial - Regimen-Specific Appendix A - For 0.3mh/kg SC zilucoplan administered once daily and placebo

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  7/24/20 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix B - For verdiperstat (also known as BHV-3241)

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  7/24/20 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix D - For pridopidine 45 mg oral capsule administered twice daily (BID) or its matching placebo.

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  6/29/21 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix C - For CNM-Au8

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  7/24/20 → 7/23/25

  Project: Non Profit

• Elucidating spinal sensorimotor network components that underlie recovery of motor functions via lumbosacral epidural electrical stimulation in humans with spinal cord injury

  Sayenko, D.

  8/15/20 → 7/31/25

  Project: Federal Funding Agencies