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• VAS-WRAPSODY Endovascular Stent Graft for Hemodialysis Patients Merit Medical

  Peden, E. K., Le, L., Rahimi, M. & Roy, T.

  7/30/21 → …

  Project: Clinical Trial

• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Compare the Efficacy and Safety of Sotatercept Versus Placebo When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH_A011-11 (STELLAR)

  Safdar, Z. & Sahay, S.

  7/30/21 → …

  Project: Clinical Trial

• A Randomized, Double-Blind, Placebo-Controlled, Two-Part Study in Parkinson's Disease Patients With Dyskinesia to Assess the Efficacy and Safety/Tolerability of Fixed Dose Combinations of JM-010 and Its Individual Components

  Waln, O. & Ondo, W. G.

  7/30/21 → …

  Project: Clinical Trial

• A Double-Blind, Placebo-Controlled, Randomized, 18-Month Phase 2a Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Oral UCB0599 in Study Participants With Early Parkinson's Disease

  Waln, O. & Ondo, W. G.

  7/23/21 → …

  Project: Clinical Trial

• Understanding the long term impact of COVID-19 on the brain through advanced MR imaging and spectroscopy

  Ashizawa, T. & Karmonik, C.

  7/15/21 → 6/30/22

  Project: Federal Funding Agencies

• Fulvestrant Plus Abemaciclib With or Without Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer

  Chang, J. C. & Niravath, P. A.

  7/15/21 → …

  Project: Clinical Trial

• A Randomized Placebo-controlled Trial of Zoledronic Acid for Prevention of Fractures in Patients with Parkinson¿s Disease

  Waln, O. & Ondo, W. G.

  7/14/21 → 7/13/23

  Project: Non Profit

• Sepsis Prediction with Deep Learning and Wearable Monitoring Patch'd

  Pingali, S. R., Ganguly, S., Gotur, D. B., Jones, S. L., Masud, F. N. & Shah, S.

  7/14/21 → …

  Project: Clinical Trial

• A Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Volixibat in the Treatment of Cholestatic Pruritus in Patients with Primary Sclerosing Cholangitis (VISTAS)

  Victor, III, D. W. & Kodali, S.

  7/9/21 → …

  Project: Clinical Trial

• NeoSoma Neuro-oncology AI Platform

  Fung, S. H. & Baskin, D. S.

  7/7/21 → …

  Project: Clinical Trial

• Targeting the HIV-1 Reservoir in Myeloid Cells

  Wang, J.

  7/6/21 → 5/31/26

  Project: Federal Funding Agencies

• A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL, ACTIVE-CONTROLLED STUDY OF TRASTUZUMAB DERUXTECAN (T-DXd) VERSUS TRASTUZUMAB EMTANSINE (T-DM1) IN SUBJECTS WITH HIGH-RISK HER2-POSITIVE PRIMARY BREAST CANCER WHO HAVE RESIDUAL INVASIVE DISEASE IN BREAST OR

  7/6/21 → 7/5/31

  Project: Non Profit

• Engineered Enteric Nervous System-Peri Neural Invasion platform to improve predictive preclinical screens in early-stage colorectal adenocarcinomas

  Esnaola, N. F.

  7/1/21 → 6/30/23

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining its contributions to post-transcriptional gene regulation (Same as parent grant)

  Kiss, D. L.

  7/1/21 → 6/30/23

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining itscontributions to post-transcriptional gene regulation (Same as parent grant)

  Kiss, D. L.

  7/1/21 → 6/30/25

  Project: Federal Funding Agencies

• A versatile reporter for visualization of myelin plasticity in the genetically modified rat

  Horner, P. J.

  7/1/21 → 12/31/23

  Project: Federal Funding Agencies

• HEALEY ALS Platform Trial - Regimen-Specific Appendix D - For pridopidine 45 mg oral capsule administered twice daily (BID) or its matching placebo.

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  6/29/21 → 7/23/25

  Project: Non Profit

• SH:HighLife Transseptal Transcatheter Mitral Valve Replacement HighLife Medical

  Goel, S., Faza, N., Kleiman, N., Little, S. H. & Reardon, M. J.

  6/29/21 → …

  Project: Clinical Trial

• MERCK MK-5475 in PAH, Phase 23 A Phase 2/3, Multicenter, Randomized, Double-blind, Placebo-Controlled, Adaptive Design Study to Evaluate the Efficacy and Safety of MK-5475 in Adults With Pulmonary Arterial Hypertension

  Sahay, S. & Safdar, Z.

  6/28/21 → …

  Project: Clinical Trial

• AOCT - Intuitive da Vinci SP in Colorectal Surgical Procedures

  6/28/21 → …

  Project: Clinical Trial

• SH-REPAIR MR - Mitraclip Device vs. Surgical Repair for Mitral Regurgitation Abbott Percutaneous MitraClipTM Device or Surgical Mitral Valve REpair in PAtients with PrImaRy Mitral Regurgitation who are Candidates for Surgery (REPAIR MR)

  Goel, S., Bhimaraj, A., Faza, N., Guha, A., Kassi, M., Kleiman, N., Lawrie, G. M., Little, S. H., Reardon, M. J. & Yousefzai, R.

  6/28/21 → …

  Project: Clinical Trial

• Long-Term, Observational, Registry of Patients With Generalized Myasthenia Gravis Who Have Received Treatment With Complement C5 Inhibition Therapies

  Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  6/28/21 → …

  Project: Clinical Trial

• High-speed biophysical and biochemical monitoring to discover early markers of unconventional brain injury

  Villapol, S.

  6/16/21 → 9/15/22

  Project: Federal Funding Agencies

• Mitochondrial function in symptomatic chronic COVID-19 patients COVID-19 Associated Mitochondria Functional Changes in Subjects with Post-Acute Sequelae of SARS-CoV-2 Infections (PASC)

  Hamilton, D. J., Kansara, A. & Youssef, J. G.

  6/16/21 → …

  Project: Clinical Trial

• Assessing Energy Needs, Nutritional Status, and Physical Functioning in Patients with Hepatocellular Carcinoma (HCC)

  Kodali, S.

  6/7/21 → …

  Project: Clinical Trial

• Molecular Mechanism of Virulence Regulation in Streptococcus Pyogenes

  Kumaraswami, M. & Olsen, R. J.

  6/7/21 → 5/31/26

  Project: Federal Funding Agencies

• Studies of a new checkpoint regulator in the control of intestinal inflammation

  Zhang, Z. & Li, X. C.

  6/7/21 → 5/31/26

  Project: Federal Funding Agencies

• A Randomized, Open-Label, Phase 3 Study Evaluating Efficacy and Safety of Navitoclax in Combination With Ruxolitinib Versus Best Available Therapy in Subjects With Relapsed/Refractory Myelofibrosis (TRANSFORM-2)

  Shah, S., Ganguly, S., Pingali, S. R. & Rice, L.

  6/7/21 → …

  Project: Clinical Trial

• Novel Stem Cell Immunotherapy for MDR-Tuberculosis

  Jagannath, C.

  6/4/21 → 5/31/26

  Project: Federal Funding Agencies

• Recovery and Outcomes from StrokE

  Vahidy, F. S.

  6/1/21 → 4/30/23

  Project: Federal Funding Agencies

• The immunosuppressive function of secretory IgM in tumor-bearing mice

  Tang, C. A. & Yin, Z.

  6/1/21 → 5/31/24

  Project: Federal Funding Agencies

• Novel Determinants of Streptococcus Pyogenes Virulence and Protective Immunity in the Primate Oropharynx: A Genome-wide Strategy

  Musser, J. M., Nagueh, S. & Olsen, R. J.

  6/1/21 → 5/31/22

  Project: Federal Funding Agencies

• A Novel M2 Lipogenic Macrophage Associated with Fracture Callus are Altered in Type 2 Diabetes

  Davis, B.

  6/1/21 → 5/31/23

  Project: Federal Funding Agencies

• Converting HR Breast Cancer Into an Individualized Vaccine

  Chang, J. C. & Niravath, P. A.

  5/26/21 → …

  Project: Clinical Trial

• Potentiation of Multi-peptide Lung Cancer Vaccines with Immune Checkpoint Antagonist CA-170

  You, M. & Yi, Q.

  5/24/21 → 11/23/23

  Project: Federal Funding Agencies

• Houston Alzheimer Disease Study

  Masdeu, J. C., Faridar, A., Fujita, M., Karmonik, C., Nakawah, M. O., Pascual, B., Roman, G. C., Toledo, J. B. & Wong, S. T.

  5/17/21 → …

  Project: Clinical Trial

• Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer¿s Disease

  Wong, S. T., Sheng, J. & Yin, Z.

  5/15/21 → 4/30/26

  Project: Federal Funding Agencies

• Lung Microphysiological Systems to Model Select Agent Bacteria and Viral Infection and Test Candidate Countermeasures

  Nichols, J.

  5/13/21 → 4/4/22

  Project: Federal Funding Agencies

• CVL-751-PD-004 (TEMPO-1 TRIAL)

  Ondo, W. G. & Waln, O.

  5/11/21 → …

  Project: Clinical Trial

• EGFR and KRAS Vaccine to Prevent Lung Cancer

  Wang, Y. & You, M.

  5/10/21 → 8/31/23

  Project: Federal Funding Agencies

• E01 - Further Testing of a Multi-Peptide KRASE Vaccine for Pancreatic Cancer Prevention

  You, M., Wang, Y. & Xiong, D.

  5/10/21 → 8/20/22

  Project: Federal Funding Agencies

• E02 - Chemoprevention with Aerosolized Let-7 microRNA in Mouse Models of Non-Small Cell Lung Cancer

  Wang, Y., You, M., Xiong, D. & Zhang, Q.

  5/10/21 → 8/27/22

  Project: Federal Funding Agencies

• African trypanosome parasites: a new tool to unveil potential immunological strategies totarget CLL

  Hu, C. A.

  5/3/21 → 4/30/23

  Project: Federal Funding Agencies

• Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered Vein-Chip.

  Cooke, J. P.

  5/1/21 → 4/30/25

  Project: Federal Funding Agencies

• Upper Extremity Nerve Transfers in Spinal Cord Injury Patients

  Faraji, A.

  5/1/21 → 9/29/22

  Project: Federal Funding Agencies

• BO41843: Phase III_GDC-9545 RO7197597_Breast Cancer_Roche BO41843: A Phase III Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Efficacy and Safety of GDC-9545 Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Patients With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer

  Niravath, P. A. & Chang, J. C.

  4/28/21 → …

  Project: Clinical Trial

• EP-CATALYST - Amulet Device Compared to NOACs for A-Fib Treatment Abbott

  Valderrábano, M., Dave, A., Goel, S., Lador, A., Mathuria, N. & Schurmann, P. A.

  4/19/21 → …

  Project: Clinical Trial

• GOG-3044 LAE002INT2001

  Kamat, A. A., Alaniz, A., Singh, M., Suri, A. & Zaid, T.

  4/16/21 → …

  Project: Clinical Trial

• TB/MDR-TB research Capacity Building in LMIC in Southeast Asia

  Graviss, E. A.

  4/1/21 → 2/28/23

  Project: Federal Funding Agencies

• A Phase II and Biomarker Study of Dual VEGF/PD-L1 Blockade in Neoadjuvant Setting in Resectable Hepatocellular Carcinoma Patients

  Ghobrial, R. M., Abdelrahim, M. & Kodali, S.

  4/1/21 → 3/31/26

  Project: Federal Funding Agencies