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• A prospective, multi-center, observational study of the safety, tolerability and effectiveness of SPINRAZA in adult patients with Spinal Muscular Atr

  Thonhoff, J. R., Greene, E. P. & Shroff, S.

  5/10/19 → …

  Project: Clinical Trial

• A Prospective, Multicenter Study to Evaluate the ConforMIS iTotal® (CR) Knee Replacement System

  11/23/16 → …

  Project: Clinical Trial

• A Prospective, Randomized, Multi-center, Single-Blinded, Placebo-Controlled, 3-Arm Clinical Study to Assess the Efficacy and Safety of Vibrant Capsule, for the Treatment of Chronic Idiopathic Constipation

  Quigley, E. M.

  6/28/19 → …

  Project: Clinical Trial

• A Prospective Registry Study to Evaluate the Effect of the DCISionRT Test on Treatment Decisions in Patients With DCIS Following Breast Conserving Therapy

  Templeton, S., Arentz, C., Chang, J. C., Darcourt, J., Dubrovsky, E., Haque, W. M., Heyne, K., Morgan, P. B., Niravath, P. A. & Singh, M.

  12/16/19 → …

  Project: Clinical Trial

• A Randomized, Double-blind, Phase 3 Comparison of Platinum-based Therapy With TSR-042 and Niraparib Versus Standard of Care Platinum-based Therapy as First-line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer (ENGOT-0V44 The FIRST)

  Suri, A., Alaniz, A., Darcourt, J., Singh, M. & Zaid, T.

  7/30/19 → …

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo

  Niravath, P. A., Abdelrahim, M., Arentz, C., Chang, J. C., Darcourt, J., Geyer, C. E., Heyne, K. & Singh, M.

  6/16/20 → …

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab With Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Chang, J. C., Darcourt, J., Geyer, C. E. & Niravath, P. A.

  5/19/20 → …

  Project: Clinical Trial

• A Randomized, Multicenter, Phase 2 Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab Versus Bevacizumab Alone in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy (NCT03149003)

  Baskin, D. S. & Bernicker, E. H.

  2/28/18 → …

  Project: Clinical Trial

• A Randomized, Open-label, Phase II Study of Canakinumab or Pembrolizumab as Monotherapy or in Combination as Neoadjuvant Therapy in Subjects With Resectable Non-small Cell Lung Cancer (CANOPY-N)

  Bernicker, E. H., Barrios, R., Chan, E. Y., Chang, J. C., Darcourt, J., Heyne, K., Kim, M. P., Niravath, P. A., Singh, M. & Zhang, J.

  4/9/20 → …

  Project: Clinical Trial

• A Randomized, Open-Label Extension Study to Investigate the Long-Term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

  Shroff, S., Appel, S. H., Greene, E. P. & Thonhoff, J. R.

  4/23/20 → …

  Project: Clinical Trial

• A Randomized, Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer With ? 1 CM Residual Invasive Cancer or Positive Lymph Nodes (ypN+) After Neoadjuvant Chemotherapy

  Niravath, P. A., Bernicker, E. H., Chang, J. C., Darcourt, J., Geyer, C. E., Heyne, K., Morgan, P. B. & Singh, M.

  3/1/18 → …

  Project: Clinical Trial

• A Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D in premenopausal Women at High Risk for Breast Cancer

  Rodriguez, A. A., Chang, J. C., Singh, M. & Lehane, D. E.

  University of Michigan

  6/29/12 → 3/22/37

  Project: Federal Funding Agencies

• A Randomized Factorial-Design Phase II Trial of Temozolomide in Combination with possible Permutations of Thalidomide Isotretinoin and/or Celecoxib as Post-Radiation Adjuvant of Glioblastoma Mutiforme

  Univ of Texas MD Anderson Cancer Center

  1/6/10 → 1/5/12

  Project: Non Profit

• A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative

  Niravath, P. A., Bernicker, E. H., Butler, E. B., Chang, J. C., Darcourt, J., Farach, A. M., Haque, W. M., Heyne, K., Morgan, P. B., Shkedy, C. & Teh, B. S.

  1/11/17 → …

  Project: Clinical Trial

• A RANDOMIZED PHASE III DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OFASPIRIN AS ADJUVANT THERAPY FOR HER2 NEGATIVE BREAST CANCER: THE ABCTRIAL

  Arentz, C., Abdelrahim, M., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  12/8/16 → 12/7/41

  Project: Non Profit

• A Randomized Phase III Trial of Radiation Therapy and Cisplatin Alone or in Combination With Intravenous Triapine in Women With Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer (NRG-GY006)

  Zaid, T., Alaniz, A., Butler, E. B., Darcourt, J., Farach, A. M., Haque, W. M., Kamat, A. A., Morgan, P. B., Shadle, K. M., Shkedy, C., Singh, M. & Suri, A.

  2/22/19 → …

  Project: Clinical Trial

• A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination withIntravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2

  Zaid, T., Butler, E. B., Darcourt, J., Farach, A. M., Kamat, A. A., Shkedy, C., Singh, M., Suri, A. & Lehane, D. E.

  3/1/14 → 2/28/39

  Project: Non Profit

• ARCADIA

  Misra, V., Gadhia, R. R. & Volpi, J. J.

  8/8/18 → …

  Project: Clinical Trial

• ARCADIA: Atrial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke

  Misra, V., Gadhia, R. R. & Volpi, J. J.

  5/1/17 → 4/30/23

  Project: Non Profit

• A Registry for Patients Taking Uptravi (SPHERE)

  Safdar, Z. & Sahay, S.

  1/11/17 → …

  Project: Clinical Trial

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  Pascual, B., Faridar, A. & Masdeu, J. C.

  9/15/19 → 6/30/24

  Project: Non Profit

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) - Clinical Core

  Pascual, B. & Masdeu, J. C.

  9/15/19 → 6/30/21

  Project: Federal Funding Agencies

• A simple assay system for rapid detection of circulating tumor cells.

  Zu, Y. & Chang, J. C.

  TeloVISION, LLC

  9/25/14 → 9/24/16

  Project: Federal Funding Agencies

• ASPEN- OLE

  Ondo, W. G. & Waln, O.

  1/3/19 → …

  Project: Clinical Trial

• Assessing CSF flow in glymphatics

  Britz, G. W., Golanov, E. V. & Karmonik, C.

  2/5/20 → …

  Project: Clinical Trial

• Assessing Energy Needs, Nutritional Status, and Physical Functioning in Patients with Hepatocellular Carcinoma (HCC)

  Project: Clinical Trial

• Assessing QFT as an Initial Screening Tool for U.S.-Bound Applicants for Immigration and Feasibility of Follow-up in U.S. Immigrants

  Graviss, E. A.

  Denver Health and Hospital Authority

  12/5/08 → 9/27/11

  Project: Federal Funding Agencies

• Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery

  Niravath, P. A., Bernicker, E. H., Chang, J. C., Darcourt, J. & Singh, M.

  1/30/18 → …

  Project: Clinical Trial

• Assessment of Breast Cancer Mechanopathology Markers Using Ultrasound

  Taraballi, F., Patel, T. & Peterson, L. E.

  8/15/19 → 8/14/21

  Project: Federal Funding Agencies

• Assessment of Spinal Injuries Using Novel Ultrasound Techniques

  Weiner, B. K. & Tasciotti, E.

  Texas AandM University

  9/30/14 → 9/29/19

  Project: Federal Funding Agencies

• Association of LVAD inflow cannula position with the development of acquired VWD and altered angiogenesis

  Kassi, M., Bhimaraj, A., Graviss, E. A., Guha, A., Hussain, I., Kim, J. H., Trachtenberg, B. H. & Youker, K. A.

  10/30/19 → …

  Project: Clinical Trial

• A Stereotactic Atlas of the Human Spinal Cord

  Grossman, R. G.

  10/1/16 → 9/30/18

  Project: Non Profit

• Astrocyte-Specific Ligand Discovery by Phage Display

  Horner, P. J.

  2/1/17 → 1/31/19

  Project: Federal Funding Agencies

• Astroparticles: A Human Astrocyte-Based Nanotechnology for Neuroregeneration

  Krencik, R. C.

  10/24/19 → 10/23/21

  Project: Non Profit

• A Study of Zolbetuximab Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin 18.2-Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

  Abdelrahim, M., Bernicker, E. H., Darcourt, J., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  5/16/19 → …

  Project: Clinical Trial

• A Study to Assess the Antitumor Activity and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

  Abdelrahim, M., Bernicker, E. H., Chang, J. C., Darcourt, J., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  11/7/19 → …

  Project: Clinical Trial

• A Study to Evaluate the Effectiveness and Safety of ExAblate Transcranial MRgFUS Thalamotomy Treatment of Medication Refractory Essential Tremor Subjects.

  Ondo, W. G.

  12/1/15 → 4/30/17

  Project: Non Profit

• A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302)

  Abdelrahim, M., Bernicker, E. H., Chang, J. C., Darcourt, J., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  8/23/19 → …

  Project: Clinical Trial

• Atara Registry - ATA129-RS002 (PO# P04279-1)

  Goodarzi, A. & Yau, S. W.

  2/3/20 → …

  Project: Clinical Trial

• A Targeted Nanomedicine Prototype Against Enzalutamide-resistant Prostate Cancer

  Cristini, V. & Wang, Z.

  8/1/18 → 7/31/23

  Project: Federal Funding Agencies

• Atezo and IL-12 NSCLC

  Bernicker, E. H., Chan, E. Y., Darcourt, J., Heyne, K., Kim, M. P., Singh, M., Sultenfuss, M. A. & Zhang, J.

  Project: Clinical Trial

• Atezolizumab IIS

  Esnaola, N. F., Bernicker, E. H., Chen, S. & Darcourt, J.

  12/19/19 → …

  Project: Clinical Trial

• Atheroprotection via Reduced Plasma High Density Lipoprotein-Free Cholesterol Bioavailability

  Pownall, H. J., Rosales, C. & Gillard, B. K.

  12/1/19 → 11/30/23

  Project: Federal Funding Agencies

• Atheroregression via Enhanced Reverse Cholesterol Transport

  Pownall, H. J. & Gillard, B. K.

  National Heart Lung and Blood Institute

  4/20/13 → 12/31/16

  Project: Federal Funding Agencies

• ATLAS

  Klucznik, R. P., Britz, G. W., Diaz, O. M. & Zhang, Y. J.

  8/12/15 → …

  Project: Clinical Trial

• A tunable delivery platform for in vivo investigation of therapeutics

  Grattoni, A.

  Natl Inst of General Medical Sciences

  8/15/14 → 6/30/17

  Project: Federal Funding Agencies

• A tunable nanofluidic drug delivery platform for in vivo research

  Grattoni, A. & Liu, X.

  4/15/18 → 1/31/22

  Project: Federal Funding Agencies

• A unique microbial signature drives the development of non alcoholic fatty liver disease in patients with inflammatory bowel disease

  Abraham, B. P., Glassner, K., Quigley, E. M. & Victor, III, D. W.

  10/24/19 → …

  Project: Clinical Trial

• Avelumab and IL-12 NSCLC

  Bernicker, E. H., Chan, E. Y., Darcourt, J., Heyne, K., Kim, M. P., Singh, M., Sultenfuss, M. A. & Zhang, J.

  Project: Clinical Trial

• B43 Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy

  Niravath, P. A., Chang, J. C., Darcourt, J., Singh, M. & Teh, B. S.

  12/5/14 → …

  Project: Clinical Trial