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• Outcome-Driven Approach to Minimize the Risks of Facial Distortion Following CMF Surgery

  Xia, J. J. & Gateno, J.

  8/1/20 → 7/31/25

  Project: Federal Funding Agencies

• CPRIT RNA Therapeutics Core

  Cooke, J. P., Godin, B. & Kiss, D. L.

  8/31/20 → 8/30/25

  Project: State

• Spatiotemporal modeling of cancer-niche interactions in breast cancer bone metastasis

  Wong, S. T., Chang, J. C. & Sheng, J.

  9/15/20 → 8/31/25

  Project: Federal Funding Agencies

• Control of dysfunctional Tregs

  Li, X. C. & Xiao, J.

  2/1/14 → 1/31/26

  Project: Federal Funding Agencies

• S100A4 mediated immune suppression in GBM

  Yun, K. & Xu, S.

  4/1/21 → 1/31/26

  Project: Federal Funding Agencies

• Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer

  Wang, Z. & Cristini, V.

  3/4/21 → 2/28/26

  Project: Federal Funding Agencies

• NSABP43; NSABP47; ECOG 2108

  Chang, J. C.

  "NSABP Foundation, Inc"

  3/1/11 → 3/25/26

  Project: Non Profit

• A Phase II and Biomarker Study of Dual VEGF/PD-L1 Blockade in Neoadjuvant Setting in Resectable Hepatocellular Carcinoma Patients

  Ghobrial, R. M., Abdelrahim, M. & Kodali, S.

  4/1/21 → 3/31/26

  Project: Federal Funding Agencies

• Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer¿s Disease

  Wong, S. T., Sheng, J. & Yin, Z.

  5/15/21 → 4/30/26

  Project: Federal Funding Agencies

• Molecular Mechanism of Virulence Regulation in Streptococcus Pyogenes

  Kumaraswami, M. & Olsen, R. J.

  6/7/21 → 5/31/26

  Project: Federal Funding Agencies

• Studies of a new checkpoint regulator in the control of intestinal inflammation

  Zhang, Z. & Li, X. C.

  6/7/21 → 5/31/26

  Project: Federal Funding Agencies

• Novel Stem Cell Immunotherapy for MDR-Tuberculosis

  Jagannath, C. & Khan, A.

  6/4/21 → 5/31/26

  Project: Federal Funding Agencies

• Targeting the HIV-1 Reservoir in Myeloid Cells

  Wang, J.

  7/6/21 → 5/31/26

  Project: Federal Funding Agencies

• A novel tool in high- dimensional single-cell space to predict neurotoxicity of CAR T cell therapies

  Lu, Y.

  8/1/21 → 7/31/26

  Project: Federal Funding Agencies

• Contemporary Classification of Myocardial Injury Events in MESA: Defining Distinct Risk Factor Associations with Myocardial Infarction Type 1-5 and Acute Non-Ischemic Myocardial Injury.

  Nasir, K.

  8/20/21 → 7/31/26

  Project: Federal Funding Agencies

• CPRIT Scholar Application - Rising Star - Yong Lu

  Lu, Y.

  8/31/21 → 8/30/26

  Project: State

• Harnessing neuroplasticity of postural sensorimotor networks using non-invasive spinal neuromodulation to maximize functional recovery after spinal cord injury

  Sayenko, D., Barber, S., Horner, P. J., Kaldis, T. & Vahidy, F. S.

  12/1/21 → 11/30/26

  Project: Federal Funding Agencies

• XBP1 Inhibition and STING activation for the treatment of cancer

  Hu, A.

  4/8/22 → 3/31/27

  Project: Federal Funding Agencies

• Mechanisms driving cardiac dysfunction in Autosomal Dominant Polycystic Kidney Disease

  Altamirano, F.

  5/15/22 → 4/30/27

  Project: Federal Funding Agencies

• Ultra-long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure

  Grattoni, A.

  6/1/22 → 5/31/27

  Project: Federal Funding Agencies

• Development of therapeutic mRNA vaccine

  6/28/17 → 6/28/27

  Project: Non Profit

• A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL, ACTIVE-CONTROLLED STUDY OF TRASTUZUMAB DERUXTECAN (T-DXd) VERSUS TRASTUZUMAB EMTANSINE (T-DM1) IN SUBJECTS WITH HIGH-RISK HER2-POSITIVE PRIMARY BREAST CANCER WHO HAVE RESIDUAL INVASIVE DISEASE IN BREAST OR

  7/6/21 → 7/5/31

  Project: Non Profit

• Multicenter Screening Trial of Safety and Efficacy of Lithium Carbonate in ALS (MDA 105838)

  Greene, E. P.

  California Pacific Medical Ctr Res Inst

  3/1/08 → 7/17/35

  Project: Non Profit

• The VICTORIA Multi-Center Clincial Registery: Visual Interpretation of Completeness and Technical Operative Results using Intra-operative Arteriography in Coronary Artery Bypass Surgery

  East Carolina University

  10/20/08 → 3/6/36

  Project: Non Profit

• Treatment of Preserved Cardiac function heart failure with an Aldosterone an Tagonist (TOPCAT)

  Kurrelmeyer, K. M.

  New England Research Institutes Inc

  3/27/09 → 8/11/36

  Project: Non Profit

• A Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D in premenopausal Women at High Risk for Breast Cancer, Phase IIB

  Chang, J. C. & Singh, M.

  University of Michigan

  6/29/12 → 3/22/37

  Project: Federal Funding Agencies

• Gaining Efficacy Long Term:Hydrosoft and Emerging New Embolic Coil (Gel-the-nec)

  Mayo Clinic

  1/18/10 → 6/4/37

  Project: Non Profit

• Clinical Evaluation of Therapy Cool Path Duo Cardiac Ablation System For the Treatment of Typical Atrial Flutter (Duo FLAIR) Study

  Valderrábano, M.

  St. Jude Medical

  2/8/10 → 6/25/37

  Project: Non Profit

• Prospective multi-center randomized double-blind trial to assess the effectiveness and safety of 12 vs 30 months of dual antiplatelet therapy (DAPT) in subjects undergoing percutaneous coronary intervention (PCI) with either drug-eluting (DES) or bar

  Kleiman, N.

  Harvard Clinical Research Institute

  6/30/10 → 11/14/37

  Project: Non Profit

• TrialNet Natural History Study of the Development of Type 1 Diabetes

  University of South Florida

  9/13/10 → 1/28/38

  Project: Federal Funding Agencies

• Escalating Clopidogrel by Involving a Genetic Strategy (ELEVATE-TIMI 56)

  Kleiman, N.

  Brigham and Women's Hospital

  11/10/10 → 3/27/38

  Project: Non Profit

• Phase IIa Double-Blind, Placebo-Controlled Study to Evaluate the Safety ofOral Fingolimod in Patients with ALS

  Greene, E. P., Appel, S. H. & Lai, E. C.

  Massachusetts General Hospital

  5/13/13 → 5/12/38

  Project: Non Profit

• CAN DIET AND PHYSICAL ACTIVITY MODULATE OVARIAN, FALLOPIAN TUBE AND PRIMARY PERITONEAL CANCER PROGRESSION-FREE SURVIVAL?

  Kamat, A. A., Kaplan, A. L. & Singh, M.

  Gynecologic Oncology Group

  5/14/13 → 5/13/38

  Project: Non Profit

• A Phase II/III Trial of Neoadjuvant FOLFOX w/ Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection w/ Total Mesorectal Excisio

  Bernicker, E. H., Darcourt, J. & Singh, M.

  University of Michigan

  6/11/13 → 6/10/38

  Project: Non Profit

• A PHASE III TRIAL EVALUATING THE ADDITION OF TRASTUZUMAB TO TRIMODALITY TREATMENT OF HER2-OVEREXPRESSING ESOPHAGEAL ADENOCARCINOMA

  Butler, E. B., Kim, M. P. & Teh, B. S.

  University of Michigan

  7/24/13 → 7/23/38

  Project: Non Profit

• EUCLID - Examining Use of tiCagreLor In paD

  Duke University

  8/12/13 → 8/11/38

  Project: Non Profit

• EUCLID - Examining Use of tiCagreLor In paD

  Shah, A. R.

  Duke University

  8/12/13 → 8/11/38

  Project: Non Profit

• PHASE III RANDOMIZED STUDY OF SORAFENIB PLUS DOXORUBICIN VERSUS SORAFENIB IN PATIENTS WITH ADVANCED HEPATOCELLULAR CARCINOMA (HCC)

  Bernicker, E. H., Darcourt, J. & Singh, M.

  University of Michigan

  8/13/13 → 8/12/38

  Project: Non Profit

• GUP09-145(Bionomics);

  Preti, H. A. & Singh, M.

  Hoosier Oncology Group

  7/1/11 → 11/15/38

  Project: Non Profit

• RTOG-0834; RTOG-0913; RTOG-0929

  Radiation Therapy Oncology Group

  8/10/11 → 12/25/38

  Project: Federal Funding Agencies

• A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination withIntravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVACancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer.

  Zaid, T., Butler, E. B., Darcourt, J., Farach, A. M., Kamat, A. A., Shkedy, C., Singh, M. & Suri, A.

  3/1/14 → 2/28/39

  Project: Non Profit

• Colorectal Cancer Metastatic dMMR Immuno-Therapy (COMMIT) Study:A Randomized Phase III Study of mFOLFOX6/Bevacizumab Combination Chemotherapy with orwithout Atezolizumab or Atezolizumab Monotherapy in the First-Line Treatment of Patients withDefici

  Abdelrahim, M., Bernicker, E. H., Darcourt, J., Heyne, K. & Singh, M.

  3/1/14 → 2/28/39

  Project: Non Profit

• A Randomized, Phase II/III Study of Pegylated Liposomal Doxorubicin and CTEP-Supplied Atezolizumab (IND #134427) Versus Pegylated Liposomal Doxorubicin/Bevacizumab and CTEP-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin/Bevacizumab in P

  Kamat, A. A., Darcourt, J., Singh, M., Suri, A. & Zaid, T.

  3/1/14 → 2/28/39

  Project: Non Profit

• A pilot, phase IIb, randomized, multi-center trial of Argatroban in combination with recombinant tissue plasminogen activator for acute stroke (ARTSS-2).

  Volpi, J. J., Chiu, D. & Gadhia, R. R.

  U T Health Science Center at Houston

  11/26/14 → 11/25/39

  Project: Non Profit

• S1602, A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG-Naïve High-Grade Non-Muscle Invasive Bladder Cancer.

  Satkunasivam, R.

  2/16/15 → 2/15/40

  Project: Non Profit

• Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study

  Masdeu, J. C.

  7/14/16 → 7/13/41

  Project: Non Profit

• EAY131 - Molecular Analysis for Therapy Choice (MATCH)

  Bernicker, E. H., Chang, J. C., Darcourt, J., Heyne, K., Kamat, A. A., Pingali, S. R. & Singh, M.

  9/20/16 → 9/20/41

  Project: Federal Funding Agencies

• A RANDOMIZED PHASE III DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OFASPIRIN AS ADJUVANT THERAPY FOR HER2 NEGATIVE BREAST CANCER: THE ABCTRIAL

  Arentz, C., Abdelrahim, M., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  12/8/16 → 12/7/41

  Project: Non Profit

• NSABP B-51 A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary

  12/9/16 → 12/9/41

  Project: Non Profit

• PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, PARALLEL-GROUP, STUDY OF AB103 AS COMPARED TO PLACEBO IN PATIENTS WITH NECROTIZING SOFT TISSUE INFECTIONS (NSTI)

  Dhala, A., Martinez, S., Mobley, C. M. & Ochoa, R. A.

  6/20/17 → 6/19/42

  Project: Federal Funding Agencies