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• Convergent AI for Precise Breast Cancer Risk Assessment

  Wong, S. T., Chang, J. C. & Ensor, Jr., J. E.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Novel Therapeutic Strategies to Co-Target Undifferentiated Prostate Cancer (PCa) Stem Cells and Bulk PCa Cells

  6/1/20 → 5/31/22

  Project: Federal Funding Agencies

• LONGITUDINAL EARLY ONSET ALZHEIMER¿S DISEASE (LEADS) supplement

  Masdeu, J. C.

  6/1/20 → 5/31/23

  Project: Federal Funding Agencies

• Phase III Trial of Docetaxel vs. Docetaxel and Radium-223 for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

  Heyne, K., Singh, M. & Zhang, J.

  5/27/20 → …

  Project: Clinical Trial

• A Phase III, Multicenter, Open-Label, Extension Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow® Device plus Standard of Care in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post Single or Double Lung Transplantation (BT-L-CsA-303-FU (BOSTON-3))

  Huang, H. J., Goodarzi, A., Yau, S. W. & Youssef, J. G.

  5/27/20 → …

  Project: Clinical Trial

• Prospective Sudden Cardiac Death Risk Stratification Using Cardiac MRI and Echocardiography Machine Learning in Mitral Valve Prolapse.

  Shah, D. J.

  5/26/20 → 4/30/25

  Project: Federal Funding Agencies

• SH-AltaValve

  Reardon, M. J., Chang, S., Faza, N., Goel, S., Kleiman, N., Lawrie, G. M. & Little, S. H.

  5/19/20 → …

  Project: Clinical Trial

• A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

  Singh, M., Abdelrahim, M., Beinart, G. & Heyne, K.

  5/18/20 → …

  Project: Clinical Trial

• Bayou Greenways Health Impact Study

  Nasir, K.

  5/1/20 → 12/31/21

  Project: Non Profit

• Evaluation of immune responses to CD44-targeted nanovectors for designing a novel anti-tuberculosis host-directed therapy

  Godin, B., Jagannath, C. & Leonard, F.

  5/1/20 → 10/31/22

  Project: Federal Funding Agencies

• Registry for Neurological Endpoint Assessments among patients with Ischemic and Hemorrhagic Stroke (REINAH)

  Vahidy, F. S., Britz, G. W., Horner, P. J. & Misra, V.

  4/28/20 → …

  Project: Clinical Trial

• A PILOT RANDOMIZED CONTROLLED TRIAL OF DE NOVO BELATACEPT-BASED IMMUNOSUPPRESSION IN LUNG TRANSPLANTATION

  Huang, H. J., Goodarzi, A. & Yau, S. W.

  4/23/20 → …

  Project: Clinical Trial

• Voice Rest Adherence After Phonomicrosurgery

  Yiu, Y.

  4/20/20 → 3/31/23

  Project: Federal Funding Agencies

• DOD - Dehisced-Wound

  Oviedo, R. J.

  4/16/20 → …

  Project: Clinical Trial

• Biodegradability and Biocompatiblity of a Shape Memory Polymer Wrap to Improve Saphenous Vein Graft Patency in Peripheral and Coronary Artery Bypass Grafting Surgeries

  Peden, E. K., Cooke, J. P. & Karmonik, C.

  4/15/20 → 10/31/21

  Project: Federal Funding Agencies

• A new conditional TDP¿NLS knock-in mouse model generated using CRISPR/Cas9 technology to study the linkage of TDP-43 pathology to motor and cognitive defects in ALS, FTD and ADRD

  Hegde, M., Mitra, J. & Wang, H.

  4/15/20 → 2/28/23

  Project: Federal Funding Agencies

• Defining the altered FUS-PARP-1-DNA Ligase III axis and its implications to nuclear and mitochondrial genome damage response in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

  Hegde, M., Hamilton, D. J., Horner, P. J., Mitra, J. & Wang, H.

  4/15/20 → 3/31/25

  Project: Federal Funding Agencies

• Sample and Data Collection for Houston Methodist Cancer Center Research

  Chang, J. C., Bernicker, E. H., Darcourt, J., Heyne, K., Niravath, P. A. & Singh, M.

  4/9/20 → …

  Project: Clinical Trial

• Intraoperative Analytics and Enhanced Patient Outcomes

  Corr, S. J.

  4/5/20 → 5/4/21

  Project: Federal Funding Agencies

• Novel carbon nanozyme mechanisms for traumatic brain injury therapy

  Hegde, M.

  4/1/20 → 3/31/25

  Project: Federal Funding Agencies

• U.S. Study to Protect Brain Health through Lifestyle Intervention to Reduce Risk:Neuroimaging Ancillary Study

  Masdeu, J. C.

  4/1/20 → 6/30/23

  Project: Federal Funding Agencies

• Myotonic Dystrophy Compilation of Clinical Findings

  Greene, E. P., Appel, S. H., Ashizawa, T., Mathuria, N., Shroff, S. & Thonhoff, J. R.

  4/1/20 → …

  Project: Clinical Trial

• LEAP-012 - MERCK (7902-012, Site No. 0784) Safety and Efficacy of Lenvatinib (E7080 / MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable / Non-metastatic Hepatocellular Carcinoma (MK-7902-012 / E7080-G000-318 / LEAP-012)

  Kodali, S., Abdelrahim, M., Ghobrial, R. M., Gibbs, J. M., Heyne, K., Saharia, A., Shetty, A. & Victor, III, D. W.

  3/27/20 → …

  Project: Clinical Trial

• A Pilot Randomized Controlled Trial of De Novo Belatacept-Based Immunosuppression in Lung Transplantation

  Huang, H. J.

  3/26/20 → 3/25/45

  Project: Non Profit

• AOCT - COVID-19 Plasma Donation

  Castillo, B., Chen, J. & Leveque, C.

  3/26/20 → …

  Project: Clinical Trial

• Phase 2, Open-Label Safety and Efficacy Study of Telisotuzumab Vedotin (ABBV-399) in Subjects With Previously Treated c-Met+ Non-Small Cell Lung Cancer

  Bernicker, E. H., Heyne, K., Singh, M. & Zhang, J.

  3/24/20 → …

  Project: Clinical Trial

• Receptive Music Approach to Improve Agitation in Hospitalized Dementia Patients

  3/23/20 → 6/30/21

  Project: Non Profit

• Building Resilience in Caregivers of Trauma Survivors

  Fowler, C.

  3/15/20 → 9/29/22

  Project: Federal Funding Agencies

• Under EdWorkplace Violence Against Nurses Prevention Grant Program

  3/11/20 → 4/30/22

  Project: State

• Exercise Intervention for Strong and Fit Pediatric Fontan Patients (StrongFitFontan)

  Cooke, J. P.

  3/10/20 → 2/28/25

  Project: Federal Funding Agencies

• ALLIANCE A221602: OLANZAPINEWITH ORWITHOUT FOSAPREPITANT FOR THE PREVENTION OF CHEMOTHERAPY INDUCED NAUSEA AND VOMITING (CINV) IN PATIENTS RECEIVING HIGHLY EMETOGENIC CHEMOTHERAPY (HEC): A PHASE III RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

  Darcourt, J., Bernicker, E. H., Chang, J. C., Geyer, C. E., Heyne, K. & Niravath, P. A.

  3/6/20 → 3/5/45

  Project: Non Profit

• The COMPASSHER2 Trials (COMprehensive Use of Pathologic Response ASSessment to Optimize Therapy in HER2-Positive Breast Cancer): COMPASSHER2 Residual Disease (RD), A Double-Blinded, Phase III Randomized Trial of T-DM1 and Placebo Compared with T-DM1 and

  3/6/20 → 3/5/45

  Project: Non Profit

• INTEGRATION OF IMMUNOTHERAPY INTO ADJUVANT THERAPY FOR RESECTED NSCLC: ALCHEMIST CHEMO-IO (ACCIO)

  Bernicker, E. H. & Zhang, J.

  3/6/20 → 3/5/45

  Project: Non Profit

• CTSU - IRB SUBMISSIONA Phase III Trial To Evaluate The Efficacy Of The Addition Of Inotuzumab Ozogamicin (A Conjugated Anti-Cd22 Monoclonal Antibody) To Frontline Therapy In Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL.

  Abdelrahim, M., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  3/6/20 → 3/5/45

  Project: Non Profit

• Imaging the mechanical microenvironment in cancers using ultrasound

  Chua, C. Y. X. & Chang, J. C.

  3/1/20 → 2/28/23

  Project: Federal Funding Agencies

• A DNAzyme that targets the CAG repeat RNA in polyglutamine diseases

  3/1/20 → 2/28/21

  Project: Non Profit

• FDP Sub in - MESENCHYMAL STEM CELLS FOR THE TREATMENT OF MODERATE TO SEVERE COVID-19 ACUTE RESPIRATORY DISTRESS SYNDROME

  Zainab, A., Hsu, S. H., Masud, F. N. & Reardon, M. J.

  3/1/20 → 2/28/22

  Project: Federal Funding Agencies

• Molecular mechanism of streptococcal adaptation to host nutritional defenses

  Kumaraswami, M. & Olsen, R. J.

  2/25/20 → 1/31/25

  Project: Federal Funding Agencies

• Multicenter Phase II Trial of Durvalumab (MEDI4736) With Trastuzumab and Pertuzumab Combination in HER2-Enriched and HER2-Amplified Breast Cancer (DTP Trial)

  Chang, J. C. & Niravath, P. A.

  2/21/20 → …

  Project: Clinical Trial

• Ocrelizumab for Psychosis by Autoimmunity (OPA)

  Masdeu, J. C., Faridar, A., Nakawah, M. O., Pascual, B., Toledo, J. B. & Weinstein, B.

  2/20/20 → …

  Project: Clinical Trial

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Wong, S. T., Zhao, H., Rostomily, R. C. & Sheng, J.

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• Biophysical roles of pre-metastatic niche evolution on transport of circulating tumor cells

  Kojic, M., Liu, X. & Qin, L.

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• Mild Hypothermia and Acute Kidney Injury AKI in Liver Transplantation MHALT Trial

  Ghobrial, R. M., Lindberg, S., Mobley, C. M., Saharia, A. & Victor, III, D. W.

  2/10/20 → …

  Project: Clinical Trial

• Assessing CSF flow in glymphatics

  Britz, G. W., Golanov, E. V., Karmonik, C. & Regnier-Golanov, A.

  2/5/20 → …

  Project: Clinical Trial

• AOCT - Zephyr Valve Registry ZEVR

  Kopas, L.

  2/3/20 → …

  Project: Clinical Trial

• Role of integrin VLA-6 in suppression of bone formation in myeloma

  Yang, J.

  2/1/20 → 1/31/23

  Project: Federal Funding Agencies

• Regulation of Glycogen Synthase 3 pathway by Polycystin-1 in Cardiomyocytes

  Altamirano, F.

  2/1/20 → 1/31/21

  Project: Federal Funding Agencies

• Ultra High-Field MR Spectroscopy of Non-alcoholic fatty liver disease

  Victor, III, D. W., Ghobrial, R. M., Graviss, E. A., Gupta, N. & Karmonik, C.

  1/30/20 → …

  Project: Clinical Trial

• Improving Non-Invasive Diagnosis and Grading of Cartilage Defects in the Knee - Accuracy of Ultra High Field 7-Tesla MRI as Compared With Arthroscopy

  McCulloch, P., Gupta, N. & Harris, J. D.

  1/30/20 → …

  Project: Clinical Trial

• REDUCE PAS

  Lin, C. H., Chiu, D., Gadhia, R. R., Kleiman, N., Misra, V. & Volpi, J. J.

  1/28/20 → …

  Project: Clinical Trial