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• Influence of pre-analytical factors in glioblastoma MGMT promoter methylation biomarker assay

  Rostomily, R. C., Mitra, S. & Powell, S. Z.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining its contributions to post-transcriptional gene regulation (Same as parent grant)

  Kiss, D. L.

  6/1/22 → 6/30/25

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining its contributions to post-transcriptional gene regulation

  Kiss, D. L.

  8/15/20 → 6/30/25

  Project: Federal Funding Agencies

• HEALEY ALS Platform Trial - Regimen-Specific Appendix B - For verdiperstat (also known as BHV-3241)

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  7/24/20 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix A - For 0.3mh/kg SC zilucoplan administered once daily and placebo

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  7/24/20 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix C - For CNM-Au8

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  7/24/20 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix D - For pridopidine 45 mg oral capsule administered twice daily (BID) or its matching placebo.

  Appel, S. H., Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  6/29/21 → 7/23/25

  Project: Non Profit

• Elucidating spinal sensorimotor network components that underlie recovery of motor functions via lumbosacral epidural electrical stimulation in humans with spinal cord injury

  Sayenko, D.

  8/15/20 → 7/31/25

  Project: Federal Funding Agencies

• Outcome-Driven Approach to Minimize the Risks of Facial Distortion Following CMF Surgery

  Xia, J. J. & Gateno, J.

  8/1/20 → 7/31/25

  Project: Federal Funding Agencies

• CPRIT RNA Therapeutics Core

  Cooke, J. P., Godin, B. & Kiss, D. L.

  8/31/20 → 8/30/25

  Project: State

• Spatiotemporal modeling of cancer-niche interactions in breast cancer bone metastasis

  Wong, S. T., Chang, J. C. & Sheng, J.

  9/15/20 → 8/31/25

  Project: Federal Funding Agencies

• Control of dysfunctional Tregs

  Li, X. C. & Xiao, J.

  2/1/14 → 1/31/26

  Project: Federal Funding Agencies

• S100A4 mediated immune suppression in GBM

  Yun, K. & Xu, S.

  4/1/21 → 1/31/26

  Project: Federal Funding Agencies

• Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer

  Wang, Z. & Cristini, V.

  3/4/21 → 2/28/26

  Project: Federal Funding Agencies

• NSABP43; NSABP47; ECOG 2108

  Chang, J. C.

  "NSABP Foundation, Inc"

  3/1/11 → 3/25/26

  Project: Non Profit

• A Phase II and Biomarker Study of Dual VEGF/PD-L1 Blockade in Neoadjuvant Setting in Resectable Hepatocellular Carcinoma Patients

  Ghobrial, R. M., Abdelrahim, M. & Kodali, S.

  4/1/21 → 3/31/26

  Project: Federal Funding Agencies

• Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer¿s Disease

  Wong, S. T., Sheng, J. & Yin, Z.

  5/15/21 → 4/30/26

  Project: Federal Funding Agencies

• Novel Stem Cell Immunotherapy for MDR-Tuberculosis

  Jagannath, C. & Khan, A.

  6/4/21 → 5/31/26

  Project: Federal Funding Agencies

• Targeting the HIV-1 Reservoir in Myeloid Cells

  Wang, J.

  7/6/21 → 5/31/26

  Project: Federal Funding Agencies

• Studies of a new checkpoint regulator in the control of intestinal inflammation

  Zhang, Z. & Li, X. C.

  6/7/21 → 5/31/26

  Project: Federal Funding Agencies

• Molecular Mechanism of Virulence Regulation in Streptococcus Pyogenes

  Kumaraswami, M. & Olsen, R. J.

  6/7/21 → 5/31/26

  Project: Federal Funding Agencies

• POR and Training Program on Multidrug-Resistant Organisms

  Arias, C. A.

  7/1/22 → 6/30/26

  Project: Federal Funding Agencies

• A novel tool in high- dimensional single-cell space to predict neurotoxicity of CAR T cell therapies

  Lu, Y.

  8/1/21 → 7/31/26

  Project: Federal Funding Agencies

• Contemporary Classification of Myocardial Injury Events in MESA: Defining Distinct Risk Factor Associations with Myocardial Infarction Type 1-5 and Acute Non-Ischemic Myocardial Injury.

  Nasir, K.

  8/20/21 → 7/31/26

  Project: Federal Funding Agencies

• CPRIT Scholar Application - Rising Star - Yong Lu

  Lu, Y.

  8/31/21 → 8/30/26

  Project: State

• Harnessing neuroplasticity of postural sensorimotor networks using non-invasive spinal neuromodulation to maximize functional recovery after spinal cord injury

  Sayenko, D., Barber, S., Horner, P. J., Kaldis, T. & Vahidy, F. S.

  12/1/21 → 11/30/26

  Project: Federal Funding Agencies

• XBP1 Inhibition and STING activation for the treatment of cancer

  Hu, A.

  4/8/22 → 3/31/27

  Project: Federal Funding Agencies

• Mechanisms driving cardiac dysfunction in Autosomal Dominant Polycystic Kidney Disease

  Altamirano, F.

  5/15/22 → 4/30/27

  Project: Federal Funding Agencies

• Ultra-long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure

  Grattoni, A.

  6/1/22 → 5/31/27

  Project: Federal Funding Agencies

• Development of therapeutic mRNA vaccine

  6/28/17 → 6/28/27

  Project: Non Profit

• Training in Neural Control of organ Degeneration and Regeneration (NeuralCODR)

  Horner, P. J.

  7/1/22 → 6/30/27

  Project: Federal Funding Agencies

• A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL, ACTIVE-CONTROLLED STUDY OF TRASTUZUMAB DERUXTECAN (T-DXd) VERSUS TRASTUZUMAB EMTANSINE (T-DM1) IN SUBJECTS WITH HIGH-RISK HER2-POSITIVE PRIMARY BREAST CANCER WHO HAVE RESIDUAL INVASIVE DISEASE IN BREAST OR

  7/6/21 → 7/5/31

  Project: Non Profit

• Multicenter Screening Trial of Safety and Efficacy of Lithium Carbonate in ALS (MDA 105838)

  Greene, E. P.

  California Pacific Medical Ctr Res Inst

  3/1/08 → 7/17/35

  Project: Non Profit

• The VICTORIA Multi-Center Clincial Registery: Visual Interpretation of Completeness and Technical Operative Results using Intra-operative Arteriography in Coronary Artery Bypass Surgery

  East Carolina University

  10/20/08 → 3/6/36

  Project: Non Profit

• Treatment of Preserved Cardiac function heart failure with an Aldosterone an Tagonist (TOPCAT)

  Kurrelmeyer, K. M.

  New England Research Institutes Inc

  3/27/09 → 8/11/36

  Project: Non Profit

• A Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D in premenopausal Women at High Risk for Breast Cancer, Phase IIB

  Chang, J. C. & Singh, M.

  University of Michigan

  6/29/12 → 3/22/37

  Project: Federal Funding Agencies

• Gaining Efficacy Long Term:Hydrosoft and Emerging New Embolic Coil (Gel-the-nec)

  Mayo Clinic

  1/18/10 → 6/4/37

  Project: Non Profit

• Clinical Evaluation of Therapy Cool Path Duo Cardiac Ablation System For the Treatment of Typical Atrial Flutter (Duo FLAIR) Study

  Valderrábano, M.

  St. Jude Medical

  2/8/10 → 6/25/37

  Project: Non Profit

• Prospective multi-center randomized double-blind trial to assess the effectiveness and safety of 12 vs 30 months of dual antiplatelet therapy (DAPT) in subjects undergoing percutaneous coronary intervention (PCI) with either drug-eluting (DES) or bar

  Kleiman, N.

  Harvard Clinical Research Institute

  6/30/10 → 11/14/37

  Project: Non Profit

• TrialNet Natural History Study of the Development of Type 1 Diabetes

  University of South Florida

  9/13/10 → 1/28/38

  Project: Federal Funding Agencies

• Escalating Clopidogrel by Involving a Genetic Strategy (ELEVATE-TIMI 56)

  Kleiman, N.

  Brigham and Women's Hospital

  11/10/10 → 3/27/38

  Project: Non Profit

• Phase IIa Double-Blind, Placebo-Controlled Study to Evaluate the Safety ofOral Fingolimod in Patients with ALS

  Greene, E. P., Appel, S. H. & Lai, E. C.

  Massachusetts General Hospital

  5/13/13 → 5/12/38

  Project: Non Profit

• CAN DIET AND PHYSICAL ACTIVITY MODULATE OVARIAN, FALLOPIAN TUBE AND PRIMARY PERITONEAL CANCER PROGRESSION-FREE SURVIVAL?

  Kamat, A. A., Kaplan, A. L. & Singh, M.

  Gynecologic Oncology Group

  5/14/13 → 5/13/38

  Project: Non Profit

• A Phase II/III Trial of Neoadjuvant FOLFOX w/ Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection w/ Total Mesorectal Excisio

  Bernicker, E. H., Darcourt, J. & Singh, M.

  University of Michigan

  6/11/13 → 6/10/38

  Project: Non Profit

• A PHASE III TRIAL EVALUATING THE ADDITION OF TRASTUZUMAB TO TRIMODALITY TREATMENT OF HER2-OVEREXPRESSING ESOPHAGEAL ADENOCARCINOMA

  Butler, E. B., Kim, M. P. & Teh, B. S.

  University of Michigan

  7/24/13 → 7/23/38

  Project: Non Profit

• EUCLID - Examining Use of tiCagreLor In paD

  Duke University

  8/12/13 → 8/11/38

  Project: Non Profit

• EUCLID - Examining Use of tiCagreLor In paD

  Shah, A. R.

  Duke University

  8/12/13 → 8/11/38

  Project: Non Profit

• PHASE III RANDOMIZED STUDY OF SORAFENIB PLUS DOXORUBICIN VERSUS SORAFENIB IN PATIENTS WITH ADVANCED HEPATOCELLULAR CARCINOMA (HCC)

  Bernicker, E. H., Darcourt, J. & Singh, M.

  University of Michigan

  8/13/13 → 8/12/38

  Project: Non Profit

• GUP09-145(Bionomics);

  Preti, H. A. & Singh, M.

  Hoosier Oncology Group

  7/1/11 → 11/15/38

  Project: Non Profit

• RTOG-0834; RTOG-0913; RTOG-0929

  Radiation Therapy Oncology Group

  8/10/11 → 12/25/38

  Project: Federal Funding Agencies