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• A Novel Organoid Platform to Modulate Human Neural Networks Integrated with Glioblastoma Stem Cells

  Krencik, R. C. & Rostomily, R. C.

  8/31/20 → 8/30/23

  Project: State

• Leveraging glioma stem cell electrophysiology for therapy

  Rostomily, R. C.

  8/31/21 → 8/30/23

  Project: State

• Role of ATRA in Overcoming Myeloma Resistance to Proteasome Inhibitors

  Yi, Q. & Wang, Q.

  8/31/21 → 8/30/23

  Project: State

• Rational Combination Therapy for Aggressive Double-Hit Lymphoma

  Li, Y.

  8/31/20 → 8/30/23

  Project: State

• Translational and Computational Analysis of Dialysis Fistula Maturation Failure

  Casarin, S.

  9/1/20 → 8/31/23

  Project: Federal Funding Agencies

• Cytokine release in SARS CO-V2 viral illness and Trends of inflammasome expression in Acute Respiratory Distress Syndrome manifestations and Management

  Gotur, D. B. & Chang, J. C.

  9/15/20 → 9/14/23

  Project: Non Profit

• NY-ESO-1-specific TCR-Engineered T cell Immunotherapy for Triple Negative Breast Cancer

  Chang, J. C.

  9/30/16 → 9/29/23

  Project: Federal Funding Agencies

• Potentiation of Multi-peptide Lung Cancer Vaccines with Immune Checkpoint Antagonist CA-170

  You, M. & Yi, Q.

  5/24/21 → 11/23/23

  Project: Federal Funding Agencies

• Platelets promote growth of ovarian cancer

  Wong, S. T.

  12/1/18 → 11/30/23

  Project: Federal Funding Agencies

• Effects of Thyroid Hormone Metabolite Treatment for Postmenopausal Heart Repair

  Filgueira, C. S., Bhimaraj, A. & Youker, K. A.

  12/1/21 → 11/30/23

  Project: Federal Funding Agencies

• Mechanism of Intratumoral Transport of Particulate Drugs

  Chen, S.

  6/15/18 → 11/30/23

  Project: Federal Funding Agencies

• Atheroprotection via Reduced Plasma High Density Lipoprotein-Free Cholesterol Bioavailability

  Pownall, H. J., Rosales, C. & Gillard, B. K.

  12/1/19 → 11/30/23

  Project: Federal Funding Agencies

• A Spectroscopic Approach to Overcome the Barriers of Early Familial Hypercholesterolemia Diagnosis

  Filgueira, C. S.

  1/1/22 → 12/31/23

  Project: Federal Funding Agencies

• Regulation of Type I Immunity in diet induced obesity

  Lewis, D. E.

  1/27/20 → 12/31/23

  Project: Federal Funding Agencies

• Genetic mechanism of conserved ancestral haplotype in SCA10

  Ashizawa, T.

  2/1/19 → 12/31/23

  Project: Federal Funding Agencies

• Human Astrocyte-Based Nanovesicles to Target Neuroinflammation in Alzheimer?s Disease

  Krencik, R. C.

  2/15/22 → 1/31/24

  Project: Federal Funding Agencies

• Nanotechnology-based targeting of breast cancer liver metastases

  Godin, B., Chen, S., Niravath, P. A., Rosato, R. R. & Xu, S.

  3/1/21 → 2/29/24

  Project: Federal Funding Agencies

• Photoacoustic Imaging to Guide Catheter Ablation of Cardiac Arrhythmias

  Mathuria, N.

  4/18/22 → 3/31/24

  Project: Federal Funding Agencies

• Targeting ER stress response in B-cell chronic lymphocytic leukemia

  Hu, A., Pingali, S. R. & Tang, C. A.

  4/1/21 → 3/31/24

  Project: Federal Funding Agencies

• Reversal of Heart Failure: Role of Vascular Recovery

  Cooke, J. P. & Youker, K. A.

  7/15/20 → 3/31/24

  Project: Federal Funding Agencies

• Multi-arm Optimization of Stroke Thrombolysis (MOST): a blinded, randomized controlled adaptive, multi-arm, adjunctive-thrombolysis efficacy trial in ischemic stroke.

  6/1/18 → 4/30/24

  Project: Federal Funding Agencies

• Multi-arm Optimization of Stroke Thrombolysis (MOST): a blinded, randomized controlled adaptive, multi-arm, adjunctive-thrombolysis efficacy trial in ischemic stroke.

  Misra, V.

  6/1/18 → 4/30/24

  Project: Federal Funding Agencies

• Novel Therapeutic Strategies to Co-Target AR+ and AR-/lo Prostate Cancer Cells

  6/1/19 → 5/31/24

  Project: Federal Funding Agencies

• The immunosuppressive function of secretory IgM in tumor-bearing mice

  Tang, C. A. & Yin, Z.

  6/1/21 → 5/31/24

  Project: Federal Funding Agencies

• Long non-coding RNA mediated chromatin remodeling in angiogenesis

  Cooke, J. P.

  7/1/19 → 6/30/24

  Project: Federal Funding Agencies

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  Pascual, M. B., Faridar, A. & Masdeu, J. C.

  9/15/19 → 6/30/24

  Project: Non Profit

• Neuromodulation and the Neuroimmune Axis of Repair

  Horner, P. J. & Weng, Y.

  7/31/21 → 7/30/24

  Project: Non Profit

• Role of tumor microenvironment-derived cholesterol in CD8+ T-cell exhaustion

  Yi, Q.

  8/1/19 → 7/31/24

  Project: Federal Funding Agencies

• Anatomical Modeling to Improve the Precision of Image Guided Liver Ablation

  Ensor, Jr., J. E. & Ensor, Jr., J. E.

  9/1/19 → 8/31/24

  Project: Federal Funding Agencies

• Chemoprevention of lung cancer by targeting lonidamine to mitochondria

  You, M., Wang, Y., Xiong, D. & Zhang, Q.

  9/1/21 → 8/31/24

  Project: Federal Funding Agencies

• The University of Texas M.D. Anderson Cancer Center SPORE in Hepatocellular Carcinoma

  Cristini, V.

  9/1/20 → 8/31/24

  Project: Federal Funding Agencies

• Rehabilitation and Research Training Center on Health and Function for People with Physical Disabilities focused on Neurogenic Lower Urinary Tract Dysfunction

  Khavari, R.

  9/30/19 → 9/29/24

  Project: Federal Funding Agencies

• Molecular mechanism of streptococcal adaptation to host nutritional defenses

  Kumaraswami, M. & Olsen, R. J.

  2/25/20 → 1/31/25

  Project: Federal Funding Agencies

• Bioenergetic potentiation in Alzheimer's Disease as a therapeutic strategy

  Blanco, E.

  2/1/22 → 1/31/25

  Project: Non Profit

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Wong, S. T., Zhao, H. & Sheng, J.

  8/1/20 → 1/31/25

  Project: Federal Funding Agencies

• Biophysical roles of pre-metastatic niche evolution on transport of circulating tumor cells

  Kojic, M., Liu, X. & Qin, L.

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Wong, S. T., Zhao, H., Rostomily, R. C. & Sheng, J.

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• A Phase III Randomized, Placebo-Controlled Study of Pembrolizumab (MK-3475, NSC #776864)) in addition to Paclitaxel and Carboplatin for Measurable Stage III or IVA, Stage IVB or Recurrent Endometrial Cancer

  Kamat, A. A., Darcourt, J., Singh, M., Suri, A. & Zaid, T.

  3/1/19 → 2/28/25

  Project: Non Profit

• Exercise Intervention for Strong and Fit Pediatric Fontan Patients (StrongFitFontan)

  Cooke, J. P.

  3/10/20 → 2/28/25

  Project: Federal Funding Agencies

• NRG-BR004: A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Geyer, C. E., Chang, J. C., Darcourt, J. & Niravath, P. A.

  3/12/19 → 2/28/25

  Project: Non Profit

• RE-ENERGIZE FONTAN - RandomizEd Exercise INtERvention desiGned to MaximIZE Fitness in Pediatric FONTAN patients

  Cooke, J. P.

  3/26/21 → 2/28/25

  Project: Federal Funding Agencies

• Defining the altered FUS-PARP-1-DNA Ligase III axis and its implications to nuclear and mitochondrial genome damage response in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

  Hegde, M., Hamilton, D. J., Horner, P. J., Mitra, J. & Wang, H.

  4/15/20 → 3/31/25

  Project: Federal Funding Agencies

• Novel carbon nanozyme mechanisms for traumatic brain injury therapy

  Hegde, M.

  4/1/20 → 3/31/25

  Project: Federal Funding Agencies

• Age-related TDP-43 neuropathology: using disease-driving mechanisms to guide classification

  Cykowski, M. D.

  9/15/20 → 3/31/25

  Project: Federal Funding Agencies

• Systems-wide analysis of oxidative stress-responsive m6A epitranscriptome

  Weng, Y. & Krencik, R. C.

  6/15/20 → 3/31/25

  Project: Federal Funding Agencies

• Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered Vein-Chip.

  Cooke, J. P.

  5/1/21 → 4/30/25

  Project: Federal Funding Agencies

• Prospective Sudden Cardiac Death Risk Stratification Using Cardiac MRI and Echocardiography Machine Learning in Mitral Valve Prolapse.

  Shah, D. J.

  5/26/20 → 4/30/25

  Project: Federal Funding Agencies

• Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease

  Masdeu, J. C.

  9/30/20 → 4/30/25

  Project: Federal Funding Agencies

• Convergent AI for Precise Breast Cancer Risk Assessment

  Wong, S. T., Chang, J. C. & Ensor, Jr., J. E.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Influence of pre-analytical factors in glioblastoma MGMT promoter methylation biomarker assay

  Rostomily, R. C., Mitra, S. & Powell, S. Z.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies