Find Research Projects

Search results

• Active

  Elucidating the role(s) of cytoplasmic capping in the response to oxidative stress in vascular endothelial cells

  Kiss, D. L.

  7/1/20 → 6/30/23

  Project: Non Profit

• Transcriptional Control of Gliogenesis in the CNS

  Cykowski, M. D.

  7/1/20 → 6/30/21

  Project: Federal Funding Agencies

• Targeting novel checkpoint regulator to control viral myocarditis

  Xing, J., Cooke, J. P., Li, X. C. & Zhang, Z.

  7/1/20 → 6/30/23

  Project: Non Profit

• Synchrony: Holistic Program for Veterans

  Madan, A. & Fowler, C.

  7/1/20 → 6/30/21

  Project: Non Profit

• AOCT - I-MAB Phase 1b2 study of TJ003234 in Subjects with Severe COVID 19

  Gotur, D. B., Hsu, S. H., Moran, D., Perez, K. K. & Sanchez Leon, R.

  6/26/20 → …

  Project: Clinical Trial

• NeuroRX - COVID-19 - RLF-100 ALIARDS

  Youssef, J. G., Al-Saadi, M. A., Grimes, K. A. & Zahiruddin, F.

  6/26/20 → …

  Project: Clinical Trial

• Phase 3 Multicenter, Double-Blind, randomized, placebo-controlled trail of Infigratinib for the Adjuvant Treatment of Subjects with Invasive Urothelial Carcinoma with Susceptible FGFR3 Genetic Alterations (PROOF 302)

  Satkunasivam, R., Darcourt, J., Singh, M. & Zhang, J.

  6/26/20 → …

  Project: Clinical Trial

• SH-PROTECTED TAVR

  Kleiman, N., Goel, S., Reardon, M. J. & Volpi, J. J.

  6/24/20 → …

  Project: Clinical Trial

• Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer (NRG-GY020)

  Farach, A. M., Alaniz, A., Butler, E. B., Darcourt, J., Haque, W. M., Morgan, P. B., Shadle, K. M., Shkedy, C., Singh, M., Suri, A. & Zaid, T.

  6/22/20 → …

  Project: Clinical Trial

• AOCT-FUJIFILMPhase 2 Proof-of-Concept Study of the Use of Favipiravir v. Standard of Care in Hospitalized Subjects with COVID-19

  Ashraf, M., Jaijakul, S. & Perez, K. K.

  6/19/20 → …

  Project: Clinical Trial

• Gingival Bacteria in AD - GAIN Trial

  Masdeu, J. C., Faridar, A. & Nakawah, M. O.

  6/17/20 → …

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo

  Niravath, P. A., Abdelrahim, M., Arentz, C., Chang, J. C., Darcourt, J., Geyer, C. E., Heyne, K. & Singh, M.

  6/16/20 → …

  Project: Clinical Trial

• CMR for COVID Patients

  Shah, D. J., Graviss, E. A., Malahfji, M., Nasir, K. & Yang, E. Y.

  6/16/20 → …

  Project: Clinical Trial

• Systems-wide analysis of oxidative stress-responsive m6A epitranscriptome

  Weng, Y. & Krencik, R. C.

  6/15/20 → 3/31/25

  Project: Federal Funding Agencies

• HOPE Part 2 - Heron

  Swan, J. T., Caplan, R. E., Gaber, A. O. & Moore, L. W.

  6/5/20 → …

  Project: Clinical Trial

• Influence of pre-analytical factors in glioblastoma MGMT promoter methylation biomarker assay

  Rostomily, R. C., Mitra, S. & Powell, S. Z.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Convergent AI for Precise Breast Cancer Risk Assessment

  Wong, S. T., Chang, J. C. & Ensor, Jr., J. E.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Novel Therapeutic Strategies to Co-Target Undifferentiated Prostate Cancer (PCa) Stem Cells and Bulk PCa Cells

  Shen, H.

  6/1/20 → 5/31/21

  Project: Federal Funding Agencies

• ALLFTD

  Pascual, B., Faridar, A. & Masdeu, J. C.

  6/1/20 → …

  Project: Clinical Trial

• AOCT-ALXN-Efficacy and Safety Study of IV Ravulizumab in Patients with COVID-19 Severe Pneumonia

  Khoshnevis, M. R., Al-Saadi, M. A., Gotur, D. B., Hsu, S. H., Moran, D., Rice, L. & Sanchez Leon, R.

  5/27/20 → …

  Project: Clinical Trial

• A Phase III, Multicenter, Open-Label, Extension Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow® Device plus Standard of Care in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post Single or Double Lung Transplantation (BT-L-CsA-303-FU (BOSTON-3))

  Goodarzi, A., Yau, S. W. & Youssef, J. G.

  5/27/20 → …

  Project: Clinical Trial

• Phase III Trial of Docetaxel vs. Docetaxel and Radium-223 for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

  Darcourt, J., Heyne, K., Singh, M. & Zhang, J.

  5/27/20 → …

  Project: Clinical Trial

• Prospective Sudden Cardiac Death Risk Stratification Using Cardiac MRI and Echocardiography Machine Learning in Mitral Valve Prolapse.

  Shah, D. J.

  5/26/20 → 4/30/25

  Project: Federal Funding Agencies

• SH-AltaValve.

  Faza, N., Goel, S., Kleiman, N., Lawrie, G. M., Little, S. H., Mahmarian, J. J. & Reardon, M. J.

  5/19/20 → …

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab With Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Geyer, C. E., Chang, J. C., Darcourt, J. & Niravath, P. A.

  5/19/20 → …

  Project: Clinical Trial

• A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

  Singh, M., Abdelrahim, M., Beinart, G. & Heyne, K.

  5/18/20 → …

  Project: Clinical Trial

• AOCT - AERIN AERWAY For Nasal Airway Obstruction

  Takashima, M.

  5/13/20 → …

  Project: Clinical Trial

• Evaluation of immune responses to CD44-targeted nanovectors for designing a novel anti-tuberculosis host-directed therapy

  Godin, B., Jagannath, C. & Leonard, F.

  5/1/20 → 4/30/21

  Project: Federal Funding Agencies

• iNOINOpulse PULSE-EAP-001_compassionate use for COVID 19

  Youssef, J. G., Sahay, S. & Zahiruddin, F.

  4/28/20 → …

  Project: Clinical Trial

• A Phase 2, Multicenter, Open-label, Safety and Efficacy Study of XERMELO® (Telotristat Ethyl) Plus First-line Chemotherapy in Patients With Locally Advanced, Unresectable, Recurrent or Metastatic Biliary Tract Cancer (BTC)

  Abdelrahim, M., Bernicker, E. H., Chang, J. C., Darcourt, J., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  4/27/20 → …

  Project: Clinical Trial

• A Randomized, Open-Label Extension Study to Investigate the Long-Term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

  Shroff, S., Appel, S. H., Greene, E. P. & Thonhoff, J. R.

  4/23/20 → …

  Project: Clinical Trial

• A PILOT RANDOMIZED CONTROLLED TRIAL OF DE NOVO BELATACEPT-BASED IMMUNOSUPPRESSION IN LUNG TRANSPLANTATION

  Goodarzi, A. & Yau, S. W.

  4/23/20 → …

  Project: Clinical Trial

• Voice Rest Adherence After Phonomicrosurgery

  Yiu, Y.

  4/20/20 → 3/31/23

  Project: Federal Funding Agencies

• Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

  Randhawa, J., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  4/17/20 → …

  Project: Clinical Trial

• DOD - Dehisced-Wound

  Bonville, D. J. & Rupert, P.

  4/16/20 → …

  Project: Clinical Trial

• Defining the altered FUS-PARP-1-DNA Ligase III axis and its implications to nuclear and mitochondrial genome damage response in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

  Hegde, M., Hamilton, D. J., Horner, P. J. & Wang, H.

  4/15/20 → 3/31/25

  Project: Federal Funding Agencies

• SANOFI - TED16414

  Gaber, A. O., Knight, R. J. & Yi, S.

  4/15/20 → …

  Project: Clinical Trial

• Biodegradability and Biocompatiblity of a Shape Memory Polymer Wrap to Improve Saphenous Vein Graft Patency in Peripheral and Coronary Artery Bypass Grafting Surgeries

  Peden, E. K., Cooke, J. P. & Karmonik, C.

  4/15/20 → 10/31/21

  Project: Federal Funding Agencies

• A new conditional TDP¿NLS knock-in mouse model generated using CRISPR/Cas9 technology to study the linkage of TDP-43 pathology to motor and cognitive defects in ALS

  Hegde, M. & Wang, H.

  4/15/20 → 2/28/22

  Project: Federal Funding Agencies

• Phase III Efficacy, Safety, and Tolerability Study of HYQVIA/HyQvia and GAMMAGARD LIQUID/KIOVIG in CIDP

  Greene, E. P., Appel, S. H., Shroff, S. & Thonhoff, J. R.

  4/15/20 → …

  Project: Clinical Trial

• Sample and Data Collection for Houston Methodist Cancer Center Research

  Chang, J. C., Bernicker, E. H., Darcourt, J., Heyne, K., Niravath, P. A. & Singh, M.

  4/9/20 → …

  Project: Clinical Trial

• A Randomized, Open-label, Phase II Study of Canakinumab or Pembrolizumab as Monotherapy or in Combination as Neoadjuvant Therapy in Subjects With Resectable Non-small Cell Lung Cancer (CANOPY-N)

  Bernicker, E. H., Barrios, R., Chan, E. Y., Chang, J. C., Darcourt, J., Heyne, K., Kim, M. P., Niravath, P. A., Singh, M. & Zhang, J.

  4/9/20 → …

  Project: Clinical Trial

• ABBV-8E12 Anti-tau Antibody in AD - Extension Study

  Masdeu, J. C., Faridar, A. & Nakawah, M. O.

  4/9/20 → …

  Project: Clinical Trial

• Intraoperative Analytics and Enhanced Patient Outcomes

  4/5/20 → 4/4/21

  Project: Federal Funding Agencies

• Novel carbon nanozyme mechanisms for traumatic brain injury therapy

  Hegde, M.

  4/1/20 → 3/31/25

  Project: Federal Funding Agencies

• LEAP-012 - MERCK (7902-012, Site No. 0784)

  Ghobrial, R. M., Abdelrahim, M., Gibbs, J. M., Heyne, K., Shetty, A. & Victor, III, D. W.

  3/27/20 → …

  Project: Clinical Trial

• Takeda - TAK-018-2001

  Abraham, B. P. & Glassner, K.

  3/27/20 → …

  Project: Clinical Trial

• AOCT - Convalescent Plasma - COVID-19

  Salazar, E., Ashraf, M., Castillo, B., Chen, J., Leveque, C., Masud, F. N. & Perez, K. K.

  3/26/20 → …

  Project: Clinical Trial

• A Pilot Randomized Controlled Trial of De Novo Belatacept-Based Immunosuppression in Lung Transplantation

  3/26/20 → 3/25/45

  Project: Non Profit

• AOCT - COVID-19 Plasma Donation

  Salazar, E., Castillo, B., Chen, J. & Leveque, C.

  3/26/20 → …

  Project: Clinical Trial