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Elucidating the role(s) of cytoplasmic capping in the response to oxidative stress in vascular endothelial cells
7/1/20 → 6/30/23
Project: Non Profit
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Targeting novel checkpoint regulator to control viral myocarditis
Xing, J., Cooke, J. P., Li, X. C. & Zhang, Z.
7/1/20 → 6/30/23
Project: Non Profit
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AOCT - I-MAB Phase 1b2 study of TJ003234 in Subjects with Severe COVID 19
Gotur, D. B., Hsu, S. H., Moran, D., Perez, K. K. & Sanchez Leon, R.
6/26/20 → …
Project: Clinical Trial
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NeuroRX - COVID-19 - RLF-100 ALIARDS
Youssef, J. G., Al-Saadi, M. A., Grimes, K. A. & Zahiruddin, F.
6/26/20 → …
Project: Clinical Trial
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Phase 3 Multicenter, Double-Blind, randomized, placebo-controlled trail of Infigratinib for the Adjuvant Treatment of Subjects with Invasive Urothelial Carcinoma with Susceptible FGFR3 Genetic Alterations (PROOF 302)
Satkunasivam, R., Darcourt, J., Singh, M. & Zhang, J.
6/26/20 → …
Project: Clinical Trial
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SH-PROTECTED TAVR
Kleiman, N., Goel, S., Reardon, M. J. & Volpi, J. J.
6/24/20 → …
Project: Clinical Trial
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Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer (NRG-GY020)
Farach, A. M., Alaniz, A., Butler, E. B., Darcourt, J., Haque, W. M., Morgan, P. B., Shadle, K. M., Shkedy, C., Singh, M., Suri, A. & Zaid, T.
6/22/20 → …
Project: Clinical Trial
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Gingival Bacteria in AD - GAIN Trial
Masdeu, J. C., Faridar, A. & Nakawah, M. O.
6/17/20 → …
Project: Clinical Trial
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A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo
Niravath, P. A., Abdelrahim, M., Arentz, C., Chang, J. C., Darcourt, J., Geyer, C. E., Heyne, K. & Singh, M.
6/16/20 → …
Project: Clinical Trial
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CMR for COVID Patients
Shah, D. J., Graviss, E. A., Malahfji, M., Nasir, K. & Yang, E. Y.
6/16/20 → …
Project: Clinical Trial
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Systems-wide analysis of oxidative stress-responsive m6A epitranscriptome
6/15/20 → 3/31/25
Project: Federal Funding Agencies
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HOPE Part 2 - Heron
Swan, J. T., Caplan, R. E., Gaber, A. O. & Moore, L. W.
6/5/20 → …
Project: Clinical Trial
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Influence of pre-analytical factors in glioblastoma MGMT promoter methylation biomarker assay
Rostomily, R. C., Mitra, S. & Powell, S. Z.
6/1/20 → 5/31/25
Project: Federal Funding Agencies
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Convergent AI for Precise Breast Cancer Risk Assessment
Wong, S. T., Chang, J. C. & Ensor, Jr., J. E.
6/1/20 → 5/31/25
Project: Federal Funding Agencies
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Novel Therapeutic Strategies to Co-Target Undifferentiated Prostate Cancer (PCa) Stem Cells and Bulk PCa Cells
6/1/20 → 5/31/21
Project: Federal Funding Agencies
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AOCT-ALXN-Efficacy and Safety Study of IV Ravulizumab in Patients with COVID-19 Severe Pneumonia
Khoshnevis, M. R., Al-Saadi, M. A., Gotur, D. B., Hsu, S. H., Moran, D., Rice, L. & Sanchez Leon, R.
5/27/20 → …
Project: Clinical Trial
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A Phase III, Multicenter, Open-Label, Extension Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow® Device plus Standard of Care in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post Single or Double Lung Transplantation (BT-L-CsA-303-FU (BOSTON-3))
Goodarzi, A., Yau, S. W. & Youssef, J. G.
5/27/20 → …
Project: Clinical Trial
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Phase III Trial of Docetaxel vs. Docetaxel and Radium-223 for Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Darcourt, J., Heyne, K., Singh, M. & Zhang, J.
5/27/20 → …
Project: Clinical Trial
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Prospective Sudden Cardiac Death Risk Stratification Using Cardiac MRI and Echocardiography Machine Learning in Mitral Valve Prolapse.
5/26/20 → 4/30/25
Project: Federal Funding Agencies
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SH-AltaValve.
Faza, N., Goel, S., Kleiman, N., Lawrie, G. M., Little, S. H., Mahmarian, J. J. & Reardon, M. J.
5/19/20 → …
Project: Clinical Trial
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A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy
Singh, M., Abdelrahim, M., Beinart, G. & Heyne, K.
5/18/20 → …
Project: Clinical Trial
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Evaluation of immune responses to CD44-targeted nanovectors for designing a novel anti-tuberculosis host-directed therapy
Godin, B., Jagannath, C. & Leonard, F.
5/1/20 → 4/30/21
Project: Federal Funding Agencies
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iNOINOpulse PULSE-EAP-001_compassionate use for COVID 19
Youssef, J. G., Sahay, S. & Zahiruddin, F.
4/28/20 → …
Project: Clinical Trial
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A Phase 2, Multicenter, Open-label, Safety and Efficacy Study of XERMELO® (Telotristat Ethyl) Plus First-line Chemotherapy in Patients With Locally Advanced, Unresectable, Recurrent or Metastatic Biliary Tract Cancer (BTC)
Abdelrahim, M., Bernicker, E. H., Chang, J. C., Darcourt, J., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.
4/27/20 → …
Project: Clinical Trial
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A PILOT RANDOMIZED CONTROLLED TRIAL OF DE NOVO BELATACEPT-BASED IMMUNOSUPPRESSION IN LUNG TRANSPLANTATION
4/23/20 → …
Project: Clinical Trial
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Biodegradability and Biocompatiblity of a Shape Memory Polymer Wrap to Improve Saphenous Vein Graft Patency in Peripheral and Coronary Artery Bypass Grafting Surgeries
Peden, E. K., Cooke, J. P. & Karmonik, C.
4/15/20 → 10/31/21
Project: Federal Funding Agencies
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A new conditional TDP¿NLS knock-in mouse model generated using CRISPR/Cas9 technology to study the linkage of TDP-43 pathology to motor and cognitive defects in ALS
4/15/20 → 2/28/22
Project: Federal Funding Agencies
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Phase III Efficacy, Safety, and Tolerability Study of HYQVIA/HyQvia and GAMMAGARD LIQUID/KIOVIG in CIDP
Greene, E. P., Appel, S. H., Shroff, S. & Thonhoff, J. R.
4/15/20 → …
Project: Clinical Trial
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Sample and Data Collection for Houston Methodist Cancer Center Research
Chang, J. C., Bernicker, E. H., Darcourt, J., Heyne, K., Niravath, P. A. & Singh, M.
4/9/20 → …
Project: Clinical Trial
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A Randomized, Open-label, Phase II Study of Canakinumab or Pembrolizumab as Monotherapy or in Combination as Neoadjuvant Therapy in Subjects With Resectable Non-small Cell Lung Cancer (CANOPY-N)
Bernicker, E. H., Barrios, R., Chan, E. Y., Chang, J. C., Darcourt, J., Heyne, K., Kim, M. P., Niravath, P. A., Singh, M. & Zhang, J.
4/9/20 → …
Project: Clinical Trial
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ABBV-8E12 Anti-tau Antibody in AD - Extension Study
Masdeu, J. C., Faridar, A. & Nakawah, M. O.
4/9/20 → …
Project: Clinical Trial
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Intraoperative Analytics and Enhanced Patient Outcomes
4/5/20 → 4/4/21
Project: Federal Funding Agencies
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Novel carbon nanozyme mechanisms for traumatic brain injury therapy
4/1/20 → 3/31/25
Project: Federal Funding Agencies
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LEAP-012 - MERCK (7902-012, Site No. 0784)
Ghobrial, R. M., Abdelrahim, M., Gibbs, J. M., Heyne, K., Shetty, A. & Victor, III, D. W.
3/27/20 → …
Project: Clinical Trial
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AOCT - Convalescent Plasma - COVID-19
Salazar, E., Ashraf, M., Castillo, B., Chen, J., Leveque, C., Masud, F. N. & Perez, K. K.
3/26/20 → …
Project: Clinical Trial
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A Pilot Randomized Controlled Trial of De Novo Belatacept-Based Immunosuppression in Lung Transplantation
3/26/20 → 3/25/45
Project: Non Profit
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AOCT - COVID-19 Plasma Donation
Salazar, E., Castillo, B., Chen, J. & Leveque, C.
3/26/20 → …
Project: Clinical Trial