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• An Open-Label Randomized Active-Controlled Phase II Clinical Study to Assess the Efficacy and Safety of Afuresertib Plus Paclitaxel Versus Paclitaxel in Patients with Platinum-ResistantOvarian Cancer

  Kamat, A. A., Alaniz, A., Darcourt, J., Singh, M., Suri, A. & Zaid, T.

  3/15/21 → 3/14/46

  Project: Non Profit

• A novel 3D cell culture human uterine contractility assay for high-throughput screening and mechanistic evaluation of tocolytic substances

  Godin, B.

  Nano3D Biosciences Inc

  9/22/14 → 8/31/16

  Project: Federal Funding Agencies

• A Novel eFace System to Prevent the Risks of Facial Distortion after CMF Surgery

  Natl Inst of Dental and Craniofacial Res

  4/1/16 → 3/31/19

  Project: Federal Funding Agencies

• A Novel eFace System to Prevent the Risks of Facial Distortion after CMF Surgery

  Gateno, J.

  Natl Inst of Dental and Craniofacial Res

  5/1/13 → 3/31/16

  Project: Federal Funding Agencies

• A Novel Ex Vivo Three Dimensional Model for the Isolation and Identification of Circulating Tumor Cells

  Kim, M. P.

  American Asso for Thoracic Surgery

  7/1/13 → 6/30/19

  Project: Non Profit

• A NOVEL HISTONE MODIFICATION MEDIATES DNA ACCESSIBILITY: ROLE OF INOS

  Cooke, J. P.

  1/1/20 → 12/31/21

  Project: Non Profit

• A Novel Imaging Analysis Platform for Patients with Craniomaxillofacial Deformities

  Gateno, J.

  Natl Inst of Dental and Craniofacial Res

  2/1/16 → 1/31/23

  Project: Federal Funding Agencies

• A novel imaging informatics platform for craniomaxillofacial surgery

  Gateno, J.

  Natl Inst of Dental and Craniofacial Res

  9/7/11 → 8/31/15

  Project: Federal Funding Agencies

• A Novel M2 Lipogenic Macrophage Associated with Fracture Callus are Altered in Type 2 Diabetes

  Davis, B.

  6/1/21 → 5/31/23

  Project: Federal Funding Agencies

• A Novel Multi-Antigen Vaccine (TNBCvax) to Prevent Triple Negative Breast Cancer

  You, M.

  9/16/21 → 3/15/23

  Project: Federal Funding Agencies

• A novel nanochannel system for sustained delivery of Tenofovir Alafenamide Fumarate and Emtricitabine for HIV pre-exposure prophylaxis

  Grattoni, A.

  National Institutes of Health

  6/20/16 → 5/31/22

  Project: Federal Funding Agencies

• A Novel Non-Invasive Approach for Regaining Self-Assisted Standing after Spinal Cord Injury: Combining Transcutaneous Spinal Stimulation and Functional Electrical Stimulation

  Sayenko, D.

  7/1/20 → 7/31/23

  Project: Non Profit

• A Novel Organoid Platform to Modulate Human Neural Networks Integrated with Glioblastoma Stem Cells

  Krencik, R. C. & Rostomily, R. C.

  8/31/20 → 8/30/23

  Project: State

• A Novel Pathway involving ATM PP1 and I-2

  8/16/10 → 10/31/10

  Project: Federal Funding Agencies

• A Novel Pathway Involving ATM PP1 and I-2

  Mitra, S.

  Natl Inst of Environmental Health Sci

  1/28/10 → 3/31/14

  Project: Federal Funding Agencies

• A Novel Role for MAGI1 in regulating non-canonical LATS signaling and atherosclerotic plaque formation

  Le, N.

  1/1/18 → 2/28/23

  Project: Federal Funding Agencies

• A novel role for polycomb group proteins in androgen signaling and prostate cancer.

  Cao, Q.

  Prostate Cancer Foundation

  5/20/13 → 6/30/18

  Project: Non Profit

• A novel T-cell subset able to kill relapsed cancers

  Yi, Q.

  7/1/16 → 6/30/22

  Project: Federal Funding Agencies

• A novel tool in high- dimensional single-cell space to predict neurotoxicity of CAR T cell therapies

  Lu, Y.

  8/1/21 → 7/31/26

  Project: Federal Funding Agencies

• A novel treatment strategy to target the underlying causes of both the wet and dry forms of AMD

  Fang, L.

  7/1/18 → 6/30/21

  Project: Non Profit

• Antigen specificity, suppressive mechanism & regulation of CD4+ regulatory T cell

  Wang, R.

  National Cancer Institute

  2/17/12 → 7/31/13

  Project: Federal Funding Agencies

• An ultra-sensitive nanomagnetic sensor for the early detection of anaplactic large cell lymphoma

  Zu, Y.

  University of Houston

  5/1/15 → 2/28/19

  Project: State

• AOCT - Amulet IDE Study

  Valderrábano, M.

  Project: Clinical Trial

• AOCT-A Phase 2b, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study with Open-Label Extension to Evaluate the Safety and Efficacy of ST266 Eye Drops in the Treatment of Persistent Corneal Epithelial Defects

  Pandit, R. & Queen, J. H.

  Project: Clinical Trial

• AOCT - Athena Study

  Friedman, J. D., Albright, S. & Ellsworth, IV, W. A.

  Project: Clinical Trial

• AOCT - Convalescent Plasma - COVID-19

  Castillo, B., Chen, J. & Leveque, C.

  Project: Clinical Trial

• AOCT - COVID-19 Plasma Donation

  Castillo, B., Chen, J. & Leveque, C.

  3/26/20 → …

  Project: Clinical Trial

• AOCT - Intuitive da Vinci SP in Colorectal Surgical Procedures

  6/28/21 → …

  Project: Clinical Trial

• AOCT - Phase3_MK4482-013_COVID-19

  Moran, D., Gotur, D. B. & Zahiruddin, F.

  Project: Clinical Trial

• AOCT - Sugar Land - AEGIS-II

  Kleiman, N.

  11/1/19 → …

  Project: Clinical Trial

• AOCT - Zephyr Valve Registry ZEVR

  Kopas, L.

  2/3/20 → …

  Project: Clinical Trial

• APEX1 is a critical cytosolic molecule to sense self DNAs in autoimmune diseases

  Zhang, Z.

  Baylor Research Institute

  5/1/14 → 4/30/16

  Project: Federal Funding Agencies

• A Phase 0, Investigator Initiated Study, Evaluating the Impact of Omega 3 Free Fatty Acid Supplementation on Aromatase in Obese Subjects (CTMS# 15-2100)

  Niravath, P. A., Chang, J. C. & Darcourt, J.

  12/1/16 → 11/30/18

  Project: Federal Funding Agencies

• A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

  Singh, M., Abdelrahim, M., Beinart, G. & Heyne, K.

  5/18/20 → …

  Project: Clinical Trial

• A Phase 1b Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Bemarituzumab in Combination with Other Anti-Cancer Therapies in Subjects with Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer with FGFR2b Overexpression (FORTITUDE-103)

  Abdelrahim, M., Bernicker, E. H., Heyne, K., Singh, M. & Zhang, J.

  Project: Clinical Trial

• A PHASE 2, DOUBLE-BLIND, RANDOMIZED, PLACEBOCONTROLLED, DOSE-RESPONSE STUDY OF SAGE-324 FOR THE TREATMENT OF ESSENTIAL TREMOR

  Waln, O. & Billnitzer, A.

  Project: Clinical Trial

• A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants With Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

  Adrogue, H. E.

  Project: Clinical Trial

• A Phase 2, Randomized, Double-Blind, Double-Dummy, Placebo-Controlled Study Evaluating the Safety and Efficacy of Semaglutide, and the Fixed-Dose Combination of Cilofexor and Firsocostat, Alone and in Combination, in Subjects With Compensated Cirrhosis (F4) Due to Nonalcoholic Steatohepatitis (NASH)

  Victor, III, D. W. & Kodali, S.

  10/11/22 → …

  Project: Clinical Trial

• A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Clinical Trial to Evaluate the Tolerability, Safety, and Efficacy of PRAX-944 in the Treatment of Adults with Essential Tremor

  Waln, O. & Billnitzer, A.

  9/28/22 → …

  Project: Clinical Trial

• A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of K0706 in Subjects With Early Parkinson's Disease

  Ondo, W. G. & Waln, O.

  10/22/19 → …

  Project: Clinical Trial

• A Phase 2a, Double-Blind, Randomized, Active Controlled, Parallel Group Study Evaluating the Efficacy, Safety, and Tolerability of Bezafibrate Administered in Combination with Obeticholic Acid in Subjects with Primary Biliary Cholangitis

  Victor, III, D. W. & Kodali, S.

  10/14/22 → …

  Project: Clinical Trial

• A Phase 2b, 12-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study of the Safety and Efficacy of JZP385 in the Treatment of Adults with Moderate to Severe Essential Tremor

  Waln, O. & Ondo, W. G.

  8/8/22 → …

  Project: Clinical Trial

• A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension (ELEVATE 2)

  Sahay, S. & Safdar, Z.

  7/21/22 → …

  Project: Clinical Trial

• A PHASE 2 STUDY OF FUTIBATINIB IN PATIENTS WITH SPECIFIC FGFR ABERRATIONS

  Abdelrahim, M., Heyne, K. & Singh, M.

  Project: Clinical Trial

• A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, 27-Week Trial to Evaluate the Efficacy, Safety, and Tolerability of Two Fixed Doses of Tavapadon in Early Parkinson's Disease (TEMPO-1 TRIAL)

  Ondo, W. G. & Waln, O.

  8/6/20 → …

  Project: Clinical Trial

• A Phase 3, Multicenter, Randomized, Controlled, Open-Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1)

  Faisal, H., Dhala, A., Masud, F. N., Mobley, C. M. & Moore, L. W.

  2/3/23 → …

  Project: Clinical Trial

• A Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in Participants With High-Risk HER2-Positive Primary Breast Cancer Who Have Residual Invasive Disease in Breast

  Chang, J. C. & Niravath, P. A.

  7/30/21 → …

  Project: Clinical Trial

• A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL, ACTIVE-CONTROLLED STUDY OF TRASTUZUMAB DERUXTECAN (T-DXd) VERSUS TRASTUZUMAB EMTANSINE (T-DM1) IN SUBJECTS WITH HIGH-RISK HER2-POSITIVE PRIMARY BREAST CANCER WHO HAVE RESIDUAL INVASIVE DISEASE IN BREAST OR

  7/6/21 → 7/5/31

  Project: Non Profit

• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Compare the Efficacy and Safety of Sotatercept Versus Placebo When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH_A011-11 (STELLAR)

  Safdar, Z. & Sahay, S.

  7/30/21 → …

  Project: Clinical Trial

• A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-322)

  Shah, S., Ganguly, S., Petkova, J., Pingali, S. R. & Rice, L.

  9/21/22 → …

  Project: Clinical Trial