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• A novel nanochannel system for sustained delivery of Tenofovir Alafenamide Fumarate and Emtricitabine for HIV pre-exposure prophylaxis

  Grattoni, A.

  National Institutes of Health

  6/20/16 → 5/31/22

  Project: Federal Funding Agencies

• A Novel Non-Invasive Approach for Regaining Self-Assisted Standing after Spinal Cord Injury: Combining Transcutaneous Spinal Stimulation and Functional Electrical Stimulation

  Sayenko, D.

  7/1/20 → 6/30/22

  Project: Non Profit

• A Novel Organoid Platform to Modulate Human Neural Networks Integrated with Glioblastoma Stem Cells

  Krencik, R. C. & Rostomily, R. C.

  8/31/20 → 8/30/22

  Project: State

• A Novel Pathway involving ATM PP1 and I-2

  8/16/10 → 10/31/10

  Project: Federal Funding Agencies

• A Novel Pathway Involving ATM PP1 and I-2

  Mitra, S.

  Natl Inst of Environmental Health Sci

  1/28/10 → 3/31/14

  Project: Federal Funding Agencies

• A Novel Role for MAGI1 in regulating non-canonical LATS signaling and atherosclerotic plaque formation

  Le, N.

  1/1/18 → 2/28/23

  Project: Federal Funding Agencies

• A novel role for polycomb group proteins in androgen signaling and prostate cancer.

  Cao, Q.

  Prostate Cancer Foundation

  5/20/13 → 6/30/18

  Project: Non Profit

• A novel T-cell subset able to kill relapsed cancers

  Yi, Q.

  7/1/16 → 6/30/22

  Project: Federal Funding Agencies

• A novel treatment strategy to target the underlying causes of both the wet and dry forms of AMD

  Fang, L.

  7/1/18 → 6/30/21

  Project: Non Profit

• Antigen specificity, suppressive mechanism & regulation of CD4+ regulatory T cell

  Wang, R.

  National Cancer Institute

  2/17/12 → 7/31/13

  Project: Federal Funding Agencies

• An ultra-sensitive nanomagnetic sensor for the early detection of anaplactic large cell lymphoma

  Zu, Y.

  University of Houston

  5/1/15 → 2/28/19

  Project: State

• AOCT - Amulet IDE Study

  Valderrábano, M.

  Project: Clinical Trial

• AOCT-A Phase 2b, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study with Open-Label Extension to Evaluate the Safety and Efficacy of ST266 Eye Drops in the Treatment of Persistent Corneal Epithelial Defects

  Pandit, R. & Queen, J. H.

  4/20/22 → …

  Project: Clinical Trial

• AOCT - Athena Study

  Friedman, J. D., Albright, S. & Ellsworth, IV, W. A.

  Project: Clinical Trial

• AOCT - ATLAS - Knee Study

  McCulloch, P.

  Project: Clinical Trial

• AOCT - Convalescent Plasma - COVID-19

  Castillo, B., Ashraf, M., Chen, J. & Leveque, C.

  Project: Clinical Trial

• AOCT - COVID-19 Plasma Donation

  Castillo, B., Chen, J. & Leveque, C.

  3/26/20 → …

  Project: Clinical Trial

• AOCT - DISRUPT - Exebacase

  Ashraf, M. & Jaijakul, S.

  Project: Clinical Trial

• AOCT - Intuitive da Vinci SP in Colorectal Surgical Procedures

  6/28/21 → …

  Project: Clinical Trial

• AOCT - MOTIVA Implants CLIN-17-008

  Ellsworth, IV, W. A., Gratzon, A. C. & Spiegel, A.

  12/29/21 → …

  Project: Clinical Trial

• AOCT - Phase 23_PF-07321332RITONAVIR_Low-Risk COVID-19_C4671002

  Youssef, J. G., Goodarzi, A., Yau, S. W. & Zahiruddin, F.

  10/21/21 → …

  Project: Clinical Trial

• AOCT - Phase3_MK4482-013_COVID-19

  Moran, D., Gotur, D. B. & Zahiruddin, F.

  9/15/21 → …

  Project: Clinical Trial

• AOCT - Pilot Study to explore toxicity and efficacy of Secukinumab in COVID-19 disease

  Gotur, D. B., Ashraf, M. & Moran, D.

  Project: Clinical Trial

• AOCT - Sugar Land - AEGIS-II

  Kleiman, N.

  11/1/19 → …

  Project: Clinical Trial

• AOCT - Zephyr Valve Registry ZEVR

  Kopas, L.

  2/3/20 → …

  Project: Clinical Trial

• APEX1 is a critical cytosolic molecule to sense self DNAs in autoimmune diseases

  Zhang, Z.

  Baylor Research Institute

  5/1/14 → 4/30/16

  Project: Federal Funding Agencies

• A Phase 0, Investigator Initiated Study, Evaluating the Impact of Omega 3 Free Fatty Acid Supplementation on Aromatase in Obese Subjects (CTMS# 15-2100)

  Niravath, P. A., Chang, J. C. & Darcourt, J.

  12/1/16 → 11/30/18

  Project: Federal Funding Agencies

• A Phase 1a/b Dose-Escalation Study Followed by Expansion Cohorts of NGM120, a GFRAL Antagonist Monoclonal Antibody Blocking GDF15 Signaling, in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

  Singh, M., Abdelrahim, M., Beinart, G. & Heyne, K.

  5/18/20 → …

  Project: Clinical Trial

• A Phase 2, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants With Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

  Project: Clinical Trial

• A Phase 2, Multicenter, Single-arm Study of Retreatment With Brentuximab Vedotin in Subjects With Relapsed or Refractory Classic Hodgkin Lymphoma (cHL) or CD30-expressing Peripheral T Cell Lymphoma (PTCL)

  Pingali, S. R., Ganguly, S., Petkova, J., Rice, L. & Shah, S.

  Project: Clinical Trial

• A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of K0706 in Subjects With Early Parkinson's Disease

  Ondo, W. G. & Waln, O.

  10/22/19 → …

  Project: Clinical Trial

• A Phase 2, Two-Part, Multicenter Study of HTX-011 in Spinal Surgery

  Barber, S., Holman, P., Huang, M. & Moore, L. W.

  Project: Clinical Trial

• A Phase 2/3, Randomized, Double Blind, Placebo Controlled, Multicenter Study to Evaluate the Efficacy and Safety of FP-025 in Patients With Severe to Critical COVID 19 With Associated Acute Respiratory Distress Syndrome (ARDS)

  Zainab, A. & Hsu, S. H.

  Project: Clinical Trial

• A Phase 2 Open-label Study of Brentuximab Vedotin in Front-line Therapy of Hodgkin Lymphoma (HL) an dCD30-expressing Peripheral T-cell Lymphoma (PTCL) in Older Patients or Patients With Significant Comorbidities Ineligible for Standard Chemotherapy

  Pingali, S. R., Ganguly, S., Petkova, J., Rice, L. & Shah, S.

  Project: Clinical Trial

• A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, 27-Week Trial to Evaluate the Efficacy, Safety, and Tolerability of Two Fixed Doses of Tavapadon in Early Parkinson's Disease (TEMPO-1 TRIAL)

  Ondo, W. G. & Waln, O.

  8/6/20 → …

  Project: Clinical Trial

• A Phase 3, Multi-center, Randomized, Double-blind, Parallel-group, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Sodium Oligomannate (GV-971) in Treatment of Mild to Moderate Alzheimer's Disease (GREEN MEMORY: GREen Valley 971 EvaluatioN Memory)

  Masdeu, J. C. & Faridar, A.

  9/13/21 → …

  Project: Clinical Trial

• A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL, ACTIVE-CONTROLLED STUDY OF TRASTUZUMAB DERUXTECAN (T-DXd) VERSUS TRASTUZUMAB EMTANSINE (T-DM1) IN SUBJECTS WITH HIGH-RISK HER2-POSITIVE PRIMARY BREAST CANCER WHO HAVE RESIDUAL INVASIVE DISEASE IN BREAST OR

  7/6/21 → 7/5/31

  Project: Non Profit

• A Phase 3, Randomized, Controlled Study of Prophylactic and On-demand Treatment of cTTP With BAX 930 (rADAMTS13)

  Rice, L.

  1/3/20 → …

  Project: Clinical Trial

• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

  Shroff, S., Appel, S. H., Greene, E. P. & Thonhoff, J. R.

  10/18/19 → …

  Project: Clinical Trial

• A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-322)

  Shah, S., Ganguly, S., Petkova, J., Pingali, S. R. & Rice, L.

  Project: Clinical Trial

• A Phase I/II Open-Label, Safety And Preliminary Efficacy Study Of MRx0518 In Combination With Pembrolizumab In Patients With Advanced Malignancies Who Have Progressed On PD-1/PD-L1 Inhibitors

  Bernicker, E. H., Heyne, K. & Zhang, J.

  9/25/20 → …

  Project: Clinical Trial

• A Phase II/III Trial of Neoadjuvant FOLFOX w/ Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection w/ Total Mesorectal Excisio

  Bernicker, E. H., Darcourt, J. & Singh, M.

  University of Michigan

  6/11/13 → 6/10/38

  Project: Non Profit

• A Phase II and Biomarker Study of Dual VEGF/PD-L1 Blockade in Neoadjuvant Setting in Resectable Hepatocellular Carcinoma Patients

  Ghobrial, R. M., Abdelrahim, M. & Kodali, S.

  4/1/21 → 3/31/26

  Project: Federal Funding Agencies

• A Phase IIa randomized, double-blind, placebo-controlled study of the effects of L-serine on Mild Cognitive Impairment (MCI)

  Roman, G. C., Masdeu, J. C. & Pascual, B.

  Project: Clinical Trial

• A Phase IIb/III, Randomized, Double-blind, Placebo-controlled Trial of Troriluzole in Adult Subjects With Spinocerebellar Ataxia

  Ashizawa, T., Ondo, W. G. & Waln, O.

  1/25/17 → …

  Project: Clinical Trial

• A Phase II Clinical tRial of neoADjuVant sAsanlimab and stereotaCtiC body radIatioN thErapy as an in situ vaccine for cisplatin-ineligible Muscle Invasive Bladder Cancer (RAD VACCINE MIBC)

  Satkunasivam, R., Chen, S., Esnaola, N. F., Farach, A. M., Teh, B. S. & Zhang, J.

  1/20/22 → …

  Project: Clinical Trial

• A Phase III, Long-Term, Randomized, Double-blind, Placebo-controlled Trial of Troriluzole in Adult Subjects With Spinocerebellar Ataxia.

  Ashizawa, T. & Ondo, W. G.

  5/10/19 → …

  Project: Clinical Trial

• A Phase III, Multicenter, Open-Label, Extension Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow® Device plus Standard of Care in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post Single or Double Lung Transplantation (BT-L-CsA-303-FU (BOSTON-3))

  Goodarzi, A., Yau, S. W. & Youssef, J. G.

  5/27/20 → …

  Project: Clinical Trial

• A phase III, multicenter, randomized, study of atezolizumab/placebo administered in combination with paclitaxel, carboplatin, and bevacizumab to patients with newly-diagnosed stage III or stage IV ovarian, fallopian tube, or primary peritoneal cancer

  Kamat, A. A., Alaniz, A., Bernicker, E. H., Darcourt, J., Heyne, K., Singh, M., Suri, A. & Zaid, T.

  3/13/18 → 3/12/43

  Project: Non Profit

• A Phase III, Open-Label, Randomized Study to Investigate the Efficacy and Safety of Atezolizumab (Anti-PD-L1 Antibody) Compared With Best Supportive Care Following Adjuvant Cisplatin-Based Chemotherapy in Patients With Completely Resected Stage IB-IIIA

  Bernicker, E. H., Darcourt, J., Heyne, K., Singh, M. & Zhang, J.

  Project: Clinical Trial