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  UCB - PD0053 Double-Blind, Placebo-Controlled, Randomized, 18-Month Phase 2a Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Oral UCB0599 in Study Participants With Early Parkinson's Disease

  Waln, O. & Ondo, W. G.

  7/21/21 → …

  Project: Clinical Trial

• Phase II_FulvestrantAbemaciclib_ERHer2-metastaticBreastCancer_HMRIEli Lilly

  Chang, J. C., Darcourt, J., Geyer, C. E. & Niravath, P. A.

  7/15/21 → …

  Project: Clinical Trial

• Sepsis Prediction with Deep Learning and Wearable Monitoring Patch'd

  Pingali, S. R., Gotur, D. B., Jones, S. L. & Masud, F. N.

  7/14/21 → …

  Project: Clinical Trial

• VISTAS VLX-301

  Victor, III, D. W. & Shetty, A.

  7/9/21 → …

  Project: Clinical Trial

• Targeting the HIV-1 Reservoir in Myeloid Cells

  Wang, J.

  7/6/21 → 5/31/26

  Project: Federal Funding Agencies

• A versatile reporter for visualization of myelin plasticity in the genetically modified rat

  Horner, P. J.

  7/1/21 → 12/31/22

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining itscontributions to post-transcriptional gene regulation (Same as parent grant)

  Kiss, D. L.

  7/1/21 → 6/30/23

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining its contributions to post-transcriptional gene regulation (Same as parent grant)

  Kiss, D. L.

  7/1/21 → 6/30/23

  Project: Federal Funding Agencies

• Assessing Energy Needs, Nutritional Status, and Physical Functioning in Patients with Hepatocellular Carcinoma (HCC)

  6/29/21 → …

  Project: Clinical Trial

• SH:HighLife Transseptal Transcatheter Mitral Valve Replacement HighLife Medical

  Goel, S., Faza, N., Kleiman, N., Little, S. H. & Reardon, M. J.

  6/29/21 → …

  Project: Clinical Trial

• MG_ALXN-MG-501_Registry Long-Term, Observational, Registry of Patients With Generalized Myasthenia Gravis Who Have Received Treatment With Complement C5 Inhibition Therapies

  Greene, E. P., Liao, B., Shroff, S. & Thonhoff, J. R.

  6/28/21 → …

  Project: Clinical Trial

• AOCT - Intuitive da Vinci SP in Colorectal Surgical Procedures

  6/28/21 → …

  Project: Clinical Trial

• SH-REPAIR MR - Mitraclip Device vs. Surgical Repair for Mitral Regurgitation Abbott Percutaneous MitraClipTM Device or Surgical Mitral Valve REpair in PAtients with PrImaRy Mitral Regurgitation who are Candidates for Surgery (REPAIR MR)

  Goel, S., Bhimaraj, A., Faza, N., Guha, A., Kassi, M., Kleiman, N., Lawrie, G. M., Little, S. H., Reardon, M. J. & Yousefzai, R.

  6/28/21 → …

  Project: Clinical Trial

• MERCK MK-5475 in PAH, Phase 23 A Phase 2/3, Multicenter, Randomized, Double-blind, Placebo-Controlled, Adaptive Design Study to Evaluate the Efficacy and Safety of MK-5475 in Adults With Pulmonary Arterial Hypertension

  Sahay, S. & Safdar, Z.

  6/28/21 → …

  Project: Clinical Trial

• Mitochondrial function in symptomatic chronic COVID-19 patients COVID-19 Associated Mitochondria Functional Changes in Subjects with Post-Acute Sequelae of SARS-CoV-2 Infections (PASC)

  Hamilton, D. J. & Youssef, J. G.

  6/16/21 → …

  Project: Clinical Trial

• Phase II_CMP-001Pembrolizumab_Head and Neck SCC_Checkmate CMP-001-007

  Zhang, J., Bernicker, E. H. & Heyne, K.

  6/14/21 → …

  Project: Clinical Trial

• NASH_CC-90001

  Shetty, A. & Victor, III, D. W.

  6/14/21 → …

  Project: Clinical Trial

• Studies of a new checkpoint regulator in the control of intestinal inflammation

  Zhang, Z. & Li, X. C.

  6/7/21 → 5/31/26

  Project: Federal Funding Agencies

• Molecular Mechanism of Virulence Regulation in Streptococcus Pyogenes

  Kumaraswami, M. & Olsen, R. J.

  6/7/21 → 5/31/26

  Project: Federal Funding Agencies

• Phase 3_NavitoclaxRuxolitinib_Myelofibrosis_Abbvie M20-178 Transform-2

  Shah, S., Darcourt, J., Pingali, S. R. & Rice, L.

  6/7/21 → …

  Project: Clinical Trial

• Phase II Open Label, Study of IMMU-132 in Metastatic Urothelial Cancer After Failure of Platinum-Based Regimen or Anti-PD-1/ PD-L1 Based Immunotherapy

  Darcourt, J., Abdelrahim, M., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A. & Singh, M.

  6/7/21 → …

  Project: Clinical Trial

• Compassionate Use Program_Tebentafusp_HMRIMelanoma_Immunocore

  Bernicker, E. H. & Singh, M.

  6/7/21 → …

  Project: Clinical Trial

• Novel Stem Cell Immunotherapy for MDR-Tuberculosis

  Jagannath, C., Gao, R. & Khan, A.

  6/4/21 → 5/31/26

  Project: Federal Funding Agencies

• Novel Determinants of Streptococcus Pyogenes Virulence and Protective Immunity in the Primate Oropharynx: A Genome-wide Strategy

  Musser, J. M., Nagueh, S., Olsen, R. J. & Zhu, L.

  6/1/21 → 5/31/22

  Project: Federal Funding Agencies

• The immunosuppressive function of secretory IgM in tumor-bearing mice

  Tang, C. A. & Yin, Z.

  6/1/21 → 5/31/24

  Project: Federal Funding Agencies

• A Novel M2 Lipogenic Macrophage Associated with Fracture Callus are Altered in Type 2 Diabetes

  Davis, B.

  6/1/21 → 5/31/23

  Project: Federal Funding Agencies

• CVL-751-PD-004 (TEMPO-1 TRIAL)

  Ondo, W. G. & Waln, O.

  5/25/21 → …

  Project: Clinical Trial

• Houston Alzheimer Disease Study HADS

  Masdeu, J. C., Appel, S. H., Faridar, A., Fujita, M., Karmonik, C., Nakawah, M. O., Pascual, B., Roman, G. C. & Wong, S. T.

  5/17/21 → …

  Project: Clinical Trial

• Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer¿s Disease

  Wong, S. T., Sheng, J. & Yin, Z.

  5/15/21 → 4/30/26

  Project: Federal Funding Agencies

• Lung Microphysiological Systems to Model Select Agent Bacteria and Viral Infection and Test Candidate Countermeasures

  Nichols, J.

  5/13/21 → 9/18/21

  Project: Federal Funding Agencies

• Brachytherapy for Bladder Preservation in Muscle Invasive Bladder Cancer A Phase 1 Study of Robotic High Dose Rate (HDR) Brachytherapy for Bladder Preservation in Muscle Invasive Bladder Cancer

  Satkunasivam, R., Butler, E. B., Darcourt, J., Farach, A. M., Gonzalez, R., Gupta, N., Miles, B. J., Singh, M. & Zhang, J.

  5/13/21 → …

  Project: Clinical Trial

• LOW DOSE CT LUNG CANCER SCREENING REFINING LOW DOSE CT LUNG CANCER SCREENING USING BLOOD-BASED BIOMARKERS AND RADIOMICS

  Esnaola, N. F., Bernicker, E. H., El-Zein, R. & Nance, Jr., J. W.

  5/7/21 → …

  Project: Clinical Trial

• VAS-Retrospective Chart Review of AV Fistulae Patency Laminate Medical Technologies A multicenter retrospective observational study to evaluate primary patency of arteriovenous fistulae 6 months post-surgery

  Peden, E. K.

  5/4/21 → …

  Project: Clinical Trial

• African trypanosome parasites: a new tool to unveil potential immunological strategies totarget CLL

  Hu, A.

  5/3/21 → 4/30/23

  Project: Federal Funding Agencies

• Phase II_PevonedistatVenetoclaxAzacitidine_AML_Pevonedistat-2002Takeda A Randomized, Open-label, Controlled, Phase 2 Study of Pevonedistat, Venetoclax, and Azacitidine Versus Venetoclax Plus Azacitidine in Adults With Newly Diagnosed Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy

  Shah, S., Darcourt, J., Ganguly, S., Petkova, J., Pingali, S. R. & Rice, L.

  4/30/21 → …

  Project: Clinical Trial

• Phase III_GDC-9545 RO7197597_Breast Cancer_Roche BO41843 A Phase III Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Efficacy and Safety of GDC-9545 Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Patients With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer

  Niravath, P. A., Chang, J. C., Darcourt, J. & Geyer, C. E.

  4/28/21 → …

  Project: Clinical Trial

• EP-CATALYST - Amulet Device Compared to NOACs for A-Fib Treatment Abbott

  Valderrábano, M., Dave, A., Goel, S., Mathuria, N. & Schurmann, P.

  4/19/21 → …

  Project: Clinical Trial

• GOG-3044 LAE002INT2001

  Kamat, A. A., Alaniz, A., Darcourt, J., Singh, M., Suri, A. & Zaid, T.

  4/16/21 → …

  Project: Clinical Trial

• S100A4 mediated immune suppression in GBM

  Yun, K. & Xu, S.

  4/1/21 → 1/31/26

  Project: Federal Funding Agencies

• Targeting ER stress response in B-cell chronic lymphocytic leukemia

  Hu, A., Pingali, S. R. & Tang, C. A.

  4/1/21 → 3/31/24

  Project: Federal Funding Agencies

• A Phase II and Biomarker Study of Dual VEGF/PD-L1 Blockade in Neoadjuvant Setting in Resectable Hepatocellular Carcinoma Patients

  Ghobrial, R. M. & Abdelrahim, M.

  4/1/21 → 3/31/26

  Project: Federal Funding Agencies

• Targeting IRE-1a/XBP-1 Axis for Control of Chronic GVHD and Leukemia Relapse

  Hu, A.

  4/1/21 → 6/30/22

  Project: Federal Funding Agencies

• IL2 Plus Abatacept in AD

  Faridar, A., Appel, S. H. & Masdeu, J. C.

  3/24/21 → …

  Project: Clinical Trial

• Phase II_IL-12 and L-NMMA_Triple Negative Breast Cancer_Merck INTEGRAL study

  Darcourt, J., Geyer, C. E., Niravath, P. A. & Venta, L. A.

  3/12/21 → …

  Project: Clinical Trial

• Donanemab in Early Symptomatic Alzheimer's Disease - AACI

  Masdeu, J. C., Faridar, A., Nakawah, M. O. & Pascual, B.

  3/12/21 → …

  Project: Clinical Trial

• CHEST CYTOSTORM study

  Gotur, D. B., Chang, J. C., Ensor, Jr., J. E., Pingali, S. R. & Rosato, R. R.

  3/8/21 → …

  Project: Clinical Trial

• FMT for recurrent C. difficile infection

  Quigley, E. M. & Abraham, B. P.

  3/8/21 → …

  Project: Clinical Trial

• Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer

  Wang, Z. & Cristini, V.

  3/4/21 → 2/28/26

  Project: Federal Funding Agencies

• HF-CAEL 101-301 Phase 3 in Treatment of Stage IIIb AL Amyloidosis Caelum Biosciences

  Trachtenberg, B. H., Bhimaraj, A., Guha, A., Hussain, I., Kassi, M., Kim, J. H., Rice, L. & Yousefzai, R.

  3/3/21 → …

  Project: Clinical Trial

• HF-CAEL 101-302 Phase 3 in Treatment of Stage IIIa AL Amyloidosis Caelum Biosciences

  Trachtenberg, B. H., Bhimaraj, A., Guha, A., Hussain, I., Kassi, M., Kim, J. H., Rice, L. & Yousefzai, R.

  3/3/21 → …

  Project: Clinical Trial