Projects per year
Personal profile
Personal profile
Dr. Wang is an expert at the forefront of research in the fields of computational biology, modeling-aided drug target discovery, biophysical modeling of drug transport, and multiscale cancer modeling. Dr. Wang has developed expertise in both computational and translational research, and has successfully acted as an intermediary, catalyst, and team leader at the intersection of mathematics/engineering and the biology/medical fields. This intermediary role between medical and mathematical fields is of particular importance, facilitating discoveries that are only possible through a joining of these distinct but important research fields.
Research interests
Dr. Wang’s research spans a broad spectrum of applied mathematics, probability modeling, and systems biology and medicine. Dr. Wang’s research focuses on integrating mathematical, physical, and statistical methods with experimental investigations and patient data analysis to quantitatively study tumor progression and invasion, to help improve prediction of treatment efficacy and optimize treatment planning. Furthermore, he has been developing practical mathematical tools that can potentially be used by doctors in the clinic to predict the outcome for each individual patient prior to actual treatment.
External positions
Associate Professor of Research in Physiology and Biophysics, Weill Cornell Medical College
Dec 12 2019 → …
Research Area Keywords
- Cancer
- Imaging & Radiology
- Nanomedicine
- Precision Medicine
- Regenerative Medicine
- Systems Medicine & Bioinformatics
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Network
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Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer
3/4/21 → 2/28/26
Project: Federal Funding Agencies
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miR-155 targeted therapeutics for precision medicine in lung cancer
8/3/18 → 7/31/23
Project: Federal Funding Agencies
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A Targeted Nanomedicine Prototype Against Enzalutamide-resistant Prostate Cancer
8/1/18 → 7/31/23
Project: Federal Funding Agencies
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Imaging and Molecular correlates of progression in cystic neoplasms of the pancreas
9/1/18 → 8/31/21
Project: Federal Funding Agencies
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A new multiscale methodology and application to tumor growth modeling
7/1/18 → 5/31/20
Project: Federal Funding Agencies
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A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection
Dogra, P., Schiavone, C., Wang, Z., Ruiz-Ramírez, J., Caserta, S., Staquicini, D. I., Markosian, C., Wang, J., Sostman, H. D., Pasqualini, R., Arap, W. & Cristini, V., May 25 2023, (E-pub ahead of print) In: JCI insight.Research output: Contribution to journal › Article › peer-review
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Prospective Subunit Nanovaccine against Mycobacterium tuberculosis Infection─Cubosome Lipid Nanocarriers of Cord Factor, Trehalose 6,6' Dimycolate.
Sarkar, S., Mishra, A., Periasamy, S., Dyett, B., Dogra, P., Ball, A. S., Yeo, L. Y., White, J. F., Wang, Z., Cristini, V., Jagannath, C., Khan, A., Soni, S. K., Drummond, C. J. & Conn, C. E., Jun 1 2023, (E-pub ahead of print) In: ACS Applied Materials and Interfaces.Research output: Contribution to journal › Article › peer-review
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Cellular Automata Modelling Reveals Dynamics of Wound Healing Assay
Migliaccio, G., Ferraro, R., Wang, Z., Cristini, V., Dogra, P. & Caserta, S., Sep 26 2022, In: SSRN Electronic Journal.Research output: Contribution to journal › Article
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Computational approaches for multiscale modeling
Butner, J., Dogra, P., Cristini, V., Deisboeck, T. S. & Wang, Z., Dec 2022, (Accepted/In press) Encyclopedia of Cell Biology. Bradshaw, RA., Stahl, PD. & Hart, J. (eds.). 2nd ed. ElsevierResearch output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
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Dedifferentiation-mediated stem cell niche maintenance in early-stage ductal carcinoma in situ progression: insights from a multiscale modeling study
Butner, J. D., Dogra, P., Chung, C., Ruiz-Ramírez, J., Nizzero, S., Plodinec, M., Li, X., Pan, P. Y., Chen, S. H., Cristini, V., Ozpolat, B., Calin, G. A. & Wang, Z., May 2022, In: Cell death & disease. 13, 5, 485.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Prizes
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2019 Travel award for the Biophysical Society Annual Meeting
Wang, Zhihui (Recipient), Mar 2019
Prize: Prize (including medals and awards)
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A Multiscale Agent-Based Model of Ductal Carcinoma in Situ
Butner, J. (Recipient) & Wang, Zhihui (Recipient), May 2020
Prize: Other distinction
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A multiscale mathematical model to study nanomedicine delivery in solid tumors
Dogra, Prashant (Recipient) & Wang, Zhihui (Recipient), Nov 2019
Prize: Other distinction
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