Projects per year
Personal profile
Personal profile
Dr. Wang is an expert at the forefront of research in the fields of computational biology, modeling-aided drug target discovery, biophysical modeling of drug transport, and multiscale cancer modeling. Dr. Wang has developed expertise in both computational and translational research, and has successfully acted as an intermediary, catalyst, and team leader at the intersection of mathematics/engineering and the biology/medical fields. This intermediary role between medical and mathematical fields is of particular importance, facilitating discoveries that are only possible through a joining of these distinct but important research fields.
Research interests
Dr. Wang’s research spans a broad spectrum of applied mathematics, probability modeling, and systems biology and medicine. Dr. Wang’s research focuses on integrating mathematical, physical, and statistical methods with experimental investigations and patient data analysis to quantitatively study tumor progression and invasion, to help improve prediction of treatment efficacy and optimize treatment planning. Furthermore, he has been developing practical mathematical tools that can potentially be used by doctors in the clinic to predict the outcome for each individual patient prior to actual treatment.
External positions
Associate Professor of Research in Physiology and Biophysics, Weill Cornell Medical College
Dec 12 2019 → …Research Area Keywords
- Cancer
- Imaging & Radiology
- Nanomedicine
- Precision Medicine
- Regenerative Medicine
- Systems Medicine & Bioinformatics
Fingerprint
- 1 Similar Profiles
Network
Projects
-
Imaging and Molecular correlates of progression in cystic neoplasms of the pancreas
9/1/18 → 8/31/21
Project: Federal Funding Agencies
-
miR-155 targeted therapeutics for precision medicine in lung cancer
8/3/18 → 7/31/23
Project: Federal Funding Agencies
-
A Targeted Nanomedicine Prototype Against Enzalutamide-resistant Prostate Cancer
8/1/18 → 7/31/23
Project: Federal Funding Agencies
-
Targeted Therapeutics for ovarian cancer and its microenvironment treatment and theoretical modeling
6/1/18 → 5/31/22
Project: Federal Funding Agencies
-
A new multiscale methodology and application to tumor growth modeling
7/1/18 → 5/31/20
Project: Federal Funding Agencies
Research Output
-
A mathematical model to predict nanomedicine pharmacokinetics and tumor delivery
Dogra, P., Butner, J. D., Ruiz Ramírez, J., Chuang, Y. L., Noureddine, A., Jeffrey Brinker, C., Cristini, V. & Wang, Z., 2020, In : Computational and Structural Biotechnology Journal. 18, p. 518-531 14 p.Research output: Contribution to journal › Article
4 Scopus citations -
A mechanistic immunotherapy model provides patient-specific quantification of immune response and associated long-term tumor burden
Butner, J., Wang, Z., Elganainy, D., Plodinec, M., Calin, G. A., Dogra, P., Nizzero, S., Ruiz Ramírez, J., Chung, C., Koay, E. J., Welsh, J., Hong, D. S. & Cristini, V., Dec 2020, (Accepted/In press) In : Nature Biomedical Engineering.Research output: Contribution to journal › Article
-
Graph theory in the study of Alzheimer’s disease progression
Pelaez, M., Dogra, P., Wang, Z. & Cristini, V., Mar 10 2020, Open Access Government.Research output: Book/Report › Other report
-
Image-guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies
Dogra, P., Butner, J. D., Nizzero, S., Ruiz Ramírez, J., Noureddine, A., Peláez, M. J., Elganainy, D., Yang, Z., Le, A. D., Goel, S., Leong, H. S., Koay, E. J., Brinker, C. J., Cristini, V. & Wang, Z., Sep 1 2020, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 12, 5, e1628.Research output: Contribution to journal › Review article
1 Scopus citations -
Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection
Zaid, M., Elganainy, D., Dogra, P., Dai, A., Widmann, L., Fernandes, P., Wang, Z., Pelaez, M. J., Ramirez, J. R., Singhi, A. D., Dasyam, A. K., Brand, R. E., Park, W. G., Rahmanuddin, S., Rosenthal, M. H., Wolpin, B. M., Khalaf, N., Goel, A., Von Hoff, D. D., Tamm, E. P. & 3 others, , Dec 2 2020, In : Frontiers in Oncology. 10, 596931.Research output: Contribution to journal › Article
Open Access
Prizes
-
2019 Travel award for the Biophysical Society Annual Meeting
Wang, Zhihui (Recipient), Mar 2019
Prize: Prize (including medals and awards)
-
A Multiscale Agent-Based Model of Ductal Carcinoma in Situ
Joseph Butner (Recipient) & Wang, Zhihui (Recipient), May 2020
Prize: Other distinction
-
-
-