Research outputs

  1. 2019
  2. Discovery of class I histone deacetylase inhibitors based on romidpesin with promising selectivity for cancer cells

    Zhang, K., Hamilton, D. J., Li, Z. & Jiang, S., Nov 29 2019, In : Future Medicinal Chemistry.

    Research output: Contribution to journalArticle

  3. Vulnerable Atherosclerotic Plaque Imaging by Small-Molecule High-Affinity Positron Emission Tomography Radiopharmaceutical

    Yang, Z., Li, F., Yelamanchili, D., Zeng, Z., Rosales, C., Youker, K. A., Shen, H., Ferrari, M., Mahmarian, J., Pownall, H. J., Hamilton, D. J. & Li, Z., Aug 1 2019, In : advanced therapeutics. 2, 8

    Research output: Contribution to journalArticle

  4. Investigation of parameters that determine Nano-DC vaccine transport

    Zhang, J., Mai, J., Li, F., Shen, J., Zhang, G., Li, J., Hinkle, L. E., Lin, D., Liu, X., Li, Z., Wang, R., Mittendorf, E. A., Ferrari, M. & Shen, H., Jun 1 2019, In : Biomedical Microdevices. 21, 2, 39.

    Research output: Contribution to journalArticle

  5. Single-Molecule Force Measurement Guides the Design of Multivalent Ligands with Picomolar Affinity

    Yang, Z., Jiang, S., Li, F., Qiu, Y., Gu, J., Pettigrew, R. I., Ferrari, M., Hamilton, D. J. & Li, Z., Jan 1 2019, In : Angewandte Chemie - International Edition.

    Research output: Contribution to journalArticle

  6. Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles

    Nizzero, S., Li, F., Zhang, G., Venuta, A., Borsoi, C., Mai, J., Shen, H., Wolfram, J., Li, Z., Blanco, E. & Ferrari, M., Jan 1 2019, In : Acta Biomaterialia.

    Research output: Contribution to journalArticle

  7. 2018
  8. Targeted Maytansinoid Conjugate Improves Therapeutic Index for Metastatic Breast Cancer Cells

    Jiang, Z., Yang, Z., Li, F., Li, Z., Fishkin, N. & Burgess, K., Sep 19 2018, In : Bioconjugate Chemistry. 29, 9, p. 2920-2926 7 p.

    Research output: Contribution to journalArticle

  9. Developing VEGF receptors targeted molecular probes for PET imaging of vulnerable atherosclerotic plaques

    Yang, Z., Li, F. & Li, Z., May 1 2018, In : Journal of Nuclear Medicine. 59, supplement 1, p. 1526 1 p.

    Research output: Contribution to journalArticle

  10. A zwitterionic near-infrared dye linked TrkC targeting agent for imaging metastatic breast cancer

    Yang, Z., Usama, S. M., Li, F., Burgess, K. & Li, Z., Jan 1 2018, In : MedChemComm. 9, 10, p. 1754-1760 7 p.

    Research output: Contribution to journalArticle

  11. Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway

    Wang, T., Wu, X., Guo, C., Zhang, K., Xu, J., Li, Z. & Jiang, S., Jan 1 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

    Research output: Contribution to journalArticle

  12. 2017
  13. A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery

    Wolfram, J., Nizzero, S., Liu, H., Li, F., Zhang, G., Li, Z., Shen, H., Blanco, E. & Ferrari, M., Oct 23 2017, In : Scientific Reports. 7, 1, p. 13738

    Research output: Contribution to journalArticle

  14. The Isomeric Preference of an Atypical Dopamine Transporter Inhibitor Contributes to Its Selection of the Transporter Conformation

    Abramyan, A. M., Stolzenberg, S., Li, Z., Loland, C. J., Noé, F. & Shi, L., Aug 16 2017, In : ACS Chemical Neuroscience. 8, 8, p. 1735-1746 12 p.

    Research output: Contribution to journalArticle

  15. The role of transmembrane segment 5 (TM5) in Na2 release and the conformational transition of neurotransmitter: sodium symporters toward the inward-open state

    Stolzenberg, S., Li, Z., Quick, M., Malinauskaite, L., Nissen, P., Weinstein, H., Javitch, J. A. & Shi, L., May 5 2017, In : Journal of Biological Chemistry. 292, 18, p. 7372-7384 13 p.

    Research output: Contribution to journalArticle

  16. Pet Imaging and its Application in Cardiovascular Diseases

    Li, Z., Gupte, A. A., Zhang, A. & Hamilton, D. J., Mar 1 2017, In : Methodist DeBakey Cardiovascular Journal. 13, 1, p. 29-33 5 p.

    Research output: Contribution to journalReview article

  17. An agent for optical imaging of TrkC-expressing, breast cancer

    Kamkaew, A., Li, F., Li, Z. & Burgess, K., 2017, In : MedChemComm. 8, 10, p. 1946-1952 7 p.

    Research output: Contribution to journalArticle

  18. 2016
  19. Prediction and Early Evaluation of Anticancer Therapy Response: From Imaging of Drug Efflux Pumps to Targeted Therapy Response

    Menga, Q., Li, Z. & Li, S., Nov 1 2016, In : Current Medicinal Chemistry. 23, 41, p. 4625-4638 14 p.

    Research output: Contribution to journalArticle

  20. Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities

    Bai, J., Liao, C., Liu, Y., Qin, X., Chen, J., Qiu, Y., Qin, D., Li, Z., Tu, Z. C. & Jiang, S., Jun 23 2016, In : Journal of Medicinal Chemistry. 59, 12, p. 5766-5779 14 p.

    Research output: Contribution to journalArticle

  21. 2015
  22. Substrate-induced unlocking of the inner gate determines the catalytic efficiency of a neurotransmitter: Sodium symporter

    Billesbølle, C. B., Krüger, M. B., Shi, L., Quick, M., Li, Z., Stolzenberg, S., Kniazeff, J., Gotfryd, K., Mortensen, J. S., Javitch, J. A., Weinstein, H., Loland, C. J. & Gether, U., Oct 30 2015, In : Journal of Biological Chemistry. 290, 44, p. 26725-26738 14 p.

    Research output: Contribution to journalArticle

  23. Discovery of Novel Class i Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities

    Yao, Y., Tu, Z., Liao, C., Wang, Z., Li, S., Yao, H., Li, Z. & Jiang, S., Oct 8 2015, In : Journal of Medicinal Chemistry. 58, 19, p. 7672-7680 9 p.

    Research output: Contribution to journalArticle

  24. Unprecedented reactions: from epichlorohydrin to epoxyglycidyl substituted divinyl ether and its conversion into epoxyglycidyl propargyl ether

    Yao, Y., Li, Z., Qiu, Y., Bai, J., Su, J., Zhang, D. & Jiang, S., Sep 18 2015, In : Scientific Reports. 5, 14231.

    Research output: Contribution to journalArticle

  25. An HDAC-Targeted Imaging Probe LBH589-Cy5.5 for Tumor Detection and Therapy Evaluation

    Meng, Q., Liu, Z., Li, F., Ma, J., Wang, H., Huan, Y. & Li, Z., Jul 6 2015, In : Molecular Pharmaceutics. 12, 7, p. 2469-2476 8 p.

    Research output: Contribution to journalArticle

  26. Identification of a second substrate-binding site in solute-sodium symporters

    Li, Z., Lee, A. S. E., Bracher, S., Jung, H., Paz, A., Kumar, J. P., Abramson, J., Quick, M. & Shi, L., Mar 20 2015, In : Journal of Biological Chemistry. 290, 12, 1 p.

    Research output: Contribution to journalComment/debate

  27. One-step 18F labeling of non-peptidic bivalent integrin αvβ3 antagonist for cancer imaging

    Wang, W., Liu, Z. & Li, Z., Jan 21 2015, In : Bioconjugate Chemistry. 26, 1, p. 24-28 5 p.

    Research output: Contribution to journalArticle

  28. Identification of a second substrate-binding Site in solute-sodium symporters

    Li, Z., Lee, A. S. E., Bracher, S., Jung, H., Paz, A., Kumar, J. P., Abramson, J., Quick, M. & Shi, L., Jan 2 2015, In : Journal of Biological Chemistry. 290, 1, p. 127-141 15 p.

    Research output: Contribution to journalArticle

  29. An HDAC-Targeted Near-Infrared Probe LBH589-Cy5.5 for Tumor Detection and Therapy Evaluation

    Li, Z., 2015, In : Molecular Pharmacology. 12, 7, p. 2469-76

    Research output: Contribution to journalArticle

  30. 2014
  31. Long-term benefit of male circumcision to the reduction of urinary tract infections and genitourinary cancers in China

    Zhao, F. J., Li, P. S., Lü, N. Q., Lee, R., Peng, Y. F., Cheng, F., Li, Z., Xu, H. Q., Barone, M., Goldstein, M. & Xia, S. J., Nov 1 2014, In : Zhonghua nan ke xue = National journal of andrology. 20, 11, p. 969-977 9 p.

    Research output: Contribution to journalArticle

  32. Design, synthesis, and biological evaluation of 1, 3-disubstituted-pyrazole derivatives as new class I and IIb histone deacetylase inhibitors

    Yao, Y., Liao, C., Li, Z., Wang, Z., Sun, Q., Liu, C., Yang, Y., Tu, Z. & Jiang, S., Oct 30 2014, In : European Journal of Medicinal Chemistry. 86, p. 639-652 14 p.

    Research output: Contribution to journalArticle

  33. Specific and sensitive tumor imaging using biostable oligonucleotide aptamer probes

    Zeng, Z., Parekh, P., Li, Z., Shi, Z-Z., Tung, C-H. & Zu, Y., Jul 19 2014, In : Theranostics. 4, 9, p. 945-52 8 p.

    Research output: Contribution to journalArticle

  34. Biological evaluation of new mimetics of annonaceous acetogenins: Alteration of right scaffold by click linkage with aromatic functionalities

    Liu, Y., Xiao, Q., Liu, Y., Li, Z., Qiu, Y., Zhou, G. B., Yao, Z. J. & Jiang, S., May 6 2014, In : European Journal of Medicinal Chemistry. 78, p. 248-258 11 p.

    Research output: Contribution to journalArticle

  35. Identification of novel bivalent mimetics of annonaceous acetogenins via a scaffold-hopping strategy

    Liu, Y., Liu, Y., Li, Z., Zhou, G. B., Yao, Z. J. & Jiang, S., Apr 1 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 7, p. 1650-1653 4 p.

    Research output: Contribution to journalArticle

  36. A tyrosine kinase inhibitor-based high-affinity PET radiopharmaceutical targets vascular endothelial growth factor receptor

    Li, F., Jiang, S., Zu, Y., Lee, D. Y. & Li, Z., Jan 1 2014, In : Journal of Nuclear Medicine. 55, 9, p. 1525-1531 7 p.

    Research output: Contribution to journalArticle

  37. Biological evaluation of 2-methylpyrimidine derivatives as active pan Bcr-Abl inhibitors

    Zou, D., Qiu, Y., Tu, Z., Liao, C., Luo, J., Meng, Q., Yao, R., Li, Z. & Jiang, S., Jan 1 2014, In : Science China Chemistry. 57, 6, p. 823-832 10 p.

    Research output: Contribution to journalArticle

  38. Molecular imaging in tracking tumor-specific Cytotoxic T Lymphocytes (CTLs)

    Liu, Z. & Li, Z., Jan 1 2014, In : Theranostics. 4, 10, p. 990-1001 12 p.

    Research output: Contribution to journalArticle

  39. 2013
  40. The sodium/proline transporter PutP of Helicobacter pylori

    Rivera-Ordaz, A., Bracher, S., Sarrach, S., Li, Z., Shi, L., Quick, M., Hilger, D., Haas, R. & Jung, H., Dec 17 2013, In : PLoS ONE. 8, 12, e83576.

    Research output: Contribution to journalArticle

  41. Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells

    Pei, S., Minhajuddin, M., Callahan, K. P., Balys, M., Ashton, J. M., Neering, S. J., Lagadinou, E. D., Corbett, C., Ye, H., Liesveld, J. L., O'Dwyer, K. M., Li, Z., Shi, L., Greninger, P., Settleman, J., Benes, C., Hagen, F. K., Munger, J., Crooks, P. A., Becker, M. W. & 1 othersJordan, C. T., Nov 22 2013, In : Journal of Biological Chemistry. 288, 47, p. 33542-33558 17 p.

    Research output: Contribution to journalArticle

  42. Specific binding of modified ZD6474 (Vandetanib) monomer and its dimer with VEGF receptor-2

    Kim, Y. S., Li, F., O'neill, B. E. & Li, Z., Nov 20 2013, In : Bioconjugate Chemistry. 24, 11, p. 1937-1944 8 p.

    Research output: Contribution to journalArticle

  43. Multivalency of non-peptide integrin αvβ3 antagonist slows tumor growth

    Kim, Y. S., Li, F., Kong, R., Bai, Y., Li, K. C. P., Fan, Y., O'Neill, B. E. & Li, Z., Oct 7 2013, In : Molecular Pharmaceutics. 10, 10, p. 3603-3611 9 p.

    Research output: Contribution to journalArticle

  44. Novel 64Cu-labeled CUDC-101 for in vivo PET imaging of histone deacetylases

    Meng, Q., Li, F., Jiang, S. & Li, Z., Sep 12 2013, In : ACS Medicinal Chemistry Letters. 4, 9, p. 858-862 5 p.

    Research output: Contribution to journalArticle

  45. Molecular imaging probes for diagnosis and therapy evaluation of breast cancer

    Meng, Q. & Li, Z., Apr 3 2013, In : International Journal of Biomedical Imaging. 2013, 230487.

    Research output: Contribution to journalArticle

  46. Biological evaluation of new largazole analogues: Alteration of macrocyclic scaffold with click chemistry

    Li, X., Tu, Z., Li, H., Liu, C., Li, Z., Sun, Q., Yao, Y., Liu, J. & Jiang, S., Jan 10 2013, In : ACS Medicinal Chemistry Letters. 4, 1, p. 132-136 5 p.

    Research output: Contribution to journalArticle

  47. Imaging of genetically engineered T cells by PET using gold nanoparticles complexed to Copper-64

    Bhatnagar, P., Li, Z., Choi, Y., Guo, J., Li, F., Lee, D. Y., Figliola, M., Huls, H., Lee, D. A., Zal, T., Li, K. C. & Cooper, L. J. N., Jan 1 2013, In : Integrative Biology (United Kingdom). 5, 1, p. 231-238 8 p.

    Research output: Contribution to journalArticle

  48. 2011
  49. Highly efficient synthesis of phenols by copper-catalyzed hydroxylation of aryl iodides, bromides, and chlorides

    Yang, K., Li, Z., Wang, Z., Yao, Z. & Jiang, S., Aug 19 2011, In : Organic Letters. 13, 16, p. 4340-4343 4 p.

    Research output: Contribution to journalArticle

  50. New ligands that promote cross-coupling reactions between aryl halides and unactivated arenes

    Qiu, Y., Liu, Y., Yang, K., Hong, W., Li, Z., Wang, Z., Yao, Z. & Jiang, S., Jul 15 2011, In : Organic Letters. 13, 14, p. 3556-3559 4 p.

    Research output: Contribution to journalArticle

  51. Total synthesis of argyrins A and e

    Wu, W., Li, Z., Zhou, G. & Jiang, S., May 11 2011, In : Tetrahedron Letters. 52, 19, p. 2488-2491 4 p.

    Research output: Contribution to journalArticle

  52. Ligands for copper-catalyzed C-N bond forming reactions with 1 Mol% CuBr as catalyst

    Yang, K., Qiu, Y., Li, Z., Wang, Z. & Jiang, S., May 6 2011, In : Journal of Organic Chemistry. 76, 9, p. 3151-3159 9 p.

    Research output: Contribution to journalArticle

  53. Partially polymerized liposomes: Stable against leakage yet capable of instantaneous release for remote controlled drug delivery

    Qin, G., Li, Z., Xia, R., Li, F., O'Neill, B. E., Goodwin, J. T., Khant, H. A., Chiu, W. & Li, K. C., Apr 15 2011, In : Nanotechnology. 22, 15, 155605.

    Research output: Contribution to journalArticle

  54. Potent antitumor mimetics of annonaceous acetogenins embedded with an aromatic moiety in the left hydrocarbon chain part

    Xiao, Q., Liu, Y., Qiu, Y., Zhou, G., Mao, C., Li, Z., Yao, Z. J. & Jiang, S., Jan 27 2011, In : Journal of Medicinal Chemistry. 54, 2, p. 525-533 9 p.

    Research output: Contribution to journalArticle

  55. 2010
  56. Synthesis and evaluation of bivalent, peptidomimetic antagonists of the αvβ3 integrins

    Li, F., Jas, G. S., Qin, G., Li, K. & Li, Z., Nov 15 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 22, p. 6577-6580 4 p.

    Research output: Contribution to journalArticle

  57. Combining gene therapy and nanomedicine to enhance the therapeutic potential of T cells

    Choi, Y., Torikai, H., Lee, D. Y., Li, Z., Lo, D., Qin, G., Tung, C. H., Tasciotti, E., Raphael, R., Biswal, S. L., Ang, S., Lee, D. A., Li, K. C. & Cooper, L. J. N., Nov 9 2010, Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy - Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010. Vol. 3. p. 376-379 4 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  58. Total synthesis and biological evaluation of largazole and derivatives with promising selectivity for cancers cells

    Zeng, X., Yin, B., Hu, Z., Liao, C., Liu, J., Li, S., Li, Z., Nicklaus, M. C., Zhou, G. & Jiang, S., Mar 19 2010, In : Organic Letters. 12, 6, p. 1368-1371 4 p.

    Research output: Contribution to journalArticle

  59. Synthesis and evaluation of a near-infrared fluorescent non-peptidic bivalent integrin αvβ3 antagonist for cancer imaging

    Li, F., Liu, J., Jas, G. S., Zhang, J., Qin, G., Xing, J., Cotes, C., Zhao, H., Wang, X., Diaz, L. A., Shi, Z. Z., Lee, D. Y., Li, K. C. P. & Li, Z., Feb 17 2010, In : Bioconjugate Chemistry. 21, 2, p. 270-278 9 p.

    Research output: Contribution to journalArticle

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