Xuewu Liu, PhD

  • 5768 Citations
  • 42 h-Index
1990 …2020

Research output per year

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Personal profile

Personal profile

Dr. Xuewu Liu worked as an engineer in the optics industry for two years before undertaking postdoctoral training at the Indiana Center for Biological Microscopy at IUPUI Indianapolis. He then joined Ohio State University as a senior research associate in nanomedicine. He was appointed assistant professor of nanomedicine and biomedical engineering at the University of Texas Health Science Center in Houston in 2006. In 2010, Dr. Liu joined to The Methodist Hospital Research Institute, to direct the nanoengineering core.

Dr. Xuewu Liu is a leading scientist in silicon nanotechnology, with extensive experience in materials science, optics, microfabrication and nanomedicine. He directs research and development of silicon based biomedical nanotechnology, and coordinates a nanoengineering team to support biomedical research at the institute levels. The nanomedicine platforms he has developed include porous silicon particles, nanowire barcodes, an implantable nanochannel delivery system, nanowire enhanced nanofluidic devices, and nanoporous proteomic chips. Dr. Liu had been issued 8 US patents, and published over 100 peer-reviewed journal papers, of which >20 were highlighted as journal cover articles.

Research interests

Dr. Liu’s research focus is the development of silicon based nanotechnology platforms for prevention, diagnosis and treatment of human disease. His current interests include mass production of porous silicon particles, surface chemistry of porous silicon, nanowire theranostic platforms, multifunctional nanoparticles, and microfluidics devices for isolation and analysis of exosomes.

Education/Academic qualification

Postdoctoral Associate, Heart and Lung Research Institute

Biological Microscopy, Postdoctoral Associate, Indiana Center for Biological Microscopy, Indianapolis, IN

Nuclear Physics, MS, Jilin University

Physics, PhD, Kent State University

Research Area Keywords

  • Nanomedicine
  • Cancer

Free-text keywords

  • Silicon nanotechnology
  • Drug delivery nanoparticles
  • Theranostics
  • Biological microfluidics

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Projects

Research Output

An injectable nanoparticle generator enhances delivery of cancer therapeutics

Xu, R., Zhang, G., Mai, J., Deng, X., Segura-Ibarra, V., Wu, S., Shen, J., Liu, H., Hu, Z., Chen, L., Huang, Y., Koay, E., Huang, Y., Liu, J., Ensor, J. E., Blanco, E., Liu, X., Ferrari, M. & Shen, H., Apr 1 2016, In : Nature Biotechnology. 34, 4, p. 414-418 5 p.

Research output: Contribution to journalArticle

  • 157 Scopus citations

    Biocompatible PLGA-mesoporous silicon microspheres for the controlled release of bmp-2 for bone augmentation

    Minardi, S., Fernandez-Moure, J. S., Fan, D., Murphy, M. B., Yazdi, I. K., Liu, X., Weiner, B. K. & Tasciotti, E., Feb 2020, In : Pharmaceutics. 12, 2, 118.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Design and in vitro characterization of multistage silicon-PLGA budesonide particles for inflammatory bowel disease

    Leonard, F., Srinivasan, S., Liu, X., Collnot, E. M., Ferrari, M., Lehr, C. M. & Godin, B., Jun 1 2020, In : European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 61-72 12 p.

    Research output: Contribution to journalArticle

  • Electrostatically gated nanofluidic membrane for ultra-low power controlled drug delivery

    Di Trani, N., Silvestri, A., Sizovs, A., Wang, Y., Erm, D. R., Demarchi, D., Liu, X. & Grattoni, A., May 7 2020, In : Lab on a Chip. 20, 9, p. 1562-1576 15 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Hollow Mesoporous Metal-Organic Framework Microdisks via a Solid Template-Based Approach and Post-Synthetic Wet-Chemical Etching for Protein Loading

    Zhu, G., Cheng, L., Qi, R. & Liu, X., Apr 1 2020, In : ChemNanoMat. 6, 4, p. 589-597 9 p.

    Research output: Contribution to journalArticle