Projects per year
Personal profile
Personal profile
Dr. Xuewu Liu worked as an engineer in the optics industry for two years before undertaking postdoctoral training at the Indiana Center for Biological Microscopy at IUPUI Indianapolis. He then joined Ohio State University as a senior research associate in nanomedicine. He was appointed assistant professor of nanomedicine and biomedical engineering at the University of Texas Health Science Center in Houston in 2006. In 2010, Dr. Liu joined to The Methodist Hospital Research Institute, to direct the nanoengineering core.
Dr. Xuewu Liu is a leading scientist in silicon nanotechnology, with extensive experience in materials science, optics, microfabrication and nanomedicine. He directs research and development of silicon based biomedical nanotechnology, and coordinates a nanoengineering team to support biomedical research at the institute levels. The nanomedicine platforms he has developed include porous silicon particles, nanowire barcodes, an implantable nanochannel delivery system, nanowire enhanced nanofluidic devices, and nanoporous proteomic chips. Dr. Liu had been issued 8 US patents, and published over 100 peer-reviewed journal papers, of which >20 were highlighted as journal cover articles.
Research interests
Dr. Liu’s research focus is the development of silicon based nanotechnology platforms for prevention, diagnosis and treatment of human disease. His current interests include mass production of porous silicon particles, surface chemistry of porous silicon, nanowire theranostic platforms, multifunctional nanoparticles, and microfluidics devices for isolation and analysis of exosomes.
Education/Academic qualification
Postdoctoral Associate, Heart and Lung Research Institute
Biological Microscopy, Postdoctoral Associate, Indiana Center for Biological Microscopy, Indianapolis, IN
Nuclear Physics, MS, Jilin University
Physics, PhD, Kent State University
Research Area Keywords
- Nanomedicine
- Cancer
Free-text keywords
- Silicon nanotechnology
- Drug delivery nanoparticles
- Theranostics
- Biological microfluidics
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A tunable nanofluidic drug delivery platform for in vivo research
4/15/18 → 1/31/23
Project: Federal Funding Agencies
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Center for Immunotherapeutic Transport Oncophysics
Shen, H., Herzog, T., Kojic, M., Li, Z. (., Liu, X., Schrefler, B. A., Tasciotti, E., Wang, R. & Ziemys, A.
8/29/16 → 7/31/22
Project: Federal Funding Agencies
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Tumor vasculature-targeted nanotherapeutics for DNA damage response
Shen, H., Jenkins, N. A., Liu, X. & Mitra, S.
12/1/15 → 5/31/22
Project: Federal Funding Agencies
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A Nanodrug for the Cure of Metastatic Breast Cancer
Shen, H., Chang, J. C., Ensor, Jr., J. E. & Liu, X.
7/15/17 → 3/1/20
Project: Federal Funding Agencies
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Identification of novel immune targets and neoantigens for development of immunotherapy for breast cancer
Wang, R., Chang, J. C., Liu, X. & Wang, H.
12/1/16 → 11/30/19
Project: State
Research output
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An injectable nanoparticle generator enhances delivery of cancer therapeutics
Xu, R., Zhang, G., Mai, J., Deng, X., Segura-Ibarra, V., Wu, S., Shen, J., Liu, H., Hu, Z., Chen, L., Huang, Y., Koay, E., Huang, Y., Liu, J., Ensor, J. E., Blanco, E., Liu, X., Ferrari, M. & Shen, H., Apr 1 2016, In: Nature Biotechnology. 34, 4, p. 414-418 5 p.Research output: Contribution to journal › Article › peer-review
197 Scopus citations -
Long-acting tunable release of amlodipine loaded PEG-PCL micelles for tailored treatment of chronic hypertension
Di Trani, N., Liu, H. C., Qi, R., Viswanath, D. I., Liu, X., Chua, C. Y. X. & Grattoni, A., Oct 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 37, 102417.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Long-acting tunable release of amlodipine loaded PEG-PCL micelles for tailored treatment of chronic hypertension
Di Trani, N., Liu, H-C., Qi, R., Viswanath, D. I., Liu, X., Chua, C. Y. X. & Grattoni, A., Jun 22 2021, (E-pub ahead of print) In: Nanomedicine: Nanotechnology, Biology, and Medicine. 37, p. 102417Research output: Contribution to journal › Article › peer-review
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Platforms to test the temporospatial capabilities of carrier systems in delivering growth factors to benefit vascular bioengineering
Argueta, L. B., Niles, J. A., Sakamoto, J., Liu, X., Vega, S. P., Frank, L., Paessler, M., Cortiella, J. & Nichols, J. E., Aug 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 36, 102419.Research output: Contribution to journal › Article › peer-review
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Potentiating Antitumor Efficacy Through Radiation and Sustained Intratumoral Delivery of Anti-CD40 and Anti-PDL1
Liu, H. C., Viswanath, D. I., Pesaresi, F., Xu, Y., Zhang, L., Di Trani, N., Paez-Mayorga, J., Hernandez, N., Wang, Y., Erm, D. R., Ho, J., Susnjar, A., Liu, X., Demaria, S., Chen, S. H., Teh, B. S., Butler, E. B., Xuan Chua, C. Y. & Grattoni, A., Jun 1 2021, In: International Journal of Radiation Oncology Biology Physics. 110, 2, p. 492-506 15 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations