• 198 Citations
  • 8 h-Index

Research output per year

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Personal profile

Personal profile

Dr. Xin Yi is a board-certified clinical chemist (DABCC) with broad expertise in clinical chemistry, endocrinology testing, therapeutic drug monitoring, toxicology, and clinical pharmacogenetics. She is a fellow of the AACC’s National Academy of Clinical Biochemistry (NACB), and the Co-director of the ComACC postdoctoral fellowship program at Houston Methodist Hospital. Her clinical services include supervising the professional activities in the sections of general and special chemistry, point of care, and diagnostic immunology. Prior to her current position, she completed her postdoctoral fellowship training in clinical chemistry at the University of Chicago after completing her PhD in clinical-bioanalytical chemistry at Cleveland State University.

Research interests

Dr. Yi is interested in the application of new technologies, especially mass spectrometry and genetic analysis, in broader clinical diagnostic use. Her past research activities focused on developing novel diagnostic assays for hormone measurements using mass spectrometry, such as high-sensitive estradiol measurement to assist clinical management in pediatrics, men and postmenopausal women. Her studies in pharmacogenetics involved understanding the impact of genetic variations on therapeutic responses, such as responses to anticoagulant and antiplatelet agents, Warfarin and Clopidogrel. Her current research activities are focused on studying the expression of onco-proteins in tumor tissues using mass spectrometry, and utilizing this approach to aid cancer differential diagnoses and personalized cancer therapies.

Research Area Keywords

  • Infectious Disease & Pathology

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Research Output

  • 198 Citations
  • 8 h-Index
  • 13 Article
  • 1 Letter

Convalescent plasma anti-SARS-CoV-2 spike protein ectodomain and receptor binding domain IgG correlate with virus neutralization

Salazar, E., Kuchipudi, S. V., Christensen, P. A., Eagar, T., Yi, X., Zhao, P., Jin, Z., Long, S. W., Olsen, R. J., Chen, J., Castillo, B., Leveque, C., Towers, D., Lavinder, J. J., Gollihar, J., Cardona, J. A., Ippolito, G. C., Nissly, R. H., Bird, I., Greenawalt, D. & 14 others, Rossi, R. M., Gontu, A., Srinivasan, S., Poojary, I., Cattadori, I. M., Hudson, P., Josleyn, N. M., Prugar, L., Huie, K. E., Herbert, A. S., Bernard, D. W., Dye, J. M., Kapur, V. & Musser, J. M., Sep 10 2020, In : The Journal of clinical investigation.

Research output: Contribution to journalArticle

  • Pathology Trainee Redeployment and Education During the COVID-19 Pandemic: An Institutional Experience

    Monroig-Bosque, P. D. C., Hsu, J. W., Lin, M. S., Shehabeldin, A. N., Rogers, J. T., Kim, C. F., Kalsekar, A. G., Jin, Z., Cara, L. R., Barbieri, A. N., El-Zaatari, Z., Eskandari, G., Sheu, T. G., Tomsula, J. A., Long, S. W., Zieske, A. W., Leveque, C. M., Salazar, E., Mody, D. R., Schwartz, M. R. & 4 others, Cykowski, M. D., Yi, X., Powell, S. Z. & Thomas, J. S., 2020, In : Academic Pathology. 7

    Research output: Contribution to journalArticle

    Open Access
  • Development of a Nonradioactive Platelet Serotonin Uptake and Release Assay by Micro-Liquid Chromatography Tandem Mass Spectrometry Using Minimal Blood Volume

    Chan, S. L., Yi, X., Wysocki, E., Bridgman, R., Gutierrez, J., Mikrut, K., Leung, E. K. Y., Yeo, K. T. J. & Miller, J. L., Nov 4 2019, In : American Journal of Clinical Pathology. 152, 6, p. 718-724 7 p.

    Research output: Contribution to journalArticle

  • Quality control practices for chemistry and immunochemistry in a cohort of 21 large academic medical centers

    Rosenbaum, M. W., Flood, J. G., Melanson, S. E. F., Baumann, N. A., Marzinke, M. A., Rai, A. J., Hayden, J., Wu, A. H. B., Ladror, M., Lifshitz, M. S., Scott, M. G., Peck-Palmer, O. M., Bowen, R., Babic, N., Sobhani, K., Giacherio, D., Bocsi, G. T., Herman, D. S., Wang, P., Toffaletti, J. & 9 others, Handel, E., Kelly, K. A., Albeiroti, S., Wang, S., Zimmer, M., Driver, B., Yi, X., Wilburn, C. & Lewandrowski, K. B., Jul 3 2018, In : American Journal of Clinical Pathology. 150, 2, p. 96-104 9 p.

    Research output: Contribution to journalArticle

  • 12 Scopus citations

    Diiodothyropropionic acid (DITPA) cross-reacts with thyroid function assays on different immunoassay platforms

    Leung, E. K. Y., Yi, X., Refetoff, S. & Yeo, K. T. J., Jan 30 2016, In : Clinica Chimica Acta. 453, p. 203-204 2 p.

    Research output: Contribution to journalLetter



    Yi, Xin (Recipient), Apr 1 2016

    Prize: Fellowship awarded competitively

  • Lab Director Award

    Yi, Xin (Recipient), Feb 2016

    Prize: Prize (including medals and awards)