Personal profile

Dr. Xian C. Li is the director of the Immunobiology & Transplant Science Center at Houston Methodist Research Institute. Dr. Li served as deputy director of the Transplant Research Center at the Brigham and Women’s Hospital, a teaching hospital of Harvard Medical School before joining Houston Methodist. Dr. Li completed his medical training in China before joining the transplant team at London Health Science Center and the University of Western Ontario in Canada to do his doctoral training in transplant immunology. He then joined the research team at Harvard Medical School and Beth Israel Deaconess Medical Center in Boston, serving on the faculty until 2012.

Dr. Xian C. Li’s lab studies the fundamental mechanisms of transplant rejection and transplant tolerance, the goal of his team is to re-educate patients’ immune system to accept organ transplants without taking life-long immunosuppressive drugs.

Dr. Li has published more than 100 original papers, review articles, and book chapters in high impact journals. He is routinely invited to speak and serves on leadership committees for national and international scientific meetings. He has received awards in recognition of his contribution to transplant immunology including the American Society of Transplantation Young Investigator Award, the American Society of Transplantation Wyeth Basic Science Investigator Award, and AST/Wyeth Achievement Award.

Dr. Li is active in professional organizations and has served as a committee member for the basic science advisory council and grants executive committee of the American Society of Transplantation, a standing member of the American Association of Immunologists and The Transplantation Society, a member of Faculty 1000 for Immunology. He is also an elected member of the American Society for Clinical Investigation, has served as an associate editor for the Journal of Immunology, and is a standing member of the NIH Transplantation, Tolerance and Tumor Immunology study section. He serves on the editorial boards of Transplantation, Transplantation Research, and Cellular & Molecular Immunology.

Research interests

Dr. Li’s research program seeks to identify new mechanisms and pathways that control immune activation and immune regulation. His team develops new therapeutic protocols that support transplant survival without life-long immunosuppression. His lab has identified several molecular pathways that are critical to the immune recognition of transplants.

Keywords

    Research Area Keywords

  • Immunobiology & Inflammation
  • Transplantation

    Free-text keywords

  • Transplant, Immunology, Regulatory cell function, Allograft rejection, Tolerance induction

Fingerprint

T-Lymphocytes
Concept: T-Lymphocytes
Weight: 100%
Domain: Medicine & Life Sciences
Allografts
Concept: Allografts
Weight: 73%
Domain: Medicine & Life Sciences
Transplantation Tolerance
Concept: Transplantation Tolerance
Weight: 55%
Domain: Medicine & Life Sciences
Graft Rejection
Concept: Graft Rejection
Weight: 51%
Domain: Medicine & Life Sciences
Transplants
Concept: Transplants
Weight: 47%
Domain: Medicine & Life Sciences
Macrophages
Concept: Macrophages
Weight: 31%
Domain: Medicine & Life Sciences
Natural Killer Cells
Concept: Natural Killer Cells
Weight: 30%
Domain: Medicine & Life Sciences
Regulatory T-Lymphocytes
Concept: Regulatory T-Lymphocytes
Weight: 29%
Domain: Medicine & Life Sciences
Interleukin-2
Concept: Interleukin-2
Weight: 28%
Domain: Medicine & Life Sciences
Interleukin-15
Concept: Interleukin-15
Weight: 27%
Domain: Medicine & Life Sciences
Research OutputsResearch Output authored by Xian Chang Li is tagged with the concept

Journals

Journal of Immunology

ISSNs: 0022-1767

Additional searchable ISSN (Electronic): 1550-6606

Journal

27

Transplantation

ISSNs: 0041-1337

Lippincott Williams and Wilkins

Journal

17

American Journal of Transplantation

ISSNs: 1600-6135

Additional searchable ISSN (Electronic): 1600-6143

Wiley

Journal

15

Transplantation proceedings

ISSNs: 0041-1345

Elsevier

Journal

10

Current Opinion in Organ Transplantation

ISSNs: 1087-2418

Additional searchable ISSN (Electronic): 1531-7013

Lippincott Williams and Wilkins

Journal

8
has published Research OutputsResearch Output by Xian Chang Li

Research Network

Visualization: Institutional Network

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Xian Chang Li

Visualization: Co-author Network

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Xian Chang Li

Shared Pub. Internal Organizations

Houston Methodist Hospital

Organizational unit: Schools & Hospitals

27

Lynda K. and David M. Underwood Center for Digestive Disorders

Organizational unit: Centers of Excellence

4

Department of Medicine

Organizational unit: Departments

4

Department of Nanomedicine

Organizational unit: Departments

3

Center for Cardiovascular Regeneration

Organizational unit: Programs

3
has Research OutputsResearch Output by Xian Chang Li

Shared Pub. External Organizations

Harvard University

External organization: Academic

37

Harvard Medical School

External organization: Unknown

29

Central South University

External organization: Academic

14

Brigham and Women's Hospital

External organization: Unknown

13

London Health Sciences Centre

External organization: Unknown

12
has Research OutputsResearch Output by Xian Chang Li

Shared Pub. Internal co-authors

has co-authored Research OutputsResearch Output with Xian Chang Li

Shared Pub. External co-authors

Terry B. Strom

External person

31

Gulcin Demirci

External person

21

X. X. Zheng

External person

17

Y. Li

External person

15

David Grant

External person

14
has co-authored Research OutputsResearch Output with Xian Chang Li

ID: 2282297