Research output per year
Research output per year
Personal profile
Personal profile
Dr. Wenhao Chen earned his Ph.D. in Biomedical Science from the University of Toronto in 2006. He held faculty appointments at the University of Toledo College of Medicine in Toledo, Ohio and Baylor College of Medicine in Houston, Texas before becoming a member of Houston Methodist Research Institute in 2013. As a member of the Transplantation Immunology Program, Dr. Chen studies the cellular and molecular mechanisms underlying immune tolerance. He has published more than 40 original papers and review articles in high-impact scientific journals.
Research interests
Dr. Chen’s research interests are to define the molecular mechanisms by which immune cells reject the transplanted organs or cause autoimmune type 1 diabetes and develop novel strategies to selectively abrogate undesired immune responses against self-islets or transplanted organs.
Education/Academic qualification
Immunology, Postdoctoral Associate, Baylor College of Medicine
Transplantation Immunology, Postdoctoral Fellowship, University of Texas Health Science Center at Houston
Immunology, Postdoctoral Fellowship, University of Toronto
Biomedical Science, PhD, University of Toronto
Divisions
- Abdominal Transplant
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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CD8+ T cell differentiation into NK-like effector cells drives transplant rejection
Zou, D., Yi, S. G., Dai, Y., Truong, L., Gaber, L. W., Knight, R. J., Xiao, X., Ghobrial, R. M., Li, X. C., Zhao, Z., Chen, W. & Gaber, A. O., Jan 21 2026, (E-pub ahead of print) In: Molecular Therapy. 34, 5, p. 2709-2724 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Beyond T-cell subsets: stemness and adaptation redefining immunity and immunotherapy
Zou, D., Li, X. C. & Chen, W., Sep 2025, In: Cellular and Molecular Immunology. 22, 9, p. 957-974 18 p.Research output: Contribution to journal › Review article › peer-review
18 Link opens in a new tab Scopus citations -
Epigenetically modulating macrophage subpopulations to promote long-term allograft survival in a mouse heart transplant model
Su, X., Deng, G., Sun, S., Wang, G., Hennessy-Strahs, S., Li, J., Wen, M., Mao, Z., Ghobrial, R. M., Xiao, X., Chen, W. & Li, X. C., Oct 2025, In: American Journal of Transplantation. 25, 10, p. 2067-2081 15 p.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Scopus citations -
IRF4 expression by NK precursors predetermines exhaustion of NK cells during tumor metastasis
Zhang, X., Yin, Z., Wu, J., Xiang, X., Zou, D., Wang, G., Fu, J., Lan, P., Minze, L. J., Li, X. C. & Chen, W., Jul 2025, In: Nature immunology. 26, 7, p. 1062-1073 12 p.Research output: Contribution to journal › Article › peer-review
7 Link opens in a new tab Scopus citations -
Transient Anti-TCRβ mAb Treatment Induces CD4+ T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus
Gonzalez, N. M., Zou, D., Zeng, Z., Feng, F. X., Zhang, X., Sannes, C., Gu, A., Zu, Y. & Chen, W., Feb 2025, In: Immunology. 174, 2, p. 239-246 8 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations
Prizes
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Presidential Award - Peer Reviewed Publication
Chen, W. (Recipient), 2023
Prize: Prize (including medals and awards)
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Presidential Award - Peer Reviewed Publication
Chen, W. (Recipient), Oct 14 2025
Prize: Prize (including medals and awards)