Projects per year
Personal profile
Personal profile
Dr. Cristini is a leading expert and researcher in the fields of mathematical and computational biology, applied and computational mathematics, physical oncology, complex fluids and microfluidics, multidisciplinary (bio)materials science, and systems biology and medicine.
He was included in the 2014 ISI Highly-Cited Researchers in Mathematics, a total of less than one hundred mathematicians worldwide named “most influential scientific minds.” He served as editor for Cancer Research and several biomedical journals including NeuroImage and PloS Computational Biology. He has published two book monographs with Cambridge University Press in 2010 and with CRC Press in 2017, and over 90 peer-reviewed journal articles.
Dr. Cristini was the first recipient of the “Andreas Acrivos Dissertation Award in Fluid Dynamics” by the American Physical Society in 2000. His 2005 paper in the Bulletin of Mathematical Biology was in the top 0.1% of citations in the field of Mathematics and has been designated as a “New Hot Paper in the field of Mathematics” by the Institute for Scientific Information (ISI) Web of Knowledge; two articles have been featured in the Cancer Research Highlights of the American Association for Cancer Research. His research has been highly recognized internationally and by the media and several science museums in the US, and has been supported by the Cullen Trust for Health Care, the National Science Foundation, the National Institutes of Health, the Department of Defense, the States of California, Texas and New Mexico among the others.
For more than 15 years, Dr. Cristini has continually served in PI roles on several NSF, NIH, and DoD grants focused on the development of predictive multi-scale patient-specific computational models of tumor growth and mechanistic mathematical models of tumor response to chemo/immunotherapy, targeted therapy, and nano-therapeutics, most notably as part of multinstitutional grants including two NSF and joint NSF/NIGMS grants (funded in September 2017 and 2013, respectively), two R01s beginning in April and July 2018, two U01 NCI grants on pancreatic and gynecological cancers (funded in August 2015 and July 2017, respectively), two NCI Physical Sciences in Oncology Centers (PS-OC), one NCI Center for Excellence in Cancer Nanotechnology (CCNE), of which he served as the overall PI in 2015-2016, one NCI Integrative Cancer Biology Program (ICBP) center grant, and one NIGMS P50 grant in systems biology.
Dr. Cristini has developed and taught novel courses in Computational and Precision Biomedicine, and has mentored and trained graduate students, postdocs, and junior faculty, including the NIGMS Spatio-Temporal Modeling Center (STMC UNM) and the NIGMS-IRACDA Academic Science Education and Research Training (ASERT) program mentees.
Free-text keywords
- Mathematical modeling
Research Area Keywords
- Cancer
- Nanomedicine
- Neurosciences
- Immunobiology & Inflammation
- Systems Medicine & Bioinformatics
- Precision Medicine
- Regenerative Medicine
- Clinical Translation & Trials
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Network
Projects
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The University of Texas M.D. Anderson Cancer Center SPORE in Hepatocellular Carcinoma
9/1/20 → 8/31/24
Project: Federal Funding Agencies
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Imaging and Molecular correlates of progression in cystic neoplasms of the pancreas
9/1/18 → 8/31/21
Project: Federal Funding Agencies
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miR-155 targeted therapeutics for precision medicine in lung cancer
8/3/18 → 7/31/23
Project: Federal Funding Agencies
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A Targeted Nanomedicine Prototype Against Enzalutamide-resistant Prostate Cancer
8/1/18 → 7/31/23
Project: Federal Funding Agencies
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Targeted Therapeutics for ovarian cancer and its microenvironment treatment and theoretical modeling
6/1/18 → 5/31/22
Project: Federal Funding Agencies
Research Output
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A mathematical model to predict nanomedicine pharmacokinetics and tumor delivery
Dogra, P., Butner, J. D., Ruiz Ramírez, J., Chuang, Y. L., Noureddine, A., Jeffrey Brinker, C., Cristini, V. & Wang, Z., 2020, In : Computational and Structural Biotechnology Journal. 18, p. 518-531 14 p.Research output: Contribution to journal › Article
4 Scopus citations -
A mechanistic immunotherapy model provides patient-specific quantification of immune response and associated long-term tumor burden
Butner, J., Wang, Z., Elganainy, D., Plodinec, M., Calin, G. A., Dogra, P., Nizzero, S., Ruiz Ramírez, J., Chung, C., Koay, E. J., Welsh, J., Hong, D. S. & Cristini, V., Dec 2020, (Accepted/In press) In : Nature Biomedical Engineering.Research output: Contribution to journal › Article
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Graph theory in the study of Alzheimer’s disease progression
Pelaez, M., Dogra, P., Wang, Z. & Cristini, V., Mar 10 2020, Open Access Government.Research output: Book/Report › Other report
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Image-guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies
Dogra, P., Butner, J. D., Nizzero, S., Ruiz Ramírez, J., Noureddine, A., Peláez, M. J., Elganainy, D., Yang, Z., Le, A. D., Goel, S., Leong, H. S., Koay, E. J., Brinker, C. J., Cristini, V. & Wang, Z., Sep 1 2020, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 12, 5, e1628.Research output: Contribution to journal › Review article
1 Scopus citations -
Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection
Zaid, M., Elganainy, D., Dogra, P., Dai, A., Widmann, L., Fernandes, P., Wang, Z., Pelaez, M. J., Ramirez, J. R., Singhi, A. D., Dasyam, A. K., Brand, R. E., Park, W. G., Rahmanuddin, S., Rosenthal, M. H., Wolpin, B. M., Khalaf, N., Goel, A., Von Hoff, D. D., Tamm, E. P. & 3 others, , Dec 2 2020, In : Frontiers in Oncology. 10, 596931.Research output: Contribution to journal › Article
Open Access
Prizes
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Award for Excellence in Peer-Reviewed Publication
Cristini, Vittorio (Recipient) & Wang, Zhihui (Recipient), Oct 31 2018
Prize: Prize (including medals and awards)