Research outputs

  1. 2020
  2. Limitations of cell-lineage-specific non-dynamic gene recombination in CD11c.Cre+ITGA4fl/fl mice

    Manouchehri, N., Hussain, R. Z., Cravens, P. D., Doelger, R., Greenberg, B. M., Okuda, D. T., Forsthuber, T. G., Eagar, T. N. & Stüve, O., Jul 15 2020, In : Journal of Neuroimmunology. 344, 577245.

    Research output: Contribution to journalArticle

  3. 2019
  4. α4-integrin deficiency in B cells does not affect disease in a T-cell-mediated EAE disease model

    Hussain, R. Z., Cravens, P. D., Miller-Little, W. A., Doelger, R., Granados, V., Herndon, E., Okuda, D. T., Eagar, T. N. & Stüve, O., Jul 1 2019, In : Neurology: Neuroimmunology and NeuroInflammation. 6, 4, e563.

    Research output: Contribution to journalArticle

  5. 2018
  6. Presenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitis

    Cummings, M., Arumanayagam, A. C. S., Zhao, P., Kannanganat, S., Stuve, O., Karandikar, N. J. & Eagar, T. N., Aug 1 2018, In : PloS one. 13, 8, e0200752.

    Research output: Contribution to journalArticle

  7. 2017
  8. The detrimental impact of persistent vs an isolated occurrence of de novo donor-specific antibodies on intermediate-term renal transplant outcomes

    Loucks-DeVos, J. M., Eagar, T. N., Gaber, A. O., Patel, S. J., Teeter, L. D., Graviss, E. A. & Knight, R. J., Aug 2017, In : Clinical Transplantation. 31, 8, e13025.

    Research output: Contribution to journalArticle

  9. Early clearance vs persistence of de novo donor-specific antibodies following lung transplantation

    Islam, A. K., Sinha, N., DeVos, J. M., Kaleekal, T. S., Jyothula, S. S., Teeter, L. D., Nguyen, D. T. M., Eagar, T. N., Moore, L. W., Puppala, M., Wong, S. T. C., Knight, R. J., Frost, A. E., Graviss, E. A. & Osama Gaber, A., Jun 28 2017, In : Clinical Transplantation.

    Research output: Contribution to journalArticle

  10. 2016
  11. A single amino acid substitution prevents recognition of a dominant human aquaporin-4 determinant in the context of HLA-DRB1-03:01 by a murine TCR

    Arellano, B., Hussain, R., Miller-Little, W. A., Herndon, E., Lambracht-Washington, D., Eagar, T. N., Lewis, R., Healey, D., Vernino, S., Greenberg, B. M. & Stüve, O., Apr 1 2016, In : PloS one. 11, 4, e0152720.

    Research output: Contribution to journalArticle

  12. 2015
  13. T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

    Raphael, I., Nalawade, S., Eagar, T. N. & Forsthuber, T. G., Jul 1 2015, In : Cytokine. 74, 1, p. 5-17 13 p.

    Research output: Contribution to journalArticle

  14. 2014
  15. Immune surveillance of the central nervous system in multiple sclerosis - Relevance for therapy and experimental models

    Hussain, R. Z., Hayardeny, L., Cravens, P. C., Yarovinsky, F., Eagar, T. N., Arellano, B., Deason, K., Castro-Rojas, C. & Stüve, O., Nov 15 2014, In : Journal of Neuroimmunology. 276, 1-2, p. 9-17 9 p.

    Research output: Contribution to journalArticle

  16. Testing effects of glatiramer acetate and fingolimod in an infectious model of CNS immune surveillance

    Castro-Rojas, C., Deason, K., Hussain, R. Z., Hayardeny, L., Cravens, P. C., Yarovinsky, F., Eagar, T. N., Arellano, B. & Stüve, O., Nov 15 2014, In : Journal of Neuroimmunology. 276, 1-2, p. 232-235 4 p.

    Research output: Contribution to journalArticle

  17. 2013
  18. A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease

    Lambracht-Washington, D., Qu, B. X., Fu, M., Anderson, L. D., Eagar, T. N., Stüve, O. & Rosenberg, R. N., Jan 15 2013, In : Journal of Neuroimmunology. 254, 1-2, p. 63-68 6 p.

    Research output: Contribution to journalArticle

  19. 2012
  20. Parkinson's disease: A role for the immune system

    German, D. C., Eagar, T. N. & Sonsalla, P. K., Dec 1 2012, In : Current Molecular Pharmacology. 5, 3, p. 340-349 10 p.

    Research output: Contribution to journalReview article

  21. 2011
  22. Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet

    Cravens, P. D., Hussain, R. Z., Zacharias, T. E., Ben, L. H., Herndon, E., Vinnakota, R., Lambracht-Washington, D., Nessler, S., Zamvil, S. S., Eagar, T. N. & Stüve, O., Jun 24 2011, In : Journal of Neuroinflammation. 8, 73.

    Research output: Contribution to journalArticle

  23. Rituximab therapy reduces organ-specific T cell responses and ameliorates experimental autoimmune encephalomyelitis

    Monson, N. L., Cravens, P., Hussain, R., Harp, C. T., Cummings, M., Martin, M. D. P., Ben, L. H., Do, J., Lyons, J. A., Lovette-Racke, A., Cross, A. H., Racke, M. K., Stüve, O., Shlomchik, M. & Eagar, T. N., Feb 28 2011, In : PloS one. 6, 2, e17103.

    Research output: Contribution to journalArticle

  24. DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation.

    Lambracht-Washington, D., Qu, B. X., Fu, M., Anderson, L. D., Stüve, O., Eagar, T. N. & Rosenberg, R. N., 2011, In : Cellular and Molecular Neurobiology. 31, 6, p. 867-874 8 p.

    Research output: Contribution to journalArticle

  25. 2010
  26. Translational research in neurology and neuroscience 2010: Multiple sclerosis

    Stüve, O., Kieseier, B. C., Hemmer, B., Hartung, H. P., Awad, A., Frohman, E. M., Greenberg, B. M., Racke, M. K., Zamvil, S. S., Phillips, J. T., Gold, R., Chan, A., Zettl, U., Milo, R., Marder, E., Khan, O. & Eagar, T. N., Nov 1 2010, In : Archives of neurology. 67, 11, p. 1307-1315 9 p.

    Research output: Contribution to journalReview article

  27. Memory B cells from a subset of treatment-naïve relapsing-remitting multiple sclerosis patients elicit CD4+ T-cell proliferation and IFN-γ production in response to myelin basic protein and myelin oligodendrocyte glycoprotein

    Harp, C. T., Ireland, S., Davis, L. S., Remington, G., Cassidy, B., Cravens, P. D., Stuve, O., Lovett-Racke, A. E., Eagar, T. N., Greenberg, B. M., Racke, M. K., Cowell, L. G., Karandikar, N. J., Frohman, E. M. & Monson, N. L., Oct 1 2010, In : European Journal of Immunology. 40, 10, p. 2942-2956 15 p.

    Research output: Contribution to journalArticle

  28. Analysis of three plasmid systems for use in DNA Aβ42 immunization as therapy for Alzheimer's disease

    Qu, B. X., Lambracht-Washington, D., Fu, M., Eagar, T. N., Stüve, O. & Rosenberg, R. N., Jul 1 2010, In : Vaccine. 28, 32, p. 5280-5287 8 p.

    Research output: Contribution to journalArticle

  29. Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling

    Hu, W., Nessler, S., Hemmer, B., Eagar, T. N., Kane, L. P., Leliveld, S. R., Müller-Schiffmann, A., Gocke, A. R., Lovett-Racke, A., Ben, L. H., Hussain, R. Z., Breil, A., Elliott, J. L., Puttaparthi, K., Cravens, P. D., Singh, M. P., Petsch, B., Stitz, L., Racke, M. K., Korth, C. & 1 othersStüve, O., Feb 1 2010, In : Brain. 133, 2, p. 375-388 14 p.

    Research output: Contribution to journalArticle

  30. Reversible alopecia associated with glatiramer acetate

    Pacheco, M. F., Jacobe, H., Eagar, T. N. & Stüve, O., Jan 1 2010, In : Archives of neurology. 67, 9, 1 p.

    Research output: Contribution to journalLetter

  31. 2009
  32. DNA β-amyloid1-42 trimer immunization for alzheimer diseaseina wild-type mouse model

    Lambracht-Washington, D., Qu, B. X., Fu, M., Eagar, T. N., Stüve, O. & Rosenberg, R. N., Dec 16 2009, In : JAMA - Journal of the American Medical Association. 302, 16, p. 1796-1802 7 p.

    Research output: Contribution to journalArticle

  33. Direct and consensual murine pupillary reflex metrics: Establishing normative values

    Hussain, R. Z., Hopkins, S. C., Frohman, E. M., Eagar, T. N., Cravens, P. C., Greenberg, B. M., Vernino, S. & Stüve, O., Dec 3 2009, In : Autonomic Neuroscience: Basic and Clinical. 151, 2, p. 164-167 4 p.

    Research output: Contribution to journalArticle

  34. Depletion of B lymphocytes from cerebral perivascular spaces by rituximab

    Martin, M. D. P., Cravens, P. D., Winger, R., Kieseier, B. C., Cepok, S., Eagar, T. N., Zamvil, S. S., Weber, M. S., Frohman, E. M., Kleinschmidt-DeMasters, B. K., Montine, T. J., Hemmer, B., Marra, C. M. & Stüve, O., Aug 1 2009, In : Archives of neurology. 66, 8, p. 1016-1020 5 p.

    Research output: Contribution to journalArticle

  35. 200 years after darwin

    Rosenberg, R. N., Stüve, O. & Eagar, T. N., Feb 11 2009, In : JAMA - Journal of the American Medical Association. 301, 6, p. 660-662 3 p.

    Research output: Contribution to journalComment/debate

  36. 200 years after darwin

    Rosenberg, R. N., Stüve, O. & Eagar, T. N., Feb 1 2009, In : Archives of neurology. 66, 2, p. 153-155 3 p.

    Research output: Contribution to journalEditorial

  37. Genetic polymorphism at codon 129 of the prion protein gene is not associated with multiple sclerosis

    Stüve, O., Korth, C., Gabatto, P., Cameron, E. M., Hu, W., Eagar, T. N., Monson, N. L., Frohman, E. M., Racke, M. K., Zabetian, C. P. & Oksenberg, J. R., Feb 1 2009, In : Archives of neurology. 66, 2, p. 280-281 2 p.

    Research output: Contribution to journalArticle

  38. Quinpramine is a novel compound effective in ameliorating brain autoimmune disease

    Singh, M. P., Hörste, G. M. Z., Hu, W., Mausberg, A. K., Cravens, P. D., Eagar, T. N., Löber, S., Klingenstein, R., Gmeiner, P., Korth, C., Kieseier, B. C. & Stüve, O., Feb 1 2009, In : Experimental Neurology. 215, 2, p. 397-400 4 p.

    Research output: Contribution to journalArticle

  39. PEG minocycline-liposomes ameliorate CNS autoimmune disease

    Hu, W., Metselaar, J., Ben, L. H., Cravens, P. D., Singh, M. P., Frohman, E. M., Eagar, T. N., Racke, M. K., Kieseier, B. C. & Stüve, O., Jan 7 2009, In : PloS one. 4, 1, e4151.

    Research output: Contribution to journalArticle

  40. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

    Fife, B. T., Pauken, K. E., Eagar, T. N., Obu, T., Wu, J., Tang, Q., Azuma, M., Krummel, M. F. & Bluestone, J. A., Jan 1 2009, In : Nature immunology. 10, 11, p. 1185-1192 8 p.

    Research output: Contribution to journalArticle

  41. 2008
  42. Decrease in the numbers of dendritic cells and CD4 + T cells in cerebral perivascular spaces due to natalizumab

    Del Pilar Martin, M., Cravens, P. D., Winger, R., Frohman, E. M., Racke, M. K., Eagar, T. N., Zamvil, S. S., Weber, M. S., Hemmer, B., Karandikar, N. J., Kleinschmidt-DeMasters, B. K. & Stüve, O., Dec 1 2008, In : Archives of neurology. 65, 12, p. 1596-1603 8 p.

    Research output: Contribution to journalArticle

  43. Immunologic Mechanisms of Multiple Sclerosis

    Frohman, E. M., Eagar, T. N., Monson, N., Stuve, O. & Karandikar, N., Nov 1 2008, In : Neuroimaging Clinics of North America. 18, 4, p. 577-588 12 p.

    Research output: Contribution to journalReview article

  44. B cells, antibodies, and tertiary lymphoid tissue in MS brains

    Stüve, O. & Eagar, T. N., Sep 1 2008, In : The Lancet Neurology. 7, 9, p. 766-767 2 p.

    Research output: Contribution to journalLetter

  45. DNA-based vaccines: The future of multiple sclerosis therapy?

    Stüve, O., Cravens, P. D. & Eagar, T. N., Mar 1 2008, In : Expert Review of Neurotherapeutics. 8, 3, p. 351-360 10 p.

    Research output: Contribution to journalReview article

  46. Prion proteins: Physiological functions and role in neurological disorders

    Hu, W., Kieseier, B., Frohman, E., Eagar, T. N., Rosenberg, R. N., Hartung, H. P. & Stüve, O., Jan 15 2008, In : Journal of the Neurological Sciences. 264, 1-2, p. 1-8 8 p.

    Research output: Contribution to journalReview article

  47. 2007
  48. DNA plasmid vaccination for multiple sclerosis

    Stüve, O., Eagar, T. N., Frohman, E. M. & Cravens, P. D., Oct 1 2007, In : Archives of neurology. 64, 10, p. 1385-1386 2 p.

    Research output: Contribution to journalEditorial

  49. 2006
  50. Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway

    Fife, B. T., Guleria, I., Bupp, M. G., Eagar, T. N., Tang, Q., Bour-Jordan, H., Yagita, H., Azuma, M., Sayegh, M. H. & Bluestone, J. A., Nov 1 2006, In : Journal of Experimental Medicine. 203, 12, p. 2737-2747 11 p.

    Research output: Contribution to journalArticle

  51. 2005
  52. Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis

    Smith, C. E., Eagar, T. N., Strominger, J. L. & Miller, S. D., Jul 5 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 27, p. 9595-9600 6 p.

    Research output: Contribution to journalArticle

  53. 2004
  54. CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance

    Eagar, T. N., Turley, D. M., Padilla, J., Karandikar, N. J., Tan, L., Bluestone, J. A. & Miller, S. D., Jun 15 2004, In : Journal of Immunology. 172, 12, p. 7442-7450 9 p.

    Research output: Contribution to journalArticle

  55. Notch 1 signaling regulates peripheral T cell activation

    Eagar, T. N., Tang, Q., Wolfe, M., He, Y., Pear, W. S. & Bluestone, J. A., Apr 1 2004, In : Immunity. 20, 4, p. 407-415 9 p.

    Research output: Contribution to journalArticle

  56. 2002
  57. Functional activation of myelin-specific T cells by virus-induced molecular mimicry

    Olson, J. K., Eagar, T. N. & Miller, S. D., Sep 1 2002, In : Journal of Immunology. 169, 5, p. 2719-2726 8 p.

    Research output: Contribution to journalArticle

  58. The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance

    Eagar, T. N., Karandikar, N. J., Bluestone, J. A. & Miller, S. D., May 4 2002, In : European Journal of Immunology. 32, 4, p. 972-981 10 p.

    Research output: Contribution to journalArticle

  59. 2001
  60. Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis

    Theien, B. E., Vanderlugt, C. L., Eagar, T. N., Nickerson-Nutter, C., Nazareno, R., Kuchroo, V. K. & Miller, S. D., Jan 1 2001, In : Journal of Clinical Investigation. 107, 8, p. 995-1006 12 p.

    Research output: Contribution to journalArticle

  61. Functional role of epitope spreading in the chronic pathogenesis of autoimmune and virus-induced demyelinating diseases

    Miller, S. D. & Eagar, T. N., Jan 1 2001, In : Advances in experimental medicine and biology. 490, p. 99-107 9 p.

    Research output: Contribution to journalArticle

  62. 2000
  63. CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis

    Karandikar, N. J., Eagar, T. N., Vanderlugt, C. L., Bluestone, J. A. & Miller, S. D., Sep 22 2000, In : Journal of Neuroimmunology. 109, 2, p. 173-180 8 p.

    Research output: Contribution to journalArticle

  64. Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis

    Vanderlugt, C. L., Neville, K. L., Nikcevich, K. M., Eagar, T. N., Bluestone, J. A. & Miller, S. D., Jan 15 2000, In : Journal of Immunology. 164, 2, p. 670-678 9 p.

    Research output: Contribution to journalArticle

  65. 1998
  66. The functional significance of epitope spreading and its regulation by co-stimulatory molecules

    Vanderlugt, C. L., Begolka, W. S., Neville, K. L., Katz-Levy, Y., Howard, L. M., Eagar, T. N., Bluestone, J. A. & Miller, S. D., Aug 1 1998, In : Immunological Reviews. 164, p. 63-72 10 p.

    Research output: Contribution to journalArticle

  67. Tissue-specific up-regulation of B7-1 expression and function during the course of murine relapsing experimental autoimmune encephalomyelitis

    Karandikar, N. J., Vanderlugt, C. L., Eagar, T. N., Tan, L., Bluestone, J. A. & Miller, S. D., Jul 1 1998, In : Journal of Immunology. 161, 1, p. 192-199 8 p.

    Research output: Contribution to journalArticle

  68. Activation of antigen-specific T cells in vivo induced by tolerogenic encounter with antigen-coupled splenocytes

    Eagar, T. N., Tan, L. J., Leg, H., Barrett, T. & Miller, S. D., Mar 20 1998, In : FASEB Journal. 12, 5

    Research output: Contribution to journalArticle

ID: 12616794