Projects per year
Personal profile
Personal profile
Dr. Eagar received his PhD in immunology and molecular pathogenesis from the Northwestern University Medical School in Chicago in 2001. He then completed an immunology fellowship at the University of California at San Francisco and an HLA fellowship at Houston Methodist Hospital. Dr. Eagar was an assistant professor in the Department of Pathology and Immunology at The University of Texas Southwestern Medical Center in Dallas before joining the Department of Pathology and Genomic Medicine here in 2013.
Research interests
Dr. Eagar is board certified in histocompatibility by the American Board of Histocompatibility and Immunogenetics. His research interests include identifying immune processes involved in the pathogenesis of multiple sclerosis and transplant rejection, with a focus on finding novel regulatory pathways involved in T cell activation that might be harnessed for therapeutic intervention.
Research Area Keywords
- Infectious Disease & Pathology
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Projects
- 2 Finished
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Defining Immunology Frailty as a Predictor of Human Liver Allograft Recipient Futility
Chen, W., Eagar, T. N., Ghobrial, R. M., Graviss, E. A., Gupte, A. A., Hamilton, D. J. & Li, X. C.
4/10/19 → 8/31/19
Project: Federal Funding Agencies
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Modulating B and T cell functions in EAE through gamma secretase and Notch
Natl Inst of Neuro Disorders and Stroke
8/1/13 → 5/31/18
Project: Federal Funding Agencies
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Early humoral immune response to two doses of severe acute respiratory syndrome coronavirus 2 vaccine in a diverse group of solid organ transplant candidates and recipients
Huang, H. J., Yi, S. G., Mobley, C. M., Saharia, A., Bhimaraj, A., Moore, L. W., Kloc, M., Adrogue, H. E., Graviss, E. A., Nguyen, D. T., Eagar, T. N., Jones, S. L., Ankoma-Sey, V., MacGillivray, T. E., Knight, R. J., Gaber, A. O. & Ghobrial, R. M., May 2022, In: Clinical Transplantation. 36, 5, e14600.Research output: Contribution to journal › Article › peer-review
Open Access -
Early humoral immune response to two doses of severe acute respiratory syndrome coronavirus 2 vaccine in a diverse group of solid organ transplant candidates and recipients
Huang, H. J., Yi, S. G., Mobley, C. M., Saharia, A., Bhimaraj, A., Moore, L. W., Kloc, M., Adrogue, H. E., Graviss, E. A., Nguyen, D. T., Eagar, T. N., Jones, S. L., Ankoma-Sey, V., MacGillivray, T. E., Knight, R. J., Gaber, A. O. & Ghobrial, R. M., Jan 26 2022, (E-pub ahead of print) In: Clinical Transplantation. p. e14600Research output: Contribution to journal › Article › peer-review
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CD11c+CD88+CD317+ myeloid cells are critical mediators of persistent CNS autoimmunity
Manouchehri, N., Hussain, R. Z., Cravens, P. D., Esaulova, E., Artyomov, M. N., Edelson, B. T., Wu, G. F., Cross, A. H., Doelger, R., Loof, N., Eagar, T. N., Forsthuber, T. G., Calvier, L., Herz, J. & Stüve, O., Apr 6 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 14, e2014492118.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
Gontu, A., Srinivasan, S., Salazar, E., Nair, M. S., Nissly, R. H., Greenawalt, D., Bird, I. M., Herzog, C. M., Ferrari, M. J., Poojary, I., Katani, R., Lindner, S. E., Minns, A. M., Rossi, R., Christensen, P. A., Castillo, B., Chen, J., Eagar, T. N., Yi, X., Zhao, P. & 7 others, , Feb 24 2021, In: Communications Biology. 4, 1, 267.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Long-Term Follow-Up of Renal Transplant Recipients Treated With IVIG for De Novo Donor-Specific Antibodies
Knight, R. J., Loucks-Devos, J., Khan, N. A., Nguyen, D. T., Graviss, E. A., Eagar, T. N., Patel, S. J. & Osama Gaber, A., Jul 1 2021, In: Transplantation Proceedings. 53, 6, p. 1865-1871 7 p.Research output: Contribution to journal › Article › peer-review