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Todd N. Eagar, PhD

Former affiliation
  • 2630 Citations
  • 23 h-Index
19982020

Research output per year

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Personal profile

Personal profile

Dr. Eagar received his PhD in immunology and molecular pathogenesis from the Northwestern University Medical School in Chicago in 2001. He then completed an immunology fellowship at the University of California at San Francisco and an HLA fellowship at Houston Methodist Hospital. Dr. Eagar was an assistant professor in the Department of Pathology and Immunology at The University of Texas Southwestern Medical Center in Dallas before joining the Department of Pathology and Genomic Medicine here in 2013.

Research interests

Dr. Eagar is board certified in histocompatibility by the American Board of Histocompatibility and Immunogenetics. His research interests include identifying immune processes involved in the pathogenesis of multiple sclerosis and transplant rejection, with a focus on finding novel regulatory pathways involved in T cell activation that might be harnessed for therapeutic intervention.

Research Area Keywords

  • Infectious Disease & Pathology

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Projects

Defining Immunology Frailty as a Predictor of Human Liver Allograft Recipient Futility

Lunsford, K. E., Chen, W., Eagar, T. N., Ghobrial, R. M., Graviss, E. A., Gupte, A. A., Hamilton, D. J. & Li, X. C.

4/10/19 → 8/31/19

Project: Federal Funding Agencies

Modulating B and T cell functions in EAE through gamma secretase and Notch

Eagar, T. N.

Natl Inst of Neuro Disorders and Stroke

8/1/13 → 5/31/18

Project: Federal Funding Agencies

Research Output

Convalescent plasma anti-SARS-CoV-2 spike protein ectodomain and receptor binding domain IgG correlate with virus neutralization

Salazar, E., Kuchipudi, S. V., Christensen, P. A., Eagar, T., Yi, X., Zhao, P., Jin, Z., Long, S. W., Olsen, R. J., Chen, J., Castillo, B., Leveque, C., Towers, D., Lavinder, J. J., Gollihar, J., Cardona, J. A., Ippolito, G. C., Nissly, R. H., Bird, I., Greenawalt, D. & 14 others, Rossi, R. M., Gontu, A., Srinivasan, S., Poojary, I., Cattadori, I. M., Hudson, P., Josleyn, N. M., Prugar, L., Huie, K. E., Herbert, A. S., Bernard, D. W., Dye, J. M., Kapur, V. & Musser, J. M., Sep 10 2020, In : The Journal of clinical investigation.

Research output: Contribution to journal › Article

    • Limitations of cell-lineage-specific non-dynamic gene recombination in CD11c.Cre+ITGA4fl/fl mice

    Manouchehri, N., Hussain, R. Z., Cravens, P. D., Doelger, R., Greenberg, B. M., Okuda, D. T., Forsthuber, T. G., Eagar, T. N. & Stüve, O., Jul 15 2020, In : Journal of Neuroimmunology. 344, 577245.

    Research output: Contribution to journal › Article

    • Treatment of Coronavirus Disease 2019 (COVID-19) Patients with Convalescent Plasma

    Salazar, E., Perez, K. K., Ashraf, M., Chen, J., Castillo, B., Christensen, P. A., Eubank, T., Bernard, D. W., Eagar, T. N., Long, S. W., Subedi, S., Olsen, R. J., Leveque, C., Schwartz, M. R., Dey, M., Chavez-East, C., Rogers, J., Shehabeldin, A., Joseph, D., Williams, G. & 15 others, Thomas, K., Masud, F., Talley, C., Dlouhy, K. G., Lopez, B. V., Hampton, C., Lavinder, J., Gollihar, J. D., Maranhao, A. C., Ippolito, G. C., Saavedra, M. O., Cantu, C. C., Yerramilli, P., Pruitt, L. & Musser, J. M., Aug 2020, In : American Journal of Pathology. 190, 8, p. 1680-1690 11 p.

    Research output: Contribution to journal › Article

    Open Access

    • α4-integrin deficiency in B cells does not affect disease in a T-cell-mediated EAE disease model

    Hussain, R. Z., Cravens, P. D., Miller-Little, W. A., Doelger, R., Granados, V., Herndon, E., Okuda, D. T., Eagar, T. N. & Stüve, O., Jul 1 2019, In : Neurology: Neuroimmunology and NeuroInflammation. 6, 4, e563.

    Research output: Contribution to journal › Article

    • Presenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitis

    Cummings, M., Arumanayagam, A. C. S., Zhao, P., Kannanganat, S., Stuve, O., Karandikar, N. J. & Eagar, T. N., Aug 2018, In : PLoS ONE. 13, 8, e0200752.

    Research output: Contribution to journal › Article