Personal profile
Personal profile
Dr. Shen is a general surgical pathologist with interest in genitourinary (GU) pathology. After completing his residency training in Anatomical and Clinical Pathology and fellowship training in Surgical Pathology, Dr. Shen became an Assistant Professor at Baylor College of Medicine before joining the Department of Pathology and Genomic Medicine at Houston Methodist Hospital in 2004. In 2005, he joined the Weill Medical College faculty and is a Full Member of the Research Institute.
Dr. Shen is a general surgical pathologist with strong subspecialty expertise in GU cancers. He is currently the Director of Surgical Pathology and Fellowship Director of GU and Medical Kidney Pathology at the Houston Methodist Hospital. He has published more than 150 articles, primarily in GU pathology. He has been a co-editor of three textbooks, authored several chapters in GU pathology, and was a contributing author for the 2016 WHO Classification of Tumors of the Urinary System and Male Genital Organs. Dr. Shen serves as a Section Editor for Archives of Pathology & Laboratory Medicine and an ad hoc reviewer for several pathology and urology journals. He is currently a member of both the Surgical Pathology Committee of College of American Pathologist (CAP) and the Education Committee of United States Canadian Academy of Pathology (USCAP). Dr. Shen has been teaching urologic pathology for trainees in pathology and urology for over 23 years, and has been recognized nationally and internationally as a consultant and invited speaker.
Research interests
Dr. Shen’s research involves identifying morphologic and molecular neoplasm abnormalities and correlating these with diagnosis, prognosis, and in some instances, future treatment. He is involved in independent and collaborative studies using conventional histomorphologic techniques, immunohistochemical methods, tissue microarray, and new molecular methods to study cancers of the kidney, urinary bladder, prostate, and testis.
Education/Academic qualification
Surgical Pathology, Clinical Fellowship, University of Texas MD Anderson Cancer Center
Jul 1 2001 → Jun 30 2002
Award Date: Jun 30 2002
Residency, Penn State Milton S. Hershey Medical Center
Jul 1 1997 → Jun 30 2001
Award Date: Jun 30 2001
MD, Tongji Medical College, Huazhong University of Science and Technology
Sep 1 1979 → Jul 1 1987
Award Date: Jul 1 1987
Research Fellowship, National Institutes of Health
1995 → 1997
Biochemistry & Molecular Biology, Postdoctoral Fellowship, University of Texas Health Science Center at Houston
1994 → 1995
Biochemistry & Molecular Biology, PhD, University of Texas Health Science Center at Houston
1989 → 1994
MS, Tongji Medical College, Huazhong University of Science and Technology
1984 → 1986
Surgical Pathology, Postdoctoral Fellowship
Research Area Keywords
- Infectious Disease & Pathology
- Molecular Medicine
Free-text keywords
- Cancer
- Metastasis
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Collaborations and top research areas from the last five years
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International Society of Urological Pathology Consensus Meeting 2024 Working Group 2 Preneoplastic and Precursor Lesions of the Urinary Bladder
the Members of ISUP GU Cancer Precursor Consensus Panel, 2025, (Accepted/In press) In: American Journal of Surgical Pathology.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Interobserver reproducibility of a hybrid three-tier grading system of papillary nonmuscle invasive urothelial carcinoma: an international Uropathology study
Downes, M. R., Lajkosz, K., Algaba, F., Allory, Y., Amin, M. B., Cheng, L., Desai, S., Eckstein, M., Hartmann, A., Lopez-Beltran, A., Mannweiler, S., van Montfoort, M. L., Oxley, J., Paner, G. P., Samaratunga, H., Shen, S., Warrick, J., Williamson, S. R., Wobker, S. E. & van der Kwast, T. H., Nov 2025, In: Histopathology. 87, 5, p. 649-659 11 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations -
Interobserver Reproducibility of Pelvicalyceal Invasion in Renal Cell Carcinoma Nephrectomies Among Genitourinary Pathologists
Sangoi, A. R., Akgul, M., Mubeen, A., Humble, R., Wu, D. J. X., Pacheco, R., Acosta, A., Amin, M., Aron, M., Brimo, F., Chan, E., Cheng, L., Cheville, J., Collins, K., Cornejo, K., Dhillon, J., Downes, M. R., Epstein, J. I., Hirsch, M. & Kapur, P. & 18 others, , 2025, (Accepted/In press) In: American Journal of Surgical Pathology. 10.1097/PAS.0000000000002456.Research output: Contribution to journal › Article › peer-review
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Urothelial carcinoma in situ with “early papillary formation” vs “lateral spread/shoulder lesion” of prior high-grade noninvasive papillary urothelial carcinoma a survey of pathologist and urologist interpretations
Sangoi, A. R., Shahabi, A., Hirsch, M. S., Kao, C. S., Deebajah, M., Barletta, J. A., Paner, G. P., Smith, S. C., Grignon, D. J., Compérat, E., Amin, M. B., Maclean, F., Shah, R. B., Iczkowski, K. A., Delprado, W., Cheng, L., Pan, C. C., McKenney, J. K., Ro, J. Y. & Khani, F. & 11 others, , Apr 1 2025, In: American Journal of Clinical Pathology. 163, 4, p. 629-640 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
International Society of Urological Pathology (ISUP) Consensus Conference on Current Issues in Bladder Cancer. Working Group 1: Comparison of Bladder Cancer Grading System Performance
Downes, M. R., Hartmann, A., Shen, S., Tsuzuki, T., Van Rhijn, B. W. G., Bubendorf, L., Van Der Kwast, T. H. & Cheng, L., Jan 1 2024, In: American Journal of Surgical Pathology. 48, 1, p. E1-E10Research output: Contribution to journal › Article › peer-review
14 Link opens in a new tab Scopus citations