Projects per year
Personal profile
Personal profile
Stephen L. Jones, M.D., M.S.H.I. is a medical informaticist dedicated to raising the standard of care for all patients worldwide. He joined the Department of Surgery and The Houston Methodist Research Institute in July of 2007 after spending the prior 7 years in the medical software industry. While in industry, he held many management roles including co-founder and president of a start-up company. He later served as the clinical systems architect for a practice management and electronic health records company. He has many years of experience designing effective software information systems and managing distributed support and development teams. Software designed, written and developed by teams managed by Dr. Jones is currently responsible for safely and efficiently ePrescribing over 100K prescriptions per month across the nation. He graduated from the University of Texas Health Science Center at Houston Medical School in 1995 and entered an internal medicine residency program at his home institution. It was during this time that he was first exposed to the field of medical informatics and found his true calling in medicine: clinical informatics and decision support leveraging technology to improve health and raise the standard of care. Since joining the Department of Surgery at Houston Methodist Hospital in 2007 he has completed a Master of Science in Health Informatics at The University of Texas School of Biomedical Sciences and completed a post-doctoral fellowship sponsored by the NLM and administered through the Gulf Coast Consortia and the Keck Center for Interdisciplinary Bioscience training at Rice University (NLM Grant No. 5T15LM007093). The NLM fellowship provided invaluable training for working within interdisciplinary teams and multi-institutional projects. His fellowship project was to architect an innovative semi-automated early sepsis screening system, created by Dr. Laura J. Moore and Dr. Fred A. Moore in the Division of Acute and Critical Care Surgery at HMH, to identify patients at risk for developing sepsis while they are hospitalized. The fellowship project tool and research are a central part of an initiative that has saved over 900 lives during the past 7 years at Houston Methodist Hospital and is an integral part of the Sepsis Early Recognition and Response Initiative (SERRI) funded by the CMS Health Care Innovations Challenge (CMS-1C1-12-0001) for $14.3M over a 4 year period. Dr. Jones currently serves as the Chief Clinical Informatics Officer for the Department of Surgery at Houston Methodist Hospital and Division Chief of Health Informatics – Center for Outcomes Research, Houston Methodist Research Institute. He is an Assistant Professor of Clinical Informatics in Surgery, Weill Cornell Medical College. Since 2007 he has co-authored over a dozen peer reviewed papers, one of which has been cited by the Committee on Patient Safety and Health Information Technology; Institute of Medicine, Health IT and Patient Safety: Building Safer Systems for Better Care. Washington, D.C.: The National Academies Press, 2011.
Research interests
Dr. Jones' research centers on the development of customized clinical informatics systems and databases for clinical practice and research.
Research Area Keywords
- Outcomes, Quality & Health Care Performance
- Systems Medicine & Bioinformatics
Free-text keywords
- Clinical informatics
- Quality outcomes
- Database development
- Comparative-effectiveness research
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Collaborations and top research areas from the last five years
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Cardiovascular Disease Health System Registry
Nasir, K. (PI), Al Rifai, M. S. (Key Personnel), Al-Kindi, S. G. (Key Personnel), Avenatti, E. (Key Personnel), Bhimaraj, A. (Key Personnel), Guha, A. (Key Personnel), Javed, Z. (Key Personnel), Jones, S. L. (Key Personnel), Lador, A. (Key Personnel), Malahfji, M. (Key Personnel), Nigo, M. (Key Personnel) & Patel, K. V. (Key Personnel)
3/31/25 → …
Project: Clinical Trial
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Expanding Demographic Representation of PCORnet?
Jones, S. L. (PI)
7/10/23 → 12/31/25
Project: Federal Funding Agencies
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Real World Evidence (RWE) to Accelerate COVID-19 Therapeutics
Jones, S. L. (PI)
1/7/22 → 5/9/22
Project: Federal Funding Agencies
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Development of predictive model and social determinants-based interventions for aggressive prostate cancer among African American males
Esnaola, N. F. (PI), Jones, S. L. (Key Personnel) & Satkunasivam, R. (Key Personnel)
9/30/20 → 9/29/22
Project: Federal Funding Agencies
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SERRI - Sepsis Early Recognition and Response Initiative (CMS-Health Care Innovation Challenge)
Jones, S. L. (PI), Ashton, C. M. (CoI) & Wray, N. (CoI)
Centers for Medicare and Medicaid Svcs
7/1/12 → 6/30/16
Project: Federal Funding Agencies
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Building a Novel Artificial Intelligence–Driven Echocardiographic Data Pipeline: Findings From a Large Learning Health System
Bose, B., Butt, S. A., Arshad, H. B., Nicolas, C. C., Gullapelli, R., Nwana, N., Javed, Z., Shahid, I., Pournazari, P., Patel, K. V., Chamsi Pasha, M. A., Little, S. H., Faza, N. S., Jones, S., Cainzos, M. A., Al-Kindi, S., Saad, J. M., Zoghbi, W., Nagueh, S. F. & Nasir, K., Sep 2024, In: Journal of the American Society of Echocardiography. 37, 9, p. 916-918 3 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Gender disparities in utilization of statins for low density lipoprotein management across the spectrum of atherosclerotic cardiovascular disease: Insights from the houston methodist cardiovascular disease learning health system registry
Shahid, I., Satish, P., Gullapelli, R., Nicholas, J. C., Javed, Z., Avenatti, E., Bose, B., Mahajan, S., Roy, T., Sharma, G., Rodriguez, F., Andrieni, J., Jones, S. L., Al-Kindi, S., Cainzos-Achirica, M. & Nasir, K., Sep 2024, In: American Journal of Preventive Cardiology. 19, p. 100722 100722.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Green Streets, Healthy Hearts: Exploring the Roles of Urban Nature and Walkability in Cardiovascular Health
Nwana, N., Javed, Z., Jones, S. L., Lee, C., Maddock, J. E., Al-Kindi, S. & Nasir, K., 2024, In: Methodist DeBakey cardiovascular journal. 20, 5, p. 37-46 10 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Houston Methodist cardiovascular learning health system (CVD-LHS) registry: Methods for development and implementation of an automated electronic medical record-based registry using an informatics framework approach
Nasir, K., Gullapelli, R., Nicolas, J. C., Bose, B., Nwana, N., Butt, S. A., Shahid, I., Cainzos-Achirica, M., Patel, K. V., Bhimaraj, A., Javed, Z., Andrieni, J., Al-Kindi, S., Jones, S. L. & Zoghbi, W. A., Jun 2024, In: American Journal of Preventive Cardiology. 18, p. 100678 100678.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Neighborhood Walkability Is Associated With Lower Burden of Cardiovascular Risk Factors Among Cancer Patients
Nwana, N., Makram, O. M., Nicolas, J. C., Pan, A., Gullapelli, R., Parekh, T., Javed, Z., Titus, A., Al-Kindi, S., Guan, J., Sun, K., Jones, S. L., Maddock, J. E., Chang, J. & Nasir, K., Jun 2024, In: JACC: CardioOncology. 6, 3, p. 421-435 15 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations