Stephen H. Little, MD, FRCPC, FACC, FASE

  • 2820 Citations
  • 27 h-Index
19992020

Research output per year

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Personal profile

Personal profile

Dr. Little is a cardiologist with the Houston Methodist DeBakey Heart & Vascular Center and program director of the Cardiovascular Fellowship. In addition, he is director of Structural Heart for the Houston Methodist Hospital System, and medical director of the Valve Clinic. He also serves as director of the Cardiovascular Hemodynamics Imaging Laboratory (CHIL).

After completing sub-specialty Cardiology training at the Royal College of Physicians and Surgeon of Canada, Dr. Little completed a postdoctoral fellowship in echocardiography at the Ottawa Heart Institute. He then completed a postdoctoral fellowship, under the supervision of Dr. W. Zoghbi at Baylor College of Medicine, Houston.  In 2007 he was recruited back to Houston to join the Cardiovascular Imaging Institute of Houston Methodist DeBakey Heart & Vascular Center.

He is a fellow of the Royal College of Physicians and Surgeons of Canada, the American College of Cardiology, and the American Society of Echocardiography. For the American Society of Echocardiography, Dr. Little served on the Board of Directors, was chair of the guidelines committee, and is the current vice-president.

Dr. Little has given more than 150 invited lectures nationally and internationally. He is an associate professor of clinical Medicine at Weill Cornell Medical College, and adjunct associate professor at Rice University, Dept. of Bioengineering.

Research interests

Dr. Little’s recent research activities and peer-reviewed publications have focused on novel use of 3D echocardiography for the quantification of native and prosthetic valve dysfunction as well as imaging guidance for percutaneous structural heart interventions. His team has created a robust in vitro flow system for multimodality functional valve imaging under tailored hemodynamic conditions.

As principal investigator, Dr. Little leads Houston Methodists participation in the international Triluminate Clinical Trial of catheter-based therapy for tricuspid valve regurgitation and participates as a co-investigator in multiple other structural heart trials at Houston Methodist.

Education/Academic qualification

Echocardiography, Clinical Fellowship, Baylor College of Medicine

Jul 1 2004Jun 1 2005

Award Date: Jun 1 2005

Internal Medicine, Residency, Western University

Jul 1 1997Jun 1 2003

Award Date: Jun 1 2003

MD, McMaster University School of Medicine

Sep 1 1994May 1 1997

Award Date: May 1 1997

External positions

Associate Professor of Clinical Medicine, Weill Cornell Medical College

Jun 1 2014 → …

Adjunct Associate Professor, Rice University

May 1 2014 → …

Research Area Keywords

  • Heart & Vascular
  • Imaging & Radiology
  • Clinical Translation & Trials
  • Clinical Care

Free-text keywords

  • Valvular disease
  • Mitral regurgitation
  • Echocardiography

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Projects

Research Output

Impact of Stroke Volume Index and Left Ventricular Ejection Fraction on Mortality After Aortic Valve Replacement

Ito, S., Nkomo, V. T., Orsinelli, D. A., Lin, G., Cavalcante, J., Popma, J. J., Adams, D. H., Checuti, S. J., Deeb, G. M., Boulware, M., Huang, J., Little, S. H., Cohen, S. A., Reardon, M. J. & Oh, J. K., Jan 2020, In : Mayo Clinic Proceedings. 95, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

  • 1 Scopus citations
  • Patient-Specific Modeling for Structural Heart Intervention: Role of 3D Printing Today and Tomorrow CME

    Vukicevic, M., Filippini, S. & Little, S. H., Jul 17 2020, In : Methodist DeBakey cardiovascular journal. 16, 2, p. 130-137 8 p.

    Research output: Contribution to journalReview article

  • Role of 3-dimensional transesophageal echocardiography in guiding transcatheter mitral valve replacement

    Faza, N. N. & Little, S. H., Jan 1 2020, In : Echocardiography.

    Research output: Contribution to journalReview article

  • Prizes

    Figure of the month in JACC imaging

    Vukicevic, Marija (Recipient) & Little, Stephen H. (Recipient), Feb 1 2017

    Prize: Other distinction

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