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Personal profile

Research interests

Vision - Dr. Casarin's Research focuses on the development of in silico models to guide pre-clinical and clinical research in a more robust and more effective fashion. Working side-by-side with biologist and clinicians, Dr. Casarin and his team aim to create data-integrated in silico platforms with the ultimate goal of prioritizing therapeutic approaches that will most likely succeed and de-prioritizing the ones that will most likely fail.

Active projects - The fields of interest of Dr. Casarin mostly include vascular, cancer, and transplants:

  1. Vascular: i) modeling of atherosclerotic plaque formation in superior femoral arteries; ii) modeling of restenosis phenomenon in vein graft bypasses during post-surgical vascular adaptation; iii) in silico platform to optimize the development of gene therapies to improve the life expectancy of vein graft bypasses
  2. Cancer: i) modeling of prostate cancer bone metastasis establishment, development, and response to therapeutic agents; ii) application of neural networks to the identification of cellular nuceli of interest in the phenomenon of foreign body response; iii) modeling of colon-rectal cancer development and metastatic spreading
  3. Transplant: clinical data-driven in silico platform to optimize the management of brain dead donor patients for solid organ transplantation.

Education/Academic qualification

Applied Mathematical Sciences, PhD, Mathematical Models in Computational Surgery, Université de La Rochelle

Nov 1 2013Jun 17 2017

Award Date: Jun 17 2017

Biomedical Engineering, MS, Politecnico Di Milano

Oct 1 2010Oct 3 2013

Award Date: Oct 3 2013

Biomedical Engineering, BS, Universita di Padova

Oct 1 2006Mar 26 2010

Award Date: Mar 26 2010

External positions

Adjunct Professor, University of La Rochelle

Mar 1 2022 → …

Research Area Keywords

  • Transplantation
  • Cancer
  • Systems Medicine & Bioinformatics
  • Heart & Vascular
  • Immunobiology & Inflammation

Free-text keywords

  • Computational Biology


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