Research interests

Vision - Dr. Casarin's Research focuses on the development of in silico models to guide pre-clinical and clinical Research in a more robust and more effectivr fashion. Working side-by-side wit biologist and clinicians, Dr. Casarin and his team am to create data-integrated in silico platforms with the ultimate goal of prioritizing thrapeturic approaches that will most likely succeed and de-prioritizing the ones that will most liley fail.

Active projects - The fields of interest of Dr. Casarin mostly include vascular, cancer, and transplants:

  1. Vascular: i) modeling of atherosclerotic plaque formation in superior femoral arteries; ii) modeling of restenosis phenomenon in vein graft bypasses during post-surgical vascular adaptation; iii) in silico platform to optimize the development of gene therapies to improve the life expectancy of vein graft bypasses
  2. Cancer: i) modeling of prostate cancer bone metastasis establishment, development, and response to therapeutic agents; ii) application of neural networks to the identification of cellular nuceli of interest in the phenomenon of foreign body response; iii) modeling of colon-rectal cancer development and metastatic spreading
  3. Transplant: clinical data-driven in silico platform to optimize the management of brain dead donor patients for solid organ transplantation.

Keywords

    Research Area Keywords

  • Transplantation
  • Cancer
  • Systems Medicine & Bioinformatics
  • Heart & Vascular
  • Immunobiology & Inflammation

    Free-text keywords

  • Computational Biology

Fingerprint

Agent-based Model
Concept: Agent-based Model
Weight: 100%
Domain: Mathematics
Grafts
Concept: Grafts
Weight: 89%
Domain: Engineering & Materials Science
Blood Vessels
Concept: Blood Vessels
Weight: 77%
Domain: Medicine & Life Sciences
Partial differential equations
Concept: Partial differential equations
Weight: 63%
Domain: Engineering & Materials Science
Transplants
Concept: Transplants
Weight: 62%
Domain: Medicine & Life Sciences
Veins
Concept: Veins
Weight: 57%
Domain: Mathematics
Computational Model
Concept: Computational Model
Weight: 56%
Domain: Mathematics
Restenosis
Concept: Restenosis
Weight: 45%
Domain: Mathematics
Computational fluid dynamics
Concept: Computational fluid dynamics
Weight: 38%
Domain: Engineering & Materials Science
Bone Neoplasms
Concept: Bone Neoplasms
Weight: 36%
Domain: Medicine & Life Sciences
Research OutputsResearch Output authored by Stefano Casarin is tagged with the concept

Journals

PLoS ONE

Additional searchable ISSN (Electronic): 1932-6203

Public Library of Science

Journal

1

Journal of the National Cancer Institute

ISSNs: 0027-8874

Oxford University Press

Journal

1

Computers in Biology and Medicine

ISSNs: 0010-4825

Elsevier Limited

Journal

1

Biomechanics and Modeling in Mechanobiology

ISSNs: 1617-7959

Additional searchable ISSN (Electronic): 1617-7940

Springer Verlag

Journal

1

Acta Mechanica Sinica/Lixue Xuebao

ISSNs: 0567-7718

Springer Verlag

Journal

1
has published Research OutputsResearch Output by Stefano Casarin

Research Network

Visualization: Institutional Network

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Stefano Casarin

Visualization: Co-author Network

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Stefano Casarin

Shared Pub. Internal Organizations

Center for Computational Surgery

Organizational unit: Programs

13
has Research OutputsResearch Output by Stefano Casarin

Shared Pub. External Organizations

Veterans Affairs Medical Center

External organization: Unknown

7

University of Florida College of Medicine

External organization: Unknown

7

Politecnico di Milano

External organization: Unknown

2

Politecnico di Torino

External organization: Unknown

2

Department of Surgery, University of Florida, Gainesville, FL, USA.

External organization: Unknown

1
has Research OutputsResearch Output by Stefano Casarin

Shared Pub. Internal co-authors

has co-authored Research OutputsResearch Output with Stefano Casarin

Shared Pub. External co-authors

Scott Berceli

External person

8

Francesco Migliavacca

External person

2

Scott A. Berceli

External person

2

Anna Corti

External person

2

Monika Colombo

External person

2
has co-authored Research OutputsResearch Output with Stefano Casarin

ID: 54116998