• 37 Citations
  • 4 h-Index
20152020

Research output per year

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Personal profile

Research interests

Vision - Dr. Casarin's Research focuses on the development of in silico models to guide pre-clinical and clinical Research in a more robust and more effectivr fashion. Working side-by-side wit biologist and clinicians, Dr. Casarin and his team am to create data-integrated in silico platforms with the ultimate goal of prioritizing thrapeturic approaches that will most likely succeed and de-prioritizing the ones that will most liley fail.

Active projects - The fields of interest of Dr. Casarin mostly include vascular, cancer, and transplants:

  1. Vascular: i) modeling of atherosclerotic plaque formation in superior femoral arteries; ii) modeling of restenosis phenomenon in vein graft bypasses during post-surgical vascular adaptation; iii) in silico platform to optimize the development of gene therapies to improve the life expectancy of vein graft bypasses
  2. Cancer: i) modeling of prostate cancer bone metastasis establishment, development, and response to therapeutic agents; ii) application of neural networks to the identification of cellular nuceli of interest in the phenomenon of foreign body response; iii) modeling of colon-rectal cancer development and metastatic spreading
  3. Transplant: clinical data-driven in silico platform to optimize the management of brain dead donor patients for solid organ transplantation.

Education/Academic qualification

Applied Mathematical Sciences, PhD, Université de La Rochelle

Nov 1 2013Jun 17 2017

Award Date: Jun 17 2017

Biomedical Engineering, MS, Politecnico Di Milano

Oct 1 2010Oct 3 2013

Award Date: Oct 3 2013

Biomedical Engineering, BS, Universita di Padova

Oct 1 2006Mar 26 2010

Award Date: Mar 26 2010

Research Area Keywords

  • Transplantation
  • Cancer
  • Systems Medicine & Bioinformatics
  • Heart & Vascular
  • Immunobiology & Inflammation

Free-text keywords

  • Computational Biology

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Research Output

  • 37 Citations
  • 4 h-Index
  • 10 Article
  • 3 Conference contribution
  • 1 Chapter
  • 1 Paper

A fully coupled computational fluid dynamics – agent-based model of atherosclerotic plaque development: Multiscale modeling framework and parameter sensitivity analysis

Corti, A., Chiastra, C., Colombo, M., Garbey, M., Migliavacca, F. & Casarin, S., Mar 1 2020, In : Computers in Biology and Medicine. 118, 103623.

Research output: Contribution to journalArticle

  • 1 Scopus citations

    An agent-based model of prostate Cancer bone metastasis progression and response to Radium223

    Casarin, S. & Dondossola, E., Jun 29 2020, In : BMC Cancer. 20, 1, 605.

    Research output: Contribution to journalArticle

    Open Access
  • A Multiscale Model of Atherosclerotic Plaque Development: Toward a Coupling Between an Agent-Based Model and CFD Simulations

    Corti, A., Casarin, S., Chiastra, C., Colombo, M., Migliavacca, F. & Garbey, M., Jan 1 2019, Computational Science – ICCS 2019 - 19th International Conference, Proceedings. Rodrigues, J. M. F., Cardoso, P. J. S., Monteiro, J., Lam, R., Krzhizhanovskaya, V. V., Lees, M. H., Sloot, P. M. A. & Dongarra, J. J. (eds.). Springer-Verlag, p. 410-423 14 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11539 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  • 1 Scopus citations

    A versatile hybrid agent-based, particle and partial differential equations method to analyze vascular adaptation

    Garbey, M., Casarin, S. & Berceli, S. A., Feb 15 2019, In : Biomechanics and Modeling in Mechanobiology. 18, 1, p. 29-44 16 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations

    Radium 223-Mediated Zonal Cytotoxicity of Prostate Cancer in Bone

    Dondossola, E., Casarin, S., Paindelli, C., De-Juan-Pardo, E. M., Hutmacher, D. W., Logothetis, C. J. & Friedl, P., Jan 18 2019, In : Journal of the National Cancer Institute. 111, 10, p. 1042-1050 9 p.

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Prizes

    Best Paper

    Casarin, Stefano (Recipient), Jun 6 2017

    Prize: Prize (including medals and awards)

    Young Researcher Prize

    Casarin, Stefano (Recipient), Oct 18 2019

    Prize: Prize (including medals and awards)