Rongfu Wang

Personal profile

Dr. Wang received his Ph.D. from the University of Georgia in 1992. After receiving his doctoral degree in Molecular Genetics, Dr. Wang expanded his field of expertise by training with Dr. James Mullins in the Department of Microbiology and Immunology at Stanford University School of Medicine. In 1994, Dr. Wang joined the Surgery Branch in the Center for Cancer Research at the National Cancer Institute (NCI) in Bethesda, Maryland where he worked with Branch Chief, Dr. Steve Rosenberg, who is a pioneer of cancer immunotherapy. In 1996, Dr. Wang was promoted to Senior Principal Investigator. During his tenure at the NCI, Dr. Wang made insightful discoveries on how immune cells recognize solid tumors through specific cancer antigens and published a landmark paper in Science on the development of a novel genetic approach to identify cancer antigens recognized by CD4+ T cells. In 2000, Dr. Wang was appointed Associate Professor at Baylor College of Medicine in the Center for Cell and Gene Therapy and the Department of Pathology and Immunology. He was promoted to full Professor in 2004. His lab studies novel mechanisms in tumor immunity and tolerance, innate immune regulation, regulatory T cell biology, inflammation, and epigenetics.

Throughout his career Dr. Wang has published over hundred papers in the top class of journals, including Science, Cell, Nature Biotechnology, Nature Immunology, Cell Metabolism and Immunity, and has over 20 patents. His work has been supported by many grants from NIH, DoD, American Cancer Society, Cancer Research Institute and CPRIT.

Research interests

Research interests in Dr. Wang's laboratory include

cancer immunotherapy,
immune regulation in infectious and tumor immunity;
innate immune signaling and inflammation in diseases, 3) epigenetic reprogramming of cancer and immune cells.

Education/Academic qualification

Molecular Virology, Postdoctoral Fellowship, Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA

Cancer Immunotherapy, Postdoctoral Fellowship, Surgery Branch, National Cancer Institute, Bethesda, MD

Molecular Genetics, PhD, University of Georgia

Free-text keywords

Cancer immunology
Innate immune signaling
Epigenetics of cancer and stem cells
Cancer immunotherapy

Research Area Keywords

Cancer
Immunobiology & Inflammation

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Projects

4 Active
11 Finished

Center for Immunotherapeutic Transport Oncophysics

Shen, H., Herzog, T., Kojic, M., Li, Z., Liu, X., Schrefler, B. A., Tasciotti, E., Wang, R. & Ziemys, A.

National Institutes of Health

8/29/16 → 7/31/21

Project: Federal Funding Agencies

CPRIT Core for RNA Therapeutics and Research

Cooke, J. P., Bruno, I. G., Wang, R. & Yakubov, E.

Cancer Prevention and Res Inst of Texas

6/1/15 → 11/30/20

Project: State

Novel Strategies for Intervention of Inflammatory Diseases and Cancer - Research Supplement to R01-CA101795

Wang, R.

7/1/04 → 6/30/23

Project: Federal Funding Agencies

Novel Strategies for Intervention of Inflammatory Diseases and Cancer

Wang, R. & Peterson, L. E.

7/1/04 → 6/30/23

Project: Federal Funding Agencies

Identification of novel immune targets and neoantigens for development of immunotherapy for breast cancer

Wang, R., Chang, J. C., Liu, X. & Wang, H.

12/1/16 → 11/30/19

Project: State

Research Output

10459 Citations
55 h-Index
108 Article
23 Review article
6 Chapter
2 Comment/debate
5 More

Beclin 2 negatively regulates innate immune signaling and tumor development

Zhu, M., Deng, G., Tan, P., Xing, C., Guan, C., Jiang, C., Zhang, Y., Ning, B., Li, C., Yin, B., Chen, K., Zhao, Y., Wang, H. Y., Levine, B., Nie, G. & Wang, R. F., Oct 1 2020, In : Journal of Clinical Investigation. 130, 10, p. 5349-5369 21 p.