Research output per year
Research output per year
- 26 results
Search results
-
2023
Machine learning dissection of human accelerated regions in primate neurodevelopment
Whalen, S., Inoue, F., Ryu, H., Fair, T., Markenscoff-Papadimitriou, E., Keough, K., Kircher, M., Martin, B., Alvarado, B., Elor, O., Laboy Cintron, D., Williams, A., Hassan Samee, M. A., Thomas, S., Krencik, R., Ullian, E. M., Kriegstein, A., Rubenstein, J. L., Shendure, J., Pollen, A. A., & 2 others, Mar 15 2023, In: Neuron. 111, 6, p. 857-873.e8Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2022
Assessing Gq-GPCR–induced human astrocyte reactivity using bioengineered neural organoids
Cvetkovic, C., Patel, R., Shetty, A., Hogan, M. K., Anderson, M., Basu, N., Aghlara-Fotovat, S., Ramesh, S., Sardar, D., Veiseh, O., Ward, M. E., Deneen, B., Horner, P. J. & Krencik, R., Feb 9 2022, In: Journal of Cell Biology. 221, 4, e202107135.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Machine-learning dissection of Human Accelerated Regions in primate neurodevelopment
Whalen, S., Inoue, F., Ryu, H., Fairr, T., Markenscoff-Papadimitriou, E., Keough, K., Kircher, M., Martin, B., Alvarado, B., Elor, O., Cintron, D., Williams, A., Samee, M. A. H., Thomas, S., Krencik, R. C., Ullian, E., Kriegstein, A., Rubenstein, J., Shendure, J., Pollen, A., & 2 others, Sep 28 2022, In: bioRxiv.Research output: Contribution to journal › Article
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2021
DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases
Zhang, N., Bewick, B., Schultz, J., Tiwari, A., Krencik, R., Zhang, A., Adachi, K., Xia, G., Yun, K., Sarkar, P. & Ashizawa, T., Jul 2021, In: Neurotherapeutics. 18, 3, p. 1710-1728 19 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Humanized Biomimetic Nanovesicles for Neuron Targeting
Zinger, A., Cvetkovic, C., Sushnitha, M., Naoi, T., Baudo, G., Anderson, M., Shetty, A., Basu, N., Covello, J., Tasciotti, E., Amit, M., Xie, T., Taraballi, F. & Krencik, R., Oct 6 2021, In: Advanced Science. 8, 19, p. e2101437 2101437.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Mapping astrocyte transcriptional signatures in response to neuroactive compounds
Sardar, D., Lozzi, B., Woo, J., Huang, T. W., Cvetkovic, C., Creighton, C. J., Krencik, R. & Deneen, B., Apr 2 2021, In: International journal of molecular sciences. 22, 8, 3975.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Targeting the extracellular matrix for immunomodulation: applications in drug delivery and cell therapies
Aghlara-Fotovat, S., Nash, A., Kim, B., Krencik, R. & Veiseh, O., Dec 2021, In: Drug Delivery and Translational Research. 11, 6, p. 2394-2413 20 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2018
Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes
Jones, J. R., Kong, L., Hanna, M. G., Hoffman, B., Krencik, R., Bradley, R., Hagemann, T., Choi, J., Doers, M., Dubovis, M., Sherafat, M. A., Bhattacharyya, A., Kendziorski, C., Audhya, A., Messing, A. & Zhang, S. C., Oct 23 2018, In: Cell Reports. 25, 4, p. 947-958.e4Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment
Yeh, E., Dao, D. Q., Wu, Z. Y., Kandalam, S. M., Camacho, F. M., Tom, C., Zhang, W., Krencik, R., Rauen, K. A., Ullian, E. M. & Weiss, L. A., Aug 1 2018, In: Molecular Psychiatry. 23, 8, p. 1687-1698 12 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Synaptic microcircuit modeling with 3D cocultures of astrocytes and neurons from human pluripotent stem cells
Cvetkovic, C., Basu, N. & Krencik, R., Aug 16 2018, In: Journal of visualized experiments : JoVE. 2018, 138, e58034.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
2017
Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner
Krejciova, Z., Alibhai, J., Zhao, C., Krencik, R., Rzechorzek, N. M., Ullian, E. M., Manson, J., Ironside, J. W., Head, M. W. & Chandran, S., Dec 4 2017, In: The Journal of experimental medicine. 214, 12, p. 3481-3495 15 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes
Krencik, R., Seo, K., van Asperen, J. V., Basu, N., Cvetkovic, C., Barlas, S., Chen, R., Ludwig, C., Wang, C., Ward, M. E., Gan, L., Horner, P. J., Rowitch, D. H. & Ullian, E. M., Dec 12 2017, In: Stem Cell Reports. 9, 6, p. 1745-1753 9 p.Research output: Contribution to journal › Article › peer-review
71 Scopus citations -
2016
Directed differentiation of basal forebrain cholinergic neurons from human pluripotent stem cells
Hu, Y., Qu, Z-Y., Cao, S-Y., Li, Q., Ma, L., Krencik, R., Xu, M. & Liu, Y., Jun 15 2016, In: Journal of Neuroscience Methods. 266, p. 42-9 8 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Human astrocytes are distinct contributors to the complexity of synaptic function
Krencik, R., van Asperen, J. V. & Ullian, E. M., Aug 25 2016, In: Brain Research Bulletin.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Zika virus cell tropism in the developing human brain and inhibition by azithromycin
Retallack, H., Di Lullo, E., Arias, C., Knopp, K. A., Laurie, M. T., Sandoval-Espinosa, C., Mancia Leon, W. R., Krencik, R., Ullian, E. M., Spatazza, J., Pollen, A. A., Mandel-Brehm, C., Nowakowski, T. J., Kriegstein, A. R. & DeRisi, J. L., Dec 13 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. 14408-14413 6 p.Research output: Contribution to journal › Article › peer-review
376 Scopus citations -
2015
Dysregulation of astrocyte extracellular signaling in Costello syndrome
Krencik, R., Hokanson, K. C., Narayan, A. R., Dvornik, J., Rooney, G. E., Rauen, K. A., Weiss, L. A., Rowitch, D. H. & Ullian, E. M., May 6 2015, In: Science translational medicine. 7, 286, p. 286ra66Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
Efficient generation of region-specific forebrain neurons from human pluripotent stem cells under highly defined condition
Yuan, F., Fang, K-H., Cao, S-Y., Qu, Z-Y., Li, Q., Krencik, R., Xu, M., Bhattacharyya, A., Su, Y-W., Zhu, D-Y. & Liu, Y., Dec 16 2015, In: Scientific Reports. 5, p. 18550Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
2013
A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies
Krencik, R. & Ullian, E. M., 2013, In: Frontiers in Cellular Neuroscience. 7, p. 25Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits
Liu, Y., Weick, J. P., Liu, H., Krencik, R., Zhang, X., Ma, L., Zhou, G., Ayala, M. & Zhang, S-C., May 2013, In: Nature Biotechnology. 31, 5, p. 440-7 8 p.Research output: Contribution to journal › Article › peer-review
210 Scopus citations -
2012
Astrocytes and disease: a neurodevelopmental perspectiv
Molofsky, A. V., Krencik, R., Ullian, E. M., Ullian, E., Tsai, H., Deneen, B., Richardson, W. D., Barres, B. A. & Rowitch, D. H., May 1 2012, In: Genes & development. 26, 9, p. 891-907 17 p.Research output: Contribution to journal › Article › peer-review
541 Scopus citations -
2011
Directed differentiation of functional astroglial subtypes from human pluripotent stem cells
Krencik, R. & Zhang, S-C., Oct 13 2011, In: Nature Protocols. 6, 11, p. 1710-7 8 p.Research output: Contribution to journal › Article › peer-review
204 Scopus citations -
Specification of transplantable astroglial subtypes from human pluripotent stem cells
Krencik, R., Weick, J. P., Liu, Y., Zhang, Z-J. & Zhang, S-C., May 22 2011, In: Nature Biotechnology. 29, 6, p. 528-34 7 p.Research output: Contribution to journal › Article › peer-review
332 Scopus citations -
2008
The COOH-terminal domain of the JIL-1 histone H3S10 kinase interacts with histone H3 and is required for correct targeting to chromatin
Bao, X., Cai, W., Deng, H., Zhang, W., Krencik, R., Girton, J., Johansen, J. & Johansen, K. M., Nov 21 2008, In: The Journal of biological chemistry. 283, 47, p. 32741-50 10 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2006
Stem cell neural differentiation: A model for chemical biology
Krencik, R. & Zhang, S-C., Dec 2006, In: Current Opinion in Chemical Biology. 10, 6, p. 592-7 6 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
2005
The JIL-1 kinase interacts with lamin Dm0 and regulates nuclear lamina morphology of Drosophila nurse cells
Bao, X., Zhang, W., Krencik, R., Deng, H., Wang, Y., Girton, J., Johansen, J. & Johansen, K. M., Nov 1 2005, In: Journal of Cell Science. 118, Pt 21, p. 5079-87 9 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2004
Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells
Kweon, G-R., Marks, J. D., Krencik, R., Leung, E. H., Schumacker, P. T., Hyland, K. & Kang, U. J., Dec 10 2004, In: The Journal of biological chemistry. 279, 50, p. 51783-92 10 p.Research output: Contribution to journal › Article › peer-review
65 Scopus citations