• 1320 Citations
  • 15 h-Index
20042020

Research output per year

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Research Output

  • 1320 Citations
  • 15 h-Index
  • 19 Article
  • 1 Review article
  • 1 Web publication/site
2018

Concepts toward directing human astroplasticity to promote neuroregeneration

Patel, R., Muir, M., Cvetkovic, C. & Krencik, R., Jul 17 2018, In : Developmental Dynamics. p. 21-33 248.

Research output: Contribution to journalReview article

1 Scopus citations

Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes

Jones, J. R., Kong, L., Hanna, M. G., Hoffman, B., Krencik, R., Bradley, R., Hagemann, T., Choi, J., Doers, M., Dubovis, M., Sherafat, M. A., Bhattacharyya, A., Kendziorski, C., Audhya, A., Messing, A. & Zhang, S. C., Oct 23 2018, In : Cell Reports. 25, 4, p. 947-958.e4

Research output: Contribution to journalArticle

13 Scopus citations

Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment

Yeh, E., Dao, D. Q., Wu, Z. Y., Kandalam, S. M., Camacho, F. M., Tom, C., Zhang, W., Krencik, R., Rauen, K. A., Ullian, E. M. & Weiss, L. A., Aug 1 2018, In : Molecular Psychiatry. 23, 8, p. 1687-1698 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Synaptic microcircuit modeling with 3D cocultures of astrocytes and neurons from human pluripotent stem cells

Cvetkovic, C., Basu, N. & Krencik, R., Aug 16 2018, In : Journal of visualized experiments : JoVE. 2018, 138, e58034.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner

Krejciova, Z., Alibhai, J., Zhao, C., Krencik, R., Rzechorzek, N. M., Ullian, E. M., Manson, J., Ironside, J. W., Head, M. W. & Chandran, S., Dec 4 2017, In : The Journal of experimental medicine. 214, 12, p. 3481-3495 15 p.

Research output: Contribution to journalArticle

22 Scopus citations

Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes

Krencik, R., Seo, K., van Asperen, J. V., Basu, N., Cvetkovic, C., Barlas, S., Chen, R., Ludwig, C., Wang, C., Ward, M. E., Gan, L., Horner, P. J., Rowitch, D. H. & Ullian, E. M., Dec 12 2017, In : Stem Cell Reports. 9, 6, p. 1745-1753 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2016

Directed differentiation of basal forebrain cholinergic neurons from human pluripotent stem cells

Hu, Y., Qu, Z-Y., Cao, S-Y., Li, Q., Ma, L., Krencik, R., Xu, M. & Liu, Y., Jun 15 2016, In : Journal of Neuroscience Methods. 266, p. 42-9 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Human astrocytes are distinct contributors to the complexity of synaptic function

Krencik, R., van Asperen, J. V. & Ullian, E. M., Aug 25 2016, In : Brain Research Bulletin.

Research output: Contribution to journalArticle

18 Scopus citations

Targeting brain’s star-shaped cells may yield autism drugs

Krencik, R., May 3 2016

Research output: Non-textual formWeb publication/site

Zika virus cell tropism in the developing human brain and inhibition by azithromycin

Retallack, H., Di Lullo, E., Arias, C., Knopp, K. A., Laurie, M. T., Sandoval-Espinosa, C., Mancia Leon, W. R., Krencik, R., Ullian, E. M., Spatazza, J., Pollen, A. A., Mandel-Brehm, C., Nowakowski, T. J., Kriegstein, A. R. & DeRisi, J. L., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. 14408-14413 6 p.

Research output: Contribution to journalArticle

196 Scopus citations
2015

Dysregulation of astrocyte extracellular signaling in Costello syndrome

Krencik, R., Hokanson, K. C., Narayan, A. R., Dvornik, J., Rooney, G. E., Rauen, K. A., Weiss, L. A., Rowitch, D. H. & Ullian, E. M., May 6 2015, In : Science translational medicine. 7, 286, p. 286ra66

Research output: Contribution to journalArticle

39 Scopus citations

Efficient generation of region-specific forebrain neurons from human pluripotent stem cells under highly defined condition

Yuan, F., Fang, K-H., Cao, S-Y., Qu, Z-Y., Li, Q., Krencik, R., Xu, M., Bhattacharyya, A., Su, Y-W., Zhu, D-Y. & Liu, Y., Dec 16 2015, In : Scientific Reports. 5, p. 18550

Research output: Contribution to journalArticle

26 Scopus citations
2013
23 Scopus citations

Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits

Liu, Y., Weick, J. P., Liu, H., Krencik, R., Zhang, X., Ma, L., Zhou, G., Ayala, M. & Zhang, S-C., May 2013, In : Nature Biotechnology. 31, 5, p. 440-7 8 p.

Research output: Contribution to journalArticle

127 Scopus citations
2012

Astrocytes and disease: a neurodevelopmental perspectiv

Molofsky, A. V., Krencik, R., Ullian, E. M., Ullian, E., Tsai, H., Deneen, B., Richardson, W. D., Barres, B. A. & Rowitch, D. H., May 1 2012, In : Genes & development. 26, 9, p. 891-907 17 p.

Research output: Contribution to journalArticle

351 Scopus citations
2011

Directed differentiation of functional astroglial subtypes from human pluripotent stem cells

Krencik, R. & Zhang, S-C., Oct 13 2011, In : Nature Protocols. 6, 11, p. 1710-7 8 p.

Research output: Contribution to journalArticle

121 Scopus citations

Specification of transplantable astroglial subtypes from human pluripotent stem cells

Krencik, R., Weick, J. P., Liu, Y., Zhang, Z-J. & Zhang, S-C., May 22 2011, In : Nature Biotechnology. 29, 6, p. 528-34 7 p.

Research output: Contribution to journalArticle

227 Scopus citations
2008

The COOH-terminal domain of the JIL-1 histone H3S10 kinase interacts with histone H3 and is required for correct targeting to chromatin

Bao, X., Cai, W., Deng, H., Zhang, W., Krencik, R., Girton, J., Johansen, J. & Johansen, K. M., Nov 21 2008, In : The Journal of biological chemistry. 283, 47, p. 32741-50 10 p.

Research output: Contribution to journalArticle

13 Scopus citations
2006

Stem cell neural differentiation: A model for chemical biology

Krencik, R. & Zhang, S-C., Dec 2006, In : Current Opinion in Chemical Biology. 10, 6, p. 592-7 6 p.

Research output: Contribution to journalArticle

23 Scopus citations
2005

The JIL-1 kinase interacts with lamin Dm0 and regulates nuclear lamina morphology of Drosophila nurse cells

Bao, X., Zhang, W., Krencik, R., Deng, H., Wang, Y., Girton, J., Johansen, J. & Johansen, K. M., Nov 1 2005, In : Journal of Cell Science. 118, Pt 21, p. 5079-87 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2004

Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells

Kweon, G-R., Marks, J. D., Krencik, R., Leung, E. H., Schumacker, P. T., Hyland, K. & Kang, U. J., Dec 10 2004, In : The Journal of biological chemistry. 279, 50, p. 51783-92 10 p.

Research output: Contribution to journalArticle

59 Scopus citations