After completing a neuroradiology fellowship at Tufts-New England Medical Center, Dr. Klucznik served as the chief of neuroradiology CT/MRI at the Wilford Hall USAF Medical Center of the Lackland Air Force Base in San Antonio, Texas where he received the Air Force Commendation Medal. He then completed an interventional neuroradiology fellowship at Baylor College of Medicine in Houston, Texas and subsequently was appointed Assistant Professor of Radiology at BCM in 1996. Dr. Klucznik joined the staff at The Methodist Hospital that same year as an interventional neuroradiologist and was appointed Director of Interventional Neuroradiology at TMH in 2005. Since joining Methodist, Dr. Klucznik has served on numerous committees including the Medical Staff Quality Management Committee, Neurology Care Management Performance Improvement Subcommittee and the Quality Assurance Committee for Endovascular, which he chaired in 2006.

Dr. Klucznik conducts clinical and translational studies to evaluate the safety and efficacy of endovascular treatments for various neurological disorders.