Personal profile

Dr. El-Zein earned her Medical Degree followed by a Masters in Human Genetics from the University of Alexandria. She then completed her Doctoral degree in Human Biological Chemistry and Genetics at the University of Texas Medical Branch with a focus on cancer genetics. In 1997, she joined the University of Texas MD Anderson Cancer Center as a postdoctoral fellow and rose through the ranks to Associate Professor in the Department of Epidemiology. In 2015, Dr. El-Zein joined Houston Methodist as a Professor in the Department of Radiology and a full member of the Research Institute.

Dr. El-Zein is an active member of the national and international scientific community. She serves/served as a reviewer for the National Institute of Health, National Lung, Heart and Blood Institute and the American Cancer Society. Internationally, she is a grant reviewer for the Italian Ministry of Health. Dr. El-Zein also serves as a peer reviewer for several high impact journals.

Research interests

Dr. El-Zein’s research focus is on understanding the role of gene-environment interactions in the risk of cancer development. She has developed expertise in the area of biomarkers and genetic susceptibility to disease. She has applied unique markers to identify several inherited genetic traits that influence human sensitivity to different cancers such as lung, breast and lymphomas. Dr. El-Zein’s laboratory has a translational research approach, and is currently studying human populations using quantitative imaging coupled with molecular biomarkers to identify unique signatures that would improve the power of cancer risk assessment models. The results from these studies are providing new information that has significant and practical public health implications in the area of early detection and primary prevention of disease. The overall goal is to develop novel approaches to identify susceptible individuals at high risk of developing lung and breast cancers. New knowledge generated from these research endeavors are geared to fulfill the need for rapid and efficient translation of emerging new technologies and approaches for improved patient management, early detection and prevention.Dr. El-Zein’s research focus is on understanding the role of gene-environment interactions in the risk of cancer development. She has developed expertise in the area of genotypic and phenotypic biomarkers and genetic susceptibility to disease. She has applied these unique markers to identify several inherited genetic traits that influence human sensitivity to different cancers such as lung, breast and lymphomas. Dr. El-Zein’s laboratory has a translational research approach, and is currently studying human populations using quantitative imaging coupled with molecular biomarkers to identify unique signatures that would improve the power of cancer risk assessment models. The results from these studies are providing new information that has significant and practical public health implications in the area of early detection and primary prevention of disease. The overall goal is to develop novel approaches to identify susceptible individuals at high risk of developing lung and breast cancers. New knowledge generated from these research endeavors are geared to fulfill the need for rapid and efficient translation of emerging new technologies and approaches for improved patient management, early detection and prevention.

Keywords

    Research Area Keywords

  • Cancer
  • Precision Medicine
  • Imaging & Radiology

    Free-text keywords

  • Lung cancer, Breast cancer, Genetic instability, Genetic susceptibility

External positions

Adjunct Professor, The University of Texas MD Anderson Cancer Center

Sep 1 2016 → …

Adjunct Associate Professor of Epidemiology, University of Texas School of Public Helath

Sep 1 2009 → …

Fingerprint

Lung Neoplasms
Concept: Lung Neoplasms
Weight: 100%
Domain: Medicine & Life Sciences
Inflammatory Breast Neoplasms
Concept: Inflammatory Breast Neoplasms
Weight: 62%
Domain: Medicine & Life Sciences
Neoplasms
Concept: Neoplasms
Weight: 53%
Domain: Medicine & Life Sciences
Glioma
Concept: Glioma
Weight: 53%
Domain: Medicine & Life Sciences
Genes
Concept: Genes
Weight: 52%
Domain: Medicine & Life Sciences
Lymphocytes
Concept: Lymphocytes
Weight: 49%
Domain: Medicine & Life Sciences
Cytokinesis
Concept: Cytokinesis
Weight: 49%
Domain: Medicine & Life Sciences
DNA Repair
Concept: DNA Repair
Weight: 47%
Domain: Medicine & Life Sciences
Micronucleus Tests
Concept: Micronucleus Tests
Weight: 45%
Domain: Medicine & Life Sciences
Chromosome Aberrations
Concept: Chromosome Aberrations
Weight: 44%
Domain: Medicine & Life Sciences
Research OutputsResearch Output authored by Randa El-Zein is tagged with the concept

Journals

Cancer Epidemiology Biomarkers and Prevention

ISSNs: 1055-9965

American Association for Cancer Research Inc.

Journal

7

Cancer Letters

ISSNs: 0304-3835

Elsevier Ireland Ltd

Journal

6

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

ISSNs: 0027-5107

Elsevier

Journal

4

Cancer Research

ISSNs: 0008-5472

American Association for Cancer Research Inc.

Journal

4

Environmental and Molecular Mutagenesis

ISSNs: 0893-6692

Wiley

Journal

4
has published Research OutputsResearch Output by Randa El-Zein

Research Network

Visualization: Institutional Network

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Randa El-Zein

Visualization: Co-author Network

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Randa El-Zein

Shared Pub. External Organizations

University of Texas M. D. Anderson Cancer Center

External organization: Unknown

59

UT Medical Branch at Galveston

External organization: Unknown

27

Baylor College of Medicine

External organization: Unknown

10

University of Texas MD Anderson Cancer Center

External organization: Academic

8

M. D. Anderson Cancer Center

External organization: Unknown

6
has Research OutputsResearch Output by Randa El-Zein

Shared Pub. Internal co-authors

has co-authored Research OutputsResearch Output with Randa El-Zein

Shared Pub. External co-authors

Melissa Bondy

External person

24

Carol J. Etzel

External person

24

Sherif Z. Abdel-Rahman

External person

21

William Au

External person

12

Mirtha S. Lopez

External person

12
has co-authored Research OutputsResearch Output with Randa El-Zein

ID: 16693912